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Definition Return to top
Atrial myxoma is a cardiac tumor involving the connective tissue within the heart's upper chambers (atria). The tumor may be located in the right or left atrium. (See also Atrial myxoma - left.)Causes, incidence, and risk factors Return to top
Most tumors in the heart are caused by the spread (metastasis) of cancerous cells from other tumors. Tumors originating in the heart (primary tumors of the heart) are rare. Of the primary cardiac tumors, myxomas are the most common.
Women are more likely to be affected than men. Some atrial myxomas are inherited. Family history is a risk factor.
About 75% of cardiac myxomas are in the left atrium (atrial myxoma - left), and the rest are in the right atrium. Right atrial myxomas are sometimes associated with tricuspid stenosis and atrial fibrillation.
Symptoms Return to top
Right atrial myxomas rarely produce symptoms until they have grown to be at least 13 cm (about 5 inches) in diameter. Symptoms may occur at any time, although they typically accompany changes in body position. Symptoms may include the following:
Other possible symptoms include:
Signs and tests Return to top
You may have signs of right-sided heart failure such as swollen legs or abdomen or distended neck veins. Examination of the heart with a stethoscope (auscultation) may reveal a "tumor plop" (a sound related to movement of the tumor) or other abnormal sounds.
Some of the symptoms and signs in right atrial myxoma may be caused by tricuspid stenosis (an obstruction of the valve that separates the right atrium and the right ventricle).
Right atrial myxoma may show on these tests:
An ECG may show atrial fibrillation. A CBC may show anemia and increased WBCs (white blood cells). The erythrocyte sedimentation rate (ESR) is increased.
Treatment Return to top
The only effective treatment is surgical removal of the tumor.Expectations (prognosis) Return to top
The probable outcome is poor without treatment. Although a myxoma is a benign tumor, tumor cells can break off and travel through the bloodstream to the lungs, producing pulmonary embolism.
Local growth of the tumor can obstruct blood flow through the heart, producing the symptoms and signs of tricuspid stenosis.
Complications Return to top
Calling your health care provider Return to top
Call your health care provider if you have any symptoms of atrial myxoma.Prevention Return to top
Awareness of risk related to family history can make early detection and treatment possible. Update Date: 7/20/2004 Updated by: Andrea A. Berger, M.D., Department of Cardiology, University of Pittsburgh Medical Center, Pittsburgh, PA. Review provided by VeriMed Healthcare Network.
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Page last updated: 28 October 2004 |