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Alternative names Return to top
Anti-streptolysin O titerDefinition Return to top
This is a blood test to measure anti-streptolysin O (ASO) antibodies.How the test is performed Return to top
Blood is drawn from a vein, usually on the inside of the elbow or the back of the hand. The puncture site is cleaned with antiseptic, and an elastic band is placed around the upper arm to apply pressure and restrict blood flow through the vein. This causes veins below the band to fill with blood.
A needle is inserted into the vein, and the blood is collected in an air-tight vial or a syringe. During the procedure, the band is removed to restore circulation. Once the blood has been collected, the needle is removed, and the puncture site is covered to stop any bleeding.
The blood is then sent to the laboratory for analysis.
How to prepare for the test Return to top
Fast for 6 hours before the test. Interfering factors such as high levels of beta lipoproteins can affect the test results.How the test will feel Return to top
When the needle is inserted to draw blood, some people feel moderate pain, while others feel only a prick or stinging sensation. Afterward, there may be some throbbing.Why the test is performed Return to top
This test is used to detect prior infection by Group A Streptococcus, the bacterium responsible for diseases such as glomerulonephritis, rheumatic fever, bacterial endocarditis, and scarlet fever.
ASO testing demonstrates the presence of antibodies generated by the body against the enzyme streptolysin O, which is produced by the bacteria and which causes destruction of red blood cells. The ASO antibody may be detected in the blood for weeks or months after the primary infection has been eradicated.
Normal Values Return to top
The ASO level is usually less than 160 Todd units per milliliter.What abnormal results mean Return to top
Elevated levels may indicate:What the risks are Return to top
Special considerations Return to top
Veins and arteries vary in size from one patient to another and from one side of the body to the other. Obtaining a blood sample from some people may be more difficult than from others. Update Date: 9/3/2003 Updated by: Michael C. Milone, M.D., Ph.D., Department of Pathology and Laboratory Medicine, University of Pennsylvania Medical Center, Philadelphia, PA. Review provided by VeriMed Healthcare Network.
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Page last updated: 28 October 2004 |