MedlinePlus Medical Encyclopedia: Nasal mucosal biopsy

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Nasal mucosal biopsy

Contents of this page:
Illustrations Alternative names Definition How the test is performed How to prepare for the test How the test will feel	Why the test is performed Normal Values What abnormal results mean What the risks are Special considerations

Illustrations

Sinuses

Throat anatomy

Nasal biopsy

Alternative names Return to top

Biopsy - nasal mucosa; Nose biopsy

Definition Return to top

A nasal mucosal biopsy is a diagnostic procedure in which a small piece of tissue is removed from the mucosal lining of the nose.

How the test is performed Return to top

A topical anesthetic is sprayed into the nose (in some cases injection of local anesthesia may be required). A small piece of the tissue that appears abnormal is removed and sent to the laboratory for analysis.

How to prepare for the test Return to top

No special preparation is necessary, although fasting for a few hours may be advisable.

Infants and children:
The physical and psychological preparation you can provide for this or any test or procedure depends on your child's age, interests, previous experiences, and level of trust. For specific information regarding how you can prepare your child, see the following topics as they correspond to your child's age:

infant test or procedure preparation (birth to 1 year)
toddler test or procedure preparation (1 to 3 years)
preschooler test or procedure preparation (3 to 6 years)
schoolage test or procedure preparation (6 to 12 years)
adolescent test or procedure preparation (12 to 18 years)

How the test will feel Return to top

There may be some pressure or tugging sensations during removal of the specimen. After the anesthetic wears off, the area may be sore for a few days.

Why the test is performed Return to top

Nasal mucosal biopsy is most often performed when abnormal tissue is observed during examination of the nose or when disorders affecting the nasal mucosal tissue are suspected.

Normal Values Return to top

There is normal mucosal tissue, with no abnormal growths or tissues.

What abnormal results mean Return to top

necrotizing granuloma (granular tumor)
Wegener's disease
nasal polyps
nasal tumors (benign or malignant)
sarcoid
infections (tuberculosis, fungal)

What the risks are Return to top

infection
bleeding from the biopsy site

Special considerations Return to top

Avoid blowing your nose after the biopsy.

Update Date: 10/27/2003

Updated by: James L. Demetroulakos M.D. F.A.C.S., Department Of Otolaryngology, North Shore Medical Center, Salem, MA. Clinical Instructor in Otology and Laryngology Harvard Medical School. Review provided by VeriMed Healthcare Network.

The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed physician should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. Copyright 2002 A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.