Skip navigation | ||
|
||
Medical Encyclopedia |
|
Other encyclopedia topics: | A-Ag Ah-Ap Aq-Az B-Bk Bl-Bz C-Cg Ch-Co Cp-Cz D-Di Dj-Dz E-Ep Eq-Ez F G H-Hf Hg-Hz I-In Io-Iz J K L-Ln Lo-Lz M-Mf Mg-Mz N O P-Pl Pm-Pz Q R S-Sh Si-Sp Sq-Sz T-Tn To-Tz U V W X Y Z 0-9 |
Contents of this page: | |
|
Definition Return to top
Methemoglobinemia is a condition in which the iron in the hemoglobin molecule (the red blood pigment) is defective, making it unable to carry oxygen effectively to the tissues.Causes, incidence, and risk factors Return to top
There are two forms of inheritable methemoglobinemia, Type I and Type II.
Most hereditary cases are Type II, and result from a deficiency in the enzyme cytochrome b5 reductase. The other inheritable type, called hemoglobin M disease (Type I), is an autosomal dominant condition (you only need one affected parent to inherit it) characterized by an inability to convert methemoglobin back to hemoglobin. This usually causes few problems.
Exposure to certain chemicals may also cause an increase in the production of methemoglobin. These chemicals include nitrites (used commonly to prevent spoilage of meat), xylocaine, and benzene.
Symptoms Return to top
Signs and tests Return to top
Treatment Return to top
Medications used to treat this disorder include:Complications Return to top
In acute exposure:
Calling your health care provider Return to top
Call your health care provider if there is a family history of methemoglobinemia and you develop symptoms of this disorder.
Call your health care provider or emergency services immediately if there is severe shortness of breath.
Prevention Return to top
Genetic counseling is recommended for prospective parents with a family history of methemoglobinemia. Update Date: 8/18/2003 Updated by: David Webner, M.D., Sports Medicine Fellow, Crozer-Keystone Family Practice Program, Springfield, PA. Review provided by VeriMed Healthcare Network.
Home | Health Topics | Drug Information | Encyclopedia | Dictionary | News | Directories | Other Resources | |
Copyright | Privacy | Accessibility | Selection Guidelines U.S. National Library of Medicine, 8600 Rockville Pike, Bethesda, MD 20894 National Institutes of Health | Department of Health & Human Services |
Page last updated: 28 October 2004 |