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Alternative names Return to top
AMP; Dermatan sulfate - urine; Urine heparan sulfate; Urine dermatan sulfate; Heparan sulfate - urineDefinition Return to top
This is a test that measures the amount of mucopolysaccharides excreted in the urine over a 24-hour period.How the test is performed Return to top
A 24-hour urine sample is needed.How to prepare for the test Return to top
No special preparation is needed. Drink a normal volume of fluids, and consume a normal diet.How the test will feel Return to top
The test involves only normal urination, and there is no discomfort.Why the test is performed Return to top
This test is performed to detect a rare disorder of excess acid mucopolysaccharides accumulation (especially dermatan sulfate and heparan sulfate) in the tissues. The severe form of this disorder can lead to Hurler's syndrome. Typically this test is only ordered for infants where there is a family history of mucopolysaccharidosis.Normal Values Return to top
Normal acid mucopolysaccharide values vary with age, and the normal range of values varies among laboratories. The laboratory performing the test should be consulted for interpretation of the test result.What abnormal results mean Return to top
Abnormally high levels of acid mucopolysaccharides reliably indicate mucopolysaccharidosis, and further detailed studies can identify which enzyme is defective.What the risks are Return to top
There are no risks (except for the chance of inaccurate results if all of the urine is not collected during the 24-hour period).Special considerations Return to top
If the test was performed on an infant, remove all remaining collection-device adhesive from the skin with warm soap and water. Update Date: 9/3/2003 Updated by: Michael C. Milone, M.D., Ph.D., Department of Pathology and Laboratory Medicine, University of Pennsylvania Medical Center, Philadelphia, PA. Review provided by VeriMed Healthcare Network.
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Page last updated: 28 October 2004 |