NIOSH Pocket Guide to Chemical Hazards

Methyl parathion CAS 298-00-0
(CH3O)2P(S)OC6H4NO2 RTECS TG0175000
Synonyms & Trade Names
Azophos®; O,O-Dimethyl-O-p-nitrophenylphosphorothioate; Parathion methyl
DOT ID & Guide
2783 152
Exposure
Limits
NIOSH REL: TWA 0.2 mg/m3 [skin]
OSHA PEL†: none
IDLH N.D. See: IDLH INDEX Conversion
Physical Description
White to tan, crystalline solid or powder with a pungent, garlic-like odor. [pesticide] [Note: The commercial product in xylene is a tan liquid.]
MW: 263.2
BP: 289°F
MLT: 99°F
Sol(77°F): 0.006%
VP: 0.00001 mmHg
IP: ?

Sp.Gr: 1.36
Fl.P: ?
UEL: ?
LEL: ?

Combustible Solid
Incompatibilities & Reactivities
Strong oxidizers, water [Note: Explosive risk when heated above 122°F.]
Measurement Methods
NIOSH 5600; OSHA PV2112
See: NMAM or OSHA Methods
Personal Protection & Sanitation
Skin: Prevent skin contact
Eyes: Prevent eye contact
Wash skin: When contaminated/Daily
Remove: When wet or contaminated
Change: Daily
Provide: Eyewash, Quick drench
First Aid (See procedures)
Eye: Irrigate immediately
Skin: Soap wash immediately
Breathing: Respiratory support
Swallow: Medical attention immediately
Important additional information about respirator selection
Respirator Recommendations NIOSH
Up to 2 mg/m3: (APF = 10) Any chemical cartridge respirator with organic vapor cartridge(s) in combination with a dust, mist, and fume filter/(APF = 10) Any supplied-air respirator
Up to 5 mg/m3: (APF = 25) Any supplied-air respirator operated in a continuous-flow mode/(APF = 25) Any powered, air-purifying respirator with organic vapor cartridge(s) in combination with a dust, mist, and fume filter
Up to 10 mg/m3: (APF = 50) Any chemical cartridge respirator with a full facepiece and organic vapor cartridge(s) in combination with a high-efficiency particulate filter/(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister having a high-efficiency particulate filter/(APF = 50) Any powered, air-purifying respirator with a tight-fitting facepiece and organic vapor cartridge(s) in combination with a high-efficiency particulate filter/(APF = 50) Any supplied-air respirator that has a tight-fitting facepiece and is operated in a continuous-flow mode/(APF = 50) Any self-contained breathing apparatus with a full facepiece/(APF = 50) Any supplied-air respirator with a full facepiece
Up to 200 mg/m3: (APF = 2000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode
Emergency or planned entry into unknown concentrations or IDLH conditions: (APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode/(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus
Escape: (APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister having a high-efficiency particulate filter/Any appropriate escape-type, self-contained breathing apparatus
Exposure Routes inhalation, skin absorption, ingestion, skin and/or eye contact
Symptoms Irritation eyes, skin; nausea, vomiting, abdominal cramps, diarrhea, salivation; headache, dizziness, lassitude (weakness, exhaustion); rhinorrhea (discharge of thin mucus), chest tightness; blurred vision, miosis; cardiac irregularities; muscle fasciculation; dyspnea (breathing difficulty)
Target Organs Eyes, skin, respiratory system, central nervous system, cardiovascular system, blood cholinesterase
See also: INTRODUCTION   See ICSC CARD: 0626

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