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Biological Sciences Advisory Committee Member

Vicki L. Chandler
Department of Plant Sciences
University of Arizona
303 Forbes Building
Tucson, Arizona 85721
chandler@ag.arizona.edu

EDUCATION:
1978 B.A., Biochemistry, University of California, Berkeley
1983 Ph.D., Biochemistry, University of California, San Francisco


PROFESSIONAL EXPERIENCE:

1997- present Full Professor, Dept. of Plant Sciences, University of Arizona, Tucson, AZ

1998-present Full Professor, Molecular Cellular Biology Dept., Univ. of Arizona, Tucson, AZ

1998-present Member, Interdisciplinary Program in Genetics, Univ. of Arizona, Tucson, AZ

1996-1997 Professor of Biology and Member, Institute of Molecular Biology, University of Oregon, Eugene, Oregon

1985-1996 Assistant and Associate Professor of Biology and Member, Institute of Molecular Biology, University of Oregon, Eugene, Oregon

1983-1985 Postdoctoral Fellow in Plant Biology, Laboratory of Dr. Virginia Walbot, Regulation of Mutator transposable elements in maize, Department of Biological Sciences, Stanford University

1978-1983 Predoctoral Trainee, Laboratory of Dr. Keith R. Yamamoto, Glucocorticoid regulation of mouse mammary tumor virus gene expression. Department of Biochemistry and Biophysics, University of California, San Francisco

1977 Summer Undergraduate Research Program. Laboratory of Dr. Raymond Gestland. Cold Spring Harbor Laboratory, Cold Spring Harbor, New York

1976-1978 Undergraduate Research and Senior Thesis.. Laboratory of Dr. R. Schekman Mating pheromone induction of chitin synthesis in the yeast cell wall. Department of Biochemistry, University of California, Berkeley.

HONORS/AWARDS:

1991 National Science Foundation, Faculty Awards for Women Scientists and Engineers
1988 Searle Scholar
1985-1990 Presidential Young Investigator Award
1983-1985 National Science Foundation Plant Biology Postdoctoral Fellowship
1981-1982 Chancellor's Graduate Research Fellow, U.C. San Francisco
1979-1981 NIH Predoctoral Trainee, U.C. San Francisco
1978-1979 University Scholarship Awardee, U.C. San Francisco
1976-1978 Recipient, Alumni Scholarships, U.C. Berkeley
1978 Recipient, Grace Faminari Award (Biochem. Depart. Award to top female undergraduate)
1977-1978 President's Undergraduate Research Fellowship Awardee, U.C. Berkeley

NATIONAL ADVISORY PANELS/ PROFESSIONAL EXPERIENCE:

NSF - Plant Biology Postdoctoral Fellowship Panel, 1987, 1988
DOE - Advisory Panel Biological Energy Research Program, 1987
Defense Science Study Group
NSF Advisory Committee, Arabidopsis genomic sequencing project, May 1989
NSF - Eukaryotic Genetics Panel, May 1989-1991
NIH - Special Reviewer Genetics Study Section 1991
NSF - Waterman Award Committee 1992-95
NIH - Special Reviewer Molecular Cytology Study Section 1993
NIH - Study Section-Genetic Training Grants 1993-1997
NSF - NYI Panel 1994
USDA - Plant Genetic Mechanisms Panel 1998
DOE, USDA, NSF Rice Genome Sequencing Panel 1999
NSF Plant Genome Initiative Panel 2000
Chair, Gordon Research Conference on Plant Molecular Biology 1994
Co-Chair and Co-Founder, Gordon Research Conference on Epigenetics 1995
Genetics Society of America, Board of Directors 1995-1997
Plant Physiology - Monitoring Editor 1995-1998
Plant Physiology - Associate Editor 1998-2001
Gordon Research Conferences, Elected Council Member 1996
Gordon Research Conferences, Elected Board of Trustees 1997-2002
Gordon Research Conferences, Elected Vice-Chair Board of Trustees 2000
Gordon Research Conferences, Elected Chair Board of Trustees 2001

Executive Committee, American Society Plant Physiologists (elected) 1998-2000
President-Elect, American Society Plant Physiologists 2000-2001
Associate Editor, Genetics 1999-present
International Society Plant Molecular Biology Board of Directors (elected) 1999-2003
Maize Genetics Executive Committee (elected) 2000-2003

Refereed Journal Articles past five years

Sainz, M.B., S.A. Goff and V.L. Chandler. Extensive mutagenesis of a transcriptional activation domain identifies single hydrophobic and acidic amino acids important for activation in vivo. Molecular Cell Biology 17(l): 115-122 (1997).

