Cluster
for Genes and Genome Systems
This cluster
supports studies on genomes and genetic mechanisms in all organisms,
whether prokaryote, eukaryote, phage, or virus. Proposals on the
structure, maintenance, expression, transfer, and stability of genetic
information in DNA, RNA, and proteins and how those processes are
regulated are appropriate. Areas of interest include genome organization,
molecular and cellular evolution, replication, recombination, repair,
and vertical and lateral transmission of heritable information.
Of equal interest are the processes that mediate and regulate gene
expression, such as chromatin structure, epigenetic phenomena, transcription,
RNA processing, editing and degradation, and translation. The use
of innovative in vivo and/or in vitro approaches, including biochemical,
physiological, genetic, genomic, and/or computational methods, is
encouraged, as is research at the interfaces of biology, physics,
chemistry, mathematics and computer science, and engineering.
This cluster
includes the scientific themes of eukaryotic genetics, microbial
genetics, and biochemistry of gene expression.
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