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Alternative names Return to top
Sweat test; Sweat chloride; Iontophoretic sweat testDefinition Return to top
This is a test that measures the level of chloride in sweat.How the test is performed Return to top
A low-level electric current is applied to the test area. The positive electrode is covered by gauze and saturated with pilocarpine (a drug that stimulates sweating). The negative electrode is covered with gauze and saturated with bicarbonate solution.
A current is applied for 5 to 12 minutes, and a paper disk is then placed over the test site and covered with paraffin to obtain an airtight seal. After 1 hour, the disk is transferred to a weighing jar, then put in water to dissolve the salts. This solution is then analyzed for chloride.
How to prepare for the test Return to top
No special preparation is necessary.How the test will feel Return to top
The test does not cause any discomfort.Why the test is performed Return to top
Children with cystic fibrosis have increased sodium and chloride concentrations in their sweat. The test may be performed on infants to determine if early therapy is needed.Normal Values Return to top
Normal values are as follows:
What abnormal results mean Return to top
An abnormal test may indicate the presence of cystic fibrosis. Update Date: 1/20/2004 Updated by: John Goldenring, M.D., M.P.H., Department of Pediatrics, Children's Hospital, San Diego, CA. Review provided by VeriMed Healthcare Network.
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Page last updated: 28 October 2004 |