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Alternative names Return to top
LAP - urine; Urine LAPDefinition Return to top
This is a test that measures the amount of leucine aminopeptidase (LAP) in urine.How the test is performed Return to top
A 24-hour urine sample is needed. The health care provider will instruct you, if necessary, to discontinue drugs that may interfere with the test (see special considerations).For an infant, thoroughly wash the area around the urethra. Open a urine collection bag (a plastic bag with an adhesive paper on one end), and place it on your infant. For males, the entire penis can be placed in the bag and the adhesive attached to the skin. For females, the bag is placed over the labia. Place a diaper over the infant (bag and all).
The infant should be checked frequently and the bag changed after the infant has urinated into the bag. For active infants, this procedure may take a couple of attempts -- lively infants can displace the bag, causing an inability to obtain the specimen. The urine is drained into the container for transport to the laboratory.
Deliver it to the laboratory or your health care provider as soon as possible upon completion.
How to prepare for the test Return to top
No special preparation is necessary for this test, but if the collection is being taken from an infant, a couple of extra collection bags may be necessary.How the test will feel Return to top
The test involves only normal urination, and there is no discomfort.Why the test is performed Return to top
Unlike other liver enzymes, LAP can be measured in the urine. This test may be appropriate in some cases as a screening test or to avoid the risks of having blood drawn. This test is performed much less commonly than the LAP blood test (leucine aminopeptidase - serum).Normal Values Return to top
Normal values range from 2-18 units per 24 hours.What abnormal results mean Return to top
Elevated levels of LAP can be seen in several conditions:
What the risks are Return to top
There is essentially no risk.Special considerations Return to top
Drugs that can affect LAP measurements include estrogens and progesterones (see Progestins - oral). Update Date: 2/9/2004 Updated by: Frank A. Greco, M.D., Ph.D., Director, Biophysical Laboratory, The Lahey Clinic, Burlington, MA. Review provided by VeriMed Healthcare Network.
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Page last updated: 28 October 2004 |