NIOSH Pocket Guide to Chemical Hazards

Strychnine CAS 57-24-9
C21H22N2O2 RTECS WL2275000
Synonyms & Trade Names
Nux vomica, Strynchnos
DOT ID & Guide
1692 151
Exposure
Limits
NIOSH REL: TWA 0.15 mg/m3
OSHA PEL: TWA 0.15 mg/m3
IDLH 3 mg/m3 See: 57249 Conversion
Physical Description
Colorless to white, odorless, crystalline solid. [pesticide]
MW: 334.4
BP: Decomposes
MLT: 514°F
Sol: 0.02%
VP: Low
IP: ?

Sp.Gr: 1.36
Fl.P: ?
UEL: ?
LEL: ?

Combustible Solid, but difficult to ignite.
Incompatibilities & Reactivities
Strong oxidizers
Measurement Methods
NIOSH 5016
See: NMAM or OSHA Methods
Personal Protection & Sanitation
Skin: Prevent skin contact
Eyes: No recommendation
Wash skin: When contaminated
Remove: No recommendation
Change: Daily

First Aid (See procedures)
Eye: Irrigate immediately
Skin: Soap wash promptly
Breathing: Respiratory support
Swallow: Medical attention immediately
Important additional information about respirator selection
Respirator Recommendations NIOSH/OSHA
Up to 0.75 mg/m3: (APF = 5) Any dust and mist respirator
Up to 1.5 mg/m3: (APF = 10) Any dust and mist respirator except single-use and quarter-mask respirators/(APF = 10) Any supplied-air respirator
Up to 3 mg/m3: (APF = 25) Any supplied-air respirator operated in a continuous-flow mode/(APF = 25) Any powered, air-purifying respirator with a dust and mist filter/(APF = 50) Any air-purifying, full-facepiece respirator with a high-efficiency particulate filter/(APF = 50) Any self-contained breathing apparatus with a full facepiece/(APF = 50) Any supplied-air respirator with a full facepiece
Emergency or planned entry into unknown concentrations or IDLH conditions: (APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode/(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus
Escape: (APF = 50) Any air-purifying, full-facepiece respirator with a high-efficiency particulate filter/Any appropriate escape-type, self-contained breathing apparatus
Exposure Routes inhalation, ingestion, skin and/or eye contact
Symptoms Stiff neck, facial muscle; restlessness, anxiety, increased acuity of perception; increased reflex excitability; cyanosis; tetanic convulsions with opisthotonos
Target Organs central nervous system
See also: INTRODUCTION   See ICSC CARD: 0197   See MEDICAL TESTS: 0213

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