MedlinePlus Medical Encyclopedia: Herpes viral culture of lesion

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Herpes viral culture of lesion

Contents of this page:
Illustrations Alternative names Definition How the test is performed How to prepare for the test How the test will feel	Why the test is performed Normal Values What abnormal results mean What the risks are Special considerations

Illustrations

Viral lesion culture

Alternative names Return to top

Culture - herpes simplex virus; Herpes simplex virus culture

Definition Return to top

Herpes viral culture of a lesion is a test to confirm herpes simplex virus present in a skin lesion.

How the test is performed Return to top

A specimen from a skin lesion (often a genital lesion) is collected during the acute stage of symptomatic infection and placed in a special transport medium. The specimen may be placed in cell cultures to replicate for identification, or it may be identified by monoclonal antibodies that detect early antigens of herpes simplex virus.

Serotyping of the virus (type 1 or 2) may also be done. Results are available within 16 hours to 7 days of receipt of the specimen, depending on the culture method used.

How to prepare for the test Return to top

The specimen must be collected during an acute infection.

Infants and children:
The preparation you can provide for this test depends on your child's age, previous experiences, and level of trust. For general information regarding how you can prepare your child, see the following topics:

Infant test or procedure preparation (birth to 1 year)
Toddler test or procedure preparation (1 to 3 years)
Preschooler test or procedure preparation (3 to 6 years)
Schoolage test or procedure preparation (6 to 12 years)
Adolescent test or procedure preparation (12 to 18 years)

How the test will feel Return to top

The specimen is collected by scraping the suspected skin lesion or aspirating fluid from the lesion. This can cause a scraping or sticking sensation. Sometimes a specimen from the throat or eyes is obtained, usually by rubbing a sterile swab against the tissues.

Why the test is performed Return to top

The test is performed to confirm herpes simplex infection. The diagnosis is often made by clinical examination rather than diagnostic testing.

Normal Values Return to top

No growth is normal.

What abnormal results mean Return to top

Abnormal results may indicate active infection with herpes simplex virus or asymptomatic viral shedding.

Herpes genitalis (genital herpes simplex) is an additional condition under which the test may be performed.

What the risks are Return to top

The risks are slight bleeding or infection at the skin lesion site.

Special considerations Return to top

Viral culture for herpes is a poor test and is often falsely negative (but extremely rarely falsely positive). The absence of a positive culture does not confirm that the patient does not have herpes.

Update Date: 1/26/2004

Updated by: Daniel Levy, M.D., Ph.D., Infectious Diseases, Greater Baltimore Medical Center, Baltimore, MD. Review provided by VeriMed Healthcare Network.

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