NIOSH Pocket Guide to Chemical Hazards

Warfarin CAS 81-81-2
C19H16O4 RTECS GN4550000
Synonyms & Trade Names
3-(alpha-Acetonyl)-benzyl-4-hydroxycoumarin, 4-Hydroxy-3-(3-oxo-1-phenyl butyl)-2H-1-benzopyran-2-one, WARF
DOT ID & Guide
Exposure
Limits
NIOSH REL: TWA 0.1 mg/m3
OSHA PEL: TWA 0.1 mg/m3
IDLH 100 mg/m3 See: 81812 Conversion
Physical Description
Colorless, odorless, crystalline powder. [rodenticide]
MW: 308.3
BP: Decomposes
MLT: 322°F
Sol: 0.002%
VP(71°F): 0.09 mmHg
IP: ?

Sp.Gr: ?
Fl.P: ?
UEL: ?
LEL: ?

Combustible Solid
Incompatibilities & Reactivities
Strong oxidizers
Measurement Methods
NIOSH 5002
See: NMAM or OSHA Methods
Personal Protection & Sanitation
Skin: Prevent skin contact
Eyes: No recommendation
Wash skin: When contaminated
Remove: When wet or contaminated
Change: Daily

First Aid (See procedures)
Eye: Irrigate immediately
Skin: Soap wash promptly
Breathing: Respiratory support
Swallow: Medical attention immediately
Important additional information about respirator selection
Respirator Recommendations NIOSH/OSHA
Up to 0.5 mg/m3: (APF = 5) Any dust and mist respirator
Up to 1 mg/m3: (APF = 10) Any dust and mist respirator except single-use and quarter-mask respirators/(APF = 10) Any supplied-air respirator
Up to 2.5 mg/m3: (APF = 25) Any supplied-air respirator operated in a continuous-flow mode/(APF = 25) Any powered, air-purifying respirator with a dust and mist filter
Up to 5 mg/m3: (APF = 50) Any air-purifying, full-facepiece respirator with a high-efficiency particulate filter/(APF = 50) Any supplied-air respirator that has a tight-fitting facepiece and is operated in a continuous-flow mode/(APF = 50) Any powered, air-purifying respirator with a tight-fitting facepiece and a high-efficiency particulate filter/(APF = 50) Any self-contained breathing apparatus with a full facepiece/(APF = 50) Any supplied-air respirator with a full facepiece
Up to 100 mg/m3: (APF = 1000) Any supplied-air respirator operated in a pressure-demand or other positive-pressure mode
Emergency or planned entry into unknown concentrations or IDLH conditions: (APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode/(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus
Escape: (APF = 50) Any air-purifying, full-facepiece respirator with a high-efficiency particulate filter/Any appropriate escape-type, self-contained breathing apparatus
Exposure Routes inhalation, skin absorption, ingestion, skin and/or eye contact
Symptoms Hematuria (blood in the urine), back pain; hematoma arms, legs; epistaxis (nosebleed), bleeding lips, mucous membrane hemorrhage; abdominal pain, vomiting, fecal blood; petechial rash; abnormal hematologic indices
Target Organs Blood, cardiovascular system
See also: INTRODUCTION   See ICSC CARD: 0821   See MEDICAL TESTS: 0242

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