NIOSH Pocket Guide to Chemical Hazards

p-Anisidine CAS 104-94-9
NH2C6H4OCH3 RTECS BZ5450000
Synonyms & Trade Names
para-Aminoanisole, 4-Anisidine, p-Methoxyaniline
DOT ID & Guide
2431 153
Exposure
Limits
NIOSH REL: TWA 0.5 mg/m3 [skin]
OSHA PEL: TWA 0.5 mg/m3 [skin]
IDLH 50 mg/m3 See: 104949 Conversion
Physical Description
Yellow to brown, crystalline solid with an amine-like odor.
MW: 123.2
BP: 475°F
MLT: 135°F
Sol: Moderate
VP(77°F): 0.006 mmHg
IP: 7.44 eV

Sp.Gr: 1.07
Fl.P: ?
UEL: ?
LEL: ?

Combustible Solid
Incompatibilities & Reactivities
Strong oxidizers
Measurement Methods
NIOSH 2514
See: NMAM or OSHA Methods
Personal Protection & Sanitation
Skin: Prevent skin contact
Eyes: Prevent eye contact
Wash skin: When contaminated
Remove: When wet or contaminated
Change: Daily
Provide: Quick drench
First Aid (See procedures)
Eye: Irrigate immediately
Skin: Soap wash immediately
Breathing: Respiratory support
Swallow: Medical attention immediately
Important additional information about respirator selection
Respirator Recommendations NIOSH/OSHA
Up to 5 mg/m3: (APF = 10) Any dust and mist respirator except single-use and quarter-mask respirators/(APF = 10) Any supplied-air respirator
Up to 12.5 mg/m3: (APF = 25) Any supplied-air respirator operated in a continuous-flow mode/(APF = 25) Any powered, air-purifying respirator with a dust and mist filter
Up to 25 mg/m3: (APF = 50) Any air-purifying, full-facepiece respirator with a high-efficiency particulate filter/(APF = 50) Any powered, air-purifying respirator with a tight-fitting facepiece and a high-efficiency particulate filter*/(APF = 50) Any self-contained breathing apparatus with a full facepiece/(APF = 50) Any supplied-air respirator with a full facepiece
Up to 50 mg/m3: (APF = 1000) Any supplied-air respirator operated in a pressure-demand or other positive-pressure mode*
Emergency or planned entry into unknown concentrations or IDLH conditions: (APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode/(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus
Escape: (APF = 50) Any air-purifying, full-facepiece respirator with a high-efficiency particulate filter/Any appropriate escape-type, self-contained breathing apparatus
Exposure Routes inhalation, skin absorption, ingestion, skin and/or eye contact
Symptoms Headache, dizziness; cyanosis; red blood cell Heinz bodies
Target Organs Blood, kidneys, liver, cardiovascular system, central nervous system
See also: INTRODUCTION   See ICSC CARD: 0971   See MEDICAL TESTS: 0015

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