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Toxic Chemicals in Tobacco Products

Cigarette smoking is a major cause of lung cancer, the leading cause of cancer death in both men and women in the United States. Worldwide, lung cancer kills over one million people each year2. Tobacco smoke contains over 60 carcinogens3. These chemicals represent approximately 7 chemical classes (polycyclic aromatic hydrocarbons, arenes, N-nitrosamines, aromatic and heterocyclic aromatic amines, aldehydes, organic compounds, and inorganic compounds). The 2000 Surgeon General's Report has concluded that smokers receive very little information regarding chemical constituents when they purchase a tobacco product.1 Read about CDC research to measure toxic chemicals in tobacco or tobacco smoke, plus the chemical levels in popular tobacco products.
 

References

  1. Adams JD, Lee SJ, Vinchkoski N, Castonguay A, Hoffmann D. 1983. On the formation of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone during smoking. Cancer Lett. 17(3):339-346.

  2. Hecht SS. 1999. Tobacco Smoke Carcinogens and Lung Cancer. JNCI 91(14):1194-1210.

  3. Hoffmann D, Hoffmann I, and El-Bayoumy K. 2001. The less harmful cigarette: A controversial issue. A tribute to Ernst L. Wynder. Chem. Res. Toxicol. 14(7):767-790.

  4. Hoffmann D, Brunnemann KD, Prokopczyk B, Djordjevic M. 1994. Tobacco-specific N-nitrosamines and Areca-derived N-nitrosamines: Chemistry, biochemistry, carcinogenicity, and relevance to humans. J Toxicol Environ Health. 41:1-52.


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This page last reviewed September 12, 2003

United States Department of Health and Human Services
Centers for Disease Control and Prevention
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