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National Academy of Sciences' Review of EPA's Draft Perchlorate Environmental Contamination: Toxicological Review and Risk Characterization

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In the interest of resolving scientific questions, the EPA, the Department of Defense, the Department of Energy, and the National Aeronautics and Space Administration - members of a broader Interagency Working Group on Perchlorate led by the Office of Science and Technology Policy - have referred scientific issues and EPA's 2002 Draft Health Assessment on Perchlorate to the National Academy of Sciences (NAS) for review. The NAS is the world's pre-eminent, deliberative society of distinguished scholars engaged in scientific research. The March 19, 2003, transmittal letter to the NAS, which includes the Charge developed by the Interagency Working Group on Perchlorate as an attachment, describes the scope and focus of its review. The first meeting of the NAS perchlorate review panel was held on October 27, 2003, in Washington, D.C.

Several pieces of information were provided to the NAS by EPA prior to the October 27th meeting and an EPA presentation was made at the meeting. This information is being made available to the public at this website. A description of the information is below.

  1. Disposition of Comments and Recommendations for Revision to "Perchlorate Environmental Contamination: Toxicological Review and Risk Characterization" (External Review Draft, January 16, 2002):
    EPA's 2002 External Review Draft perchlorate health and ecotoxicological risk assessment was submitted to an external expert peer panel for review. That panel's review generated comments (Peer Panel Report, June 2002). As part of the scientific process, EPA's National Center for Environmental Assessment submitted its responses to those 2002 peer panel recommendations and public comments to the NAS perchlorate panel.

  2. Compilation of Public Comments Received by the U.S. EPA on "Perchlorate Environmental Contamination: Toxicological Review and Risk Characterization" (2002 External Review Draft):
    This is a complete list of the comments received from the public and stakeholders on EPA's 2002 draft risk assessment report. Their full comments that were submitted to the Agency are included.

  3. References Associated with Disposition of Comments on the U.S. EPA's "Perchlorate Environmental Contamination: Toxicological Review and Risk Characterization" (2002 External Review Draft):
    This is a compilation of those studies and other materials referenced in EPA's disposition of comments report (see #1) that are not readily available in the published literature.

  4. Perchlorate Risk Characterization: US EPA Technical Perspective:
    At the first meeting of the NAS perchlorate panel on October 27, 2003, EPA made a presentation (PowerPoint format) on the Agency's 2002 draft health assessment that included some recommendations for revision.
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Citation:
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spacer National Academy of Sciences' Review of EPA's Draft Perchlorate Environmental Contamination: Toxicological Review and Risk Characterization.
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Additional Information:
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spacer Please note that we are making these documents available immediately in the interest of science. These documents may not currently be accessible to those requiring assistive technology devices. Questions concerning these documents may be addressed to the contact person referenced elsewhere on this page. As accessible versions of these documents become available we will replace the existing ones. The content and general nature of the documents will not be changed by the conversion.
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Contact Information:
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Annie M. Jarabek
by phone at:  919-541-4847
by fax at:  919-541-1818
or by email at:  jarabek.annie@epa.gov
Downloads:
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Bullet Item Disposition of Comments and Recommendations for Revisions to "Perchlorate Environmental Contamination: Toxicological Review and Risk Characterization External Review Draft (January 16, 2002)"
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Bullet Item Compilation of Public Comments Received By the U.S. EPA on "Perchlorate Environmental Contamination: Toxicological Review and Risk Characterization" (2002 External Review Draft)
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Bullet Item References Associated With Disposition of Comments on the U.S. EPA's "Perchlorate Environmental Contamination: Toxicological Review and Risk Characterization" (2002 External Review Draft)
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Bullet Item Charge to Reviewers and Accompanying Transmittal Letter from Paul Gilman, Ph. D.
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Bullet Item Federal Facilities Restoration and Reuse Office - Perchlorate Web Page
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Bullet Item Office of Ground Water and Drinking Water - Perchlorate Web Page
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Related Entries:
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Bullet Item The Effects of Ammonium Perchlorate on Thyroids
spacer Relationship Reason:   Related Document
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Bullet Item Perchlorate Environmental Contamination: Toxicological Review and Risk Characterization Based on Emerging Information (External Review Draft)
spacer Relationship Reason:   Previous 1998 External Review Draft
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Bullet Item Perchlorate Environmental Contamination: Toxicological Review and Risk Characterization (2002 External Review Draft)
spacer Relationship Reason:   Draft Assessment of Health and Ecotoxicological Effects of Perchlorate Which Was the Subject of the Peer Review.
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Bullet Item Report on the Peer Review of the U.S. Environmental Protection Agency's Draft External Review Document "Perchlorate Environmental Contamination: Toxicological Review and Risk Characterization"
spacer Relationship Reason:   Report on the Peer Review of the 2002 Draft Assessment
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Last Updated on Monday, July 26, 2004
URL: http://cfpub.epa.gov/ncea/cfm/recordisplay.cfm