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Display category headings
Research Project:
Fish Health: Bacterial Genomics Research for Vaccine Development
Location:
Aquatic Animal Health Research
Project Number: 6420-32000-012-03
Project Type:
Specific C/A
Start Date: Apr 28, 2000
End Date: Feb 28, 2005
Objective:
The objectives of this project are to work with the Department of Fisheries and Allied Aquacultures of Auburn University to conduct research to characterize genomic sequences from fish pathogenic bacteria for prediction of genes that may encode diagnostic and vaccine candidates. Further the work includes epidemiological and diagnostic and vaccine candidates. Further the work includes epidemiological and pathogenic research related to major fish health problems of catfish and tilapia.
Approach:
Work closely with Department of Fisheries and Allied Aquacultures of Auburn University to conduct the genomic research, collecting, analyzing and reporting on data. By applying appropriate tools of genomic technologies to the sequences of candidate bacterial pathogens, it is possible to identify putative diagnostic and vaccine candidates. The major pathogenic bacteria to be be sequenced include Edwardsiella ictaluri, Flavobacterium columnare and Streptococcus iniae. The utilization of genomic sequence in combination with the application of bioinformatics through genomics and proteomics can expedite the diagnostic and vaccine discovery process by rapidly providing sets of potential candidates for further testing. Epidemiological and pathological research will also be conducted by application of diagnostic tests and field evaluation of fish pathogen problems.
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