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Alternative names Return to top
Consumption coagulopathyDefinition Return to top
DIC is a disorder of the "clotting cascade." It results in depletion of clotting factors in the blood.Causes, incidence, and risk factors Return to top
DIC is when your body's blood clotting mechanisms are activated throughout the body instead of being localized to an area of injury. Small blood clots form throughout the body, and eventually the blood clotting factors are used up and not available to form clots at sites of real tissue injury. Clot dissolving mechanisms are also increased.
This disorder has variable effects, and can result in either clotting symptoms or, more often, bleeding. Bleeding can be severe. DIC may be stimulated by many factors. These include infection in the blood by bacteria or fungus, severe tissue injury (as in burns and head injury), cancer, reactions to blood transfusions, and obstetrical complications (such as retained placenta after delivery).
Risk factors are recent sepsis, recent injury or trauma, recent surgery or anesthesia, complications of labor and delivery, leukemia or disseminated cancer, recent blood transfusion reaction, and severe liver disease.
Symptoms Return to top
Signs and tests Return to top
Treatment Return to top
The goal is to determine the underlying cause of DIC and provide treatment for that.Expectations (prognosis) Return to top
The underlying disease that causes the disorder will usually predict the probable outcome.Complications Return to top
Calling your health care provider Return to top
Go to the emergency room or call 911 if you have continued bleeding of unknown cause.Prevention Return to top
Get prompt treatment for conditions known to precipitate the disorder. Update Date: 6/5/2003 Updated by: Ezra E. W. Cohen, M.D., Section of Hematology/Oncology, Department of Medicine, The University of Chicago, Chicago, IL. Review provided by VeriMed Healthcare Network.
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Page last updated: 28 October 2004 |