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Alternative names Return to top
Perforation of the esophagusDefinition Return to top
An esophageal perforation is a hole in the esophagus, the tube through which food passes from the mouth to the stomach.
Causes, incidence, and risk factors Return to top
The esophagus is a muscular tube that serves as a conduit for the passage of food and fluid from the mouth to the stomach. Perforation is the presence of a hole through which the contents of the esophagus can pass into the mediastinum (the surrounding area in the chest). This often results in infection of the mediastinum or mediastinitis.
The most common cause (more than 75%) of esophageal perforation is injury during a medical procedure such as esophagoscopy (a procedure to examine the esophagus) or placement of a naso-gastric tube.
The esophagus may also become perforated as the result of a disease process such as a tumor or gastric reflux with ulceration, a mechanical problem such as violent retching, or ingestion of a foreign body or caustic agents.
Still less common causes include injuries from penetrating or blunt trauma or injury to the esophagus during an operation on another organ near the esophagus. Cases have also very rarely been associated with childbirth, defecation, seizures, heavy lifting, and forceful swallowing.
Symptoms Return to top
The main symptom is pain at first, but the condition can progress to shock -- even death -- if untreated.
For patients with perforation of the uppermost portion of the esophagus, neck pain or stiffness and air bubbles underneath the skin may be present.
For patients with perforation of the mid-portion or lower-most portion of the esophagus, difficulty swallowing, chest pain and difficulty breathing may be present.
Signs and tests Return to top
Signs include fast breathing, rapid heart rate, low blood pressure and fever. A chest x-ray may demonstrate air in the soft tissues of the chest, fluid that has leaked from the esophagus into the space around the lungs, or collapse of the lung.
A chest CT scan may demonstrate formation of an abscess in the chest or evidence of esophageal cancer. A water-soluble contrast swallow (motion picture x-rays after drinking dye) may show the location of the perforation.
Treatment Return to top
The treatment can be divided into initial and definitive phases. Early surgery is appropriate for almost all patients. Every effort should be made to have surgery within 24 hours of the occurrence of the perforation.
The initial phase includes diagnostic studies to determine the location and cause of the hole, administration of IV fluids, and administration of IV antibiotics to prevent or treat infection. Fluid that has collected around the lungs may be treated with a chest tube to drain it away.
Repair of the perforation is the definitive treatment. For some patients with perforation in the uppermost (neck region) of the esophagus, the perforation may heal by itself if the patient does not eat or drink for a period of time. In this case, nutrition must be provided by another source such as a stomach feeding tube.
For perforation in the mid-portion and lower-most portions of the esophagus, an operation is usually required for repair. Depending on the size and location of the perforation, the leak may be treated by simple repair or by removal of the esophagus.
Expectations (prognosis) Return to top
For patients with an early diagnosis (less than 24 hours), the prognosis is good. The survival rate is 90% when surgery is accomplished within 24 hours. This rate drops to about 50% when treatment is delayed, however.Complications Return to top
Possible complications include:
Calling your health care provider Return to top
Demand immediate medical attention if you are in the hospital. If not, go to the emergency room or call the local emergency number (such as 911) if you have recently had surgery or the placement of a tube in the esophagus and have pain, difficulty swallowing or breathing, or have other reason to suspect you may have esophageal perforation. Time is of the essence in treating this condition.
Prevention Return to top
Because of their nature, these injuries are difficult to prevent.
Update Date: 7/14/2004 Updated by: Norman S. Kato, MD, Surgeon with the Cardiac Care Medical Group, Encino, CA. Review provided by VeriMed Healthcare Network.
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Page last updated: 28 October 2004 |