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Stool guaiac test

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Alternative names   

Guaiac smear test; Fecal occult blood test - guaiac smear; Stool occult blood test - guaiac smear

Definition    Return to top

The stool guiac test is a test that detects the presence of hidden (occult) blood in the stool (bowel movement). The stool guaiac is the most common form of fecal occult blood test (FOBT) in use today.

Brand names include Hemoccult, Hemoccult SENSA, ColoScreen, ColoScreen-ES, Seracult, and Seracult PlusĀ®.

How the test is performed    Return to top

A stool sample from three consecutive bowel movements is collected, smeared on a card, and mailed to a laboratory for processing. In order to ensure the accuracy of the guaiac test, it is important to follow, whenever available, the manufacturer's instruction on how to collect the stool.

Adults and children:
There are many ways to collect the samples. You can catch the stool on plastic wrap that is loosely placed over the toilet bowl and held in place by the toilet seat. Then put the sample in a clean container. One test kit supplies a special toilet tissue that you use to collect the sample, then put the sample in a clean container. Do not sample stool specimen from within the toilet bowl water, as this can cause measurement errors.

Infants and young children:
For children wearing diapers, you can line the diaper with plastic wrap. If the plastic wrap is positioned so that it isolates the stool from any urine output, mixing of urine and stool can be prevented for a better sample.

Laboratory procedures may vary. In one type of test, a small sample of stool is placed on a paper card. A drop or two of testing solution is applied to the opposite side of the card. A color change indicates the presence of blood in the stool.

How to prepare for the test    Return to top

Do not consume red meat, any blood-containing food, cantaloupe, uncooked broccoli, turnip, radish, or horseradish for 3 days prior to the test.

You may need to discontinue drugs that can interfere with the test such as vitamin C and aspirin if possible. Check with your health care provider regarding medication changes that may be necessary. Never discontinue or decrease any medication without consulting your health care provider.

How the test will feel    Return to top

Because this test involves normal bowel functions, there is no discomfort.

Why the test is performed    Return to top

This test is a screening test to detect blood in the gastrointestinal tract.

Normal Values    Return to top

A negative test result is normal.

What abnormal results mean    Return to top

Abnormal results may indicate:

Additional non-GI related causes of positive guaiac test may include:

Abnormal tests require follow-up with your physician.

What the risks are    Return to top

There can be false-positive and false-negative results. Using proper stool collection technique, avoiding certain drugs, and observing dietary restrictions can minimize these measurement errors.

Update Date: 2/10/2003

Updated by: Andrew J. Muir, M.D., M.H.S., Division of Gastroenterology, Duke University Medical Center, Durham, NC. Review provided by VeriMed Healthcare Network.

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