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Definition Return to top
Bullous pemphigoid is a skin disorder characterized by large blisters.Causes, incidence, and risk factors Return to top
The blisters of bullous pemphigoid usually appear on the areas of the body that flex or move (flexural areas). About one-third of persons with bullous pemphigoid also develop blisters in the mouth. The disorder may occur in various forms, from no symptoms, to mild redness and irritation, to multiple blisters. The cause is not known, but may be related to immune system disorders.Symptoms Return to top
Signs and tests Return to top
A skin lesion biopsy shows a characteristic blistering pattern. A special type of skin biopsy may also be performed and examined by direct immunofluorescence. Some physicians may additionally order blood tests to help confirm the diagnosis.Treatment Return to top
Treatment is focused on relief of symptoms and prevention of infection.Expectations (prognosis) Return to top
Bullous pemphigoid usually responds well to treatment. In most patients, all medications may be stopped after several years. In a small group, however, the disease will recur after treatment is stopped.Complications Return to top
Infection of the skin lesions is the most common complication.Calling your health care provider Return to top
Call your physician if you notice unexplained blisters on your skin, or, an itchy rash persists despite home treatment.
Update Date: 8/15/2003 Updated by: Michael Lehrer, M.D., Department of Dermatology, University of Pennsylvania Medical Center, Philadelphia, PA. Review provided by VeriMed Healthcare Network.
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Page last updated: 28 October 2004 |