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Display category headings
Research Project:
Integrated Management of Fish Health by Multi-Disciplinary Approaches
Location:
Aquatic Animal Health Research
Title: Control Y Prevencion DE Streptococcus En Peces Mediante Vacunacion
Authors
Submitted to: Book Chapter
Publication Acceptance Date: May 18, 2004
Publication Date: August 18, 2004
Citation: Klesius, P.H., Evans, J.J., Shoemaker, C.A. 2004. Control Y Prevencion DE Streptococcus En Peces Mediante Vacunacion. Book Chapter. Varela Editora E Livraria. Sao Paulo.
Interpretive Summary: The Gram-positive coccus, Streptococcus iniae, is among the most prominent causes of
septicaemic disease affecting both captive and wild fish in fresh, estuarine, and marine waters.
This coccus is highly virulent for more than 27 species of fish, worldwide. Resistance to
antibiotics, refusal of sick fish to eat mediated (medicated?) feed, and the rapid onset of mortality
make the inadequate antibiotic therapies. Vaccination is the best means of preventing
streptococcosis. Vaccines against S. iniae have been successfully developed and employed in
fish production systems. The vaccines consist of either formalin-killed S. iniae cells alone
(bacterin) or combined with extra-cellular components (modified bacterin). Mixing The addition
of an adjuvant into the bacterins may extent their effectiveness. Bacterins are administrated by
injection and provide protective immunity between 4 and 6 months. Specific serum antibodies
against S. iniae is produced following the administration of the and appears to be responsible
for the protective immune responses. This antibody alone or aided by complement may kill the
streptococcal cells either in the presence of absence of phagocytic or natural cytotoxic cells.
The well being of fish calls for prevention of infection by vaccination, quarantine of new
arrivals, health and water quality monitoring, management of husbandry stress, and a routinist
disinfection of facilities and equipment on an as used basis. Adoption of such a health
management plan is a much more cost-effective alternative to depopulating and fallowing a
highly infected production facility.
Technical Abstract: Abstract
The Gram-positive coccus, Streptococcus iniae, is among the most prominent causes of
septicaemic disease affecting both captive and wild fish in fresh, estuarine, and marine waters.
This coccus is highly virulent for more than 27 species of fish, worldwide. Resistance to
antibiotics, refusal of sick fish to eat mediated (medicated?) feed, and the rapid onset of mortality
make the inadequate antibiotic therapies. Vaccination is the best means of preventing
streptococcosis. Vaccines against S. iniae have been successfully developed and employed in
fish production systems. The vaccines consist of either formalin-killed S. iniae cells alone
(bacterin) or combined with extra-cellular components (modified bacterin). Mixing The addition
of an adjuvant into the bacterins may extent their effectiveness. Bacterins are administrated by
injection and provide protective immunity between 4 and 6 months. Specific serum antibodies
against S. iniae is produced following the administration of the and appears to be responsible
for the protective immune responses. This antibody alone or aided by complement may kill the
streptococcal cells either in the presence of absence of phagocytic or natural cytotoxic cells.
The well being of fish calls for prevention of infection by vaccination, quarantine of new
arrivals, health and water quality monitoring, management of husbandry stress, and a routinist
disinfection of facilities and equipment on an as used basis. Adoption of such a health
management plan is a much more cost-effective alternative to depopulating and fallowing a
highly infected production facility.
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Project Team |
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Klesius, Phillip
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Welker, Thomas
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Panangala, Victor
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Yeh, Hung-Yueh
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Bader, Joel
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Lim, Chhorn
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Shelby, Richard
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Xu, Dehai
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Delaney, Mary
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Evans, Joyce
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Shoemaker, Craig
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Publications
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