Sainz, M.B., Grotewold, E. and V.L. Chandler. Evidence for direct activation of an anthocyanin promoter by the maize Cl protein and comparison of DNA binding by related Myb domain proteins. Plant Cell 9: 61 1 625 (1997).

Lesnick, M.L., and V.L. Chandler. Activation of the maize anthocyanin gene a2 is mediated by an element conserved in many anthocyanin promoters. Plant Physiology 1 1 7: 43 7-445 (1998).

Selinger, D.A., D. Lisch and V.L. Chandler. The maize regulatory gene B-Peru contains a DNA rearrangement that specifies tissue-specific expression through both positive and negative promoter elements. Genetics 149: 1125-1138 (1998).

Hollick J.B and V.L. Chandler. Epigenetic allelic states of a maize transcriptional regulatory locus exhibit overdominant gene action. Genetics 150: 891-897 (1998).

Selinger, D.A. and V.L. Chandler. A mutation in the pale aleurone color I gene identifies a novel regulator of the maize anthocyanin pathway. Plant Cell 11: 5-14 (1999).

Selinger, D.A. and V.L. Chandler. Major recent and independent changes in the levels and patterns of expression have occurred at the b gene, a regulatory locus in maize. PNAS 96: 15007-15012 (1999).

Hollick, J.B., G.I. Patterson, I.M. Asmundsson, and V.L. Chandler. Paramutation alters regulatory control of the maize pl locus. Genetics 154: 1827-183 8 (2000).

Dorweiler, J., C. Carey, K. Kubo, J. Kermicle, J.B. Hollick and V.L. Chandler. Mediator ofparamutation I (mop]) is required for the establishment and maintenance of paramutation at multiple maize loci. Plant Cell 12: 2101-2118 (2000).

Grotewold, E., M.B. Sainz, L. Tagliani, J.M. Hernandez, B. Bowen and V.L. Chandler. Identification of the residues in the Myb domain of maize C I that specify the interaction with the BHLH cofactor R. Proc Natl Acad Sci 97: 13579-13584 (2000).

Holick, J.B. and V.L. Chandler. Genetic factors required to maintain repression of a parainutagenic maize pl] allele. Genetics 157: 369-378 (2001).

Selinger, D.A. and V.L. Chandler B-Bolivia, an allele of the maize bl gene with variable expression, contains a
high copy retrotransposon related sequence immediately upstream. Plant Physiology 125: 1363-1379.

Invited Review and Commentary Articles past 5 years

Chandler, V.L., K.M. Kubo, and J.B. Hollick. b and pl Paramutation in Maize: Heritable Transcription States Programmed During Development. In: "Epigenetics," (R. Martiennsen and V. Russo, eds.). Cold Spring Harbor Press, New York, pp. 289-304 (1996).

Hollick, J.B.., J.E. Dorweiler, and V.L. Chandler. Paramutation and Related Allelic Interactions. Trends Genet 13: 302-308 (1997).

Chandler, V.L., W.B. Eggleston, J. Dorweiler. Paramutation in maize. Plant Molecular Biology 43: 121-145
(2000).

Chandler, V.L. and R. Jorgensen. Silencing Morpheus Awakens Transgenes. Nature Biotech 18: 602-603 (2000).

Chandler, V.L. and H. Vaucheret. Gene Activation and Gene Silencing. Plant Physiology 125: 145-148 (2001).

Chandler, V.L., M. Stam and L. Sidorenko. Long distance cis and trans interactions mediate paramutation.
Advances Genetics, in press.

 

 
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