Appendix A: project index

Study #

Study Title

Department of Defense

DoD-1

Naval Health Study Program

DoD-1A

Epidemiologic Studies of Morbidity Among Gulf War Veterans: A Search for Etiologic Agents and Risk Factors; Study 1: A Study of Symptoms Among 1500 Seabees

DoD-1B

Epidemiologic Studies of Morbidity Among Gulf War Veterans: A Search for Etiologic Agents and Risk Factors; Study 2: A comparative study of hospitalizations among Active-duty personnel who participated in the Gulf War and similar personnel who did not.

DoD-1C

Epidemiologic Studies of Morbidity Among Gulf War Veterans: A Search for Etiologic Agents and Risk Factors; Study 3: A comparative study of pregnancy outcomes among Gulf war veterans and other active-duty personnel.

DoD-1D

Epidemiologic Studies of Morbidity Among Gulf War Veterans: A Search for Etiologic Agents and Risk Factors; Study 4: Adverse Reproductive Outcomes in Gulf War Veterans

DoD-1E

Epidemiologic Studies of Morbidity Among Gulf War Veterans: A Search for Etiologic Agents and Risk Factors; Study 5: Seabee Health Study.

DoD-1F

Epidemiologic Studies of Morbidity Among Gulf War Veterans: A Search for Etiologic Agents and Risk Factors; Study 6: A Comparison of Nonfederal Hospitalization Experience Among Veterans in California who have separated from active service: PGW vs. EV.

DoD-1G

Epidemiologic Studies of Morbidity Among Gulf War Veterans: A Search for Etiologic Agents and Risk Factors; Study 7: Prevalence of Congenital Anomalies Among Children of Persian Gulf War Veterans.

DoD-2

Physiological and Neurobehavioral Effects in Rodents from Exposure to Pyridostigmine, Fuels, and DEET

DoD-4

The General Well-Being of Gulf War Era Service Personnel from the States of Pennsylvania and Hawaii: A Survey

DoD-6

Program DoD-6

DoD-6A

Combat Stress Pharmacotherapy

DoD-6B

Combat Stress Diagnosis, PTSD Prevention

DoD-7A

Health Risk Assessment of Embedded Depleted Uranium: Behavior, Physiology, Histology, and Biokinetic Modeling

DoD-7B

Carcinogenicity of Depleted Uranium Fragments

DoD-8

Program DoD-8

DoD-8A

Serologic Diagnosis of Viscerotropic Leishmaniasis (VTL)

DoD-8B

Development of a Leishmania Skin Test Antigen (LSTA)

DoD-9

Identification of the Genetic Factors Which Control Tropism in Leishmania

DoD-10

Pyridostigmine Synergistic Toxicity Study

DoD-11

Male/Female Differential Tolerances to Pyridostigmine Bromide

DoD-12

Forward Deployable Diagnostics for Infectious Diseases

DoD-13

Effects of Persian Gulf War Service on Military Working Dogs

DoD-14

Risk Factors Among US Army Soldiers for Enrolling on the Department of Veterans Affairs Gulf War Registry

DoD-15

Comparative Mortality Among US Military Personnel Worldwide During Operations Desert Shield and Desert Storm

DoD-16

Kuwait Oil Fire Health Risk Assessment

DoD-17

Retrospective Studies Involving Military Use of Pyridostigmine as a Pretreatment for Nerve Agent Poisoning

DoD-18

Kuwait Oil Fires Troop Exposure Assessment Model (TEAM)

DoD-19

Persian Gulf Veterans Health Tracking System

DoD-20

A Statistical Study Correlating the Reported Cases of Gulf War Syndrome to Battlefield Locations of Afflicted US Army Personnel During the Iraq-Kuwait War; Part 1: Method to Related Troop Deployment and the Reported Cases of Gulf War Syndrome and Probable Incidence of Maladies Defined by ICD-9-CM

DoD-21

Study of Variability In Pyridostigmine Inhibition of Blood Cholinesterases in Healthy Adults and Individuals With Symptoms Following Participation in Operation Desert Storm

DoD-22

Chronic Organophosphorous Exposure and Cognition

DoD-23

Acute and Long-Term Impact of Deployment to Southwest Asia on the Physical and Mental Health of Soldiers and their Families

DoD-30

Epidemiological Studies Persian Gulf War Illnesses, PG Women's Health Linkage Study

DoD-31

Dysregulation of the Stress Response in the Persian Gulf Syndrome

DoD-32

Neuropsychological Functioning in Persian Gulf Era Veterans

DoD-33

Effects of Pyridostigmine in Flinders Line Rats Differing in Cholinergic Sensitivity

DoD-34

Characterization of Emissions from Heaters Burning Leaded Diesel Fuel in Unvented Tents

DoD-35

Feasibility of Investigating Whether There is a Relationship Between Birth Defects and Service in the Gulf War.

DoD-36

Fatigue in Persian Gulf Syndrome-Physiologic Mechanisms

DoD-37

Neurobehavioral and Immunological Toxicity of Pyridostigmine, Permethrin, and DEET in Male and Female Rats

DoD-38

Diagnostic Antigens of Leishmania tropica

DoD-39

A Controlled Epidemiological and Clinical Study into the Effect of Gulf War Service on Servicemen and Women of the United Kingdom Armed Forces

DoD-40

Psychological and Neurobiological Consequences of the Gulf War Experience

DoD-41

Evaluation of Muscle Function in Persian Gulf Veterans

DoD-42

The Symptomatic Persian Gulf Veterans Protocol: An Analysis of Risk Factors with an Immunologic and Neuropsychiatric Assessment

DoD-44

Investigation of Seminal Plasma Hypersensitivity Reactions

DoD-45

Physical and Emotional Health of Gulf War Veterans Women

DoD-46

Exploratory Data Analysis with the CCEP Database

DoD-47

Study of Mycoplasmal Infections in Gulf War Veterans

DoD-48

Assessment of Genomic Instability via Chromosome 7 Inversion Frequency in a Gulf-War Syndrome Cohort vs Selected Control Groups

DoD-49

Diagnosis and Dosimetry of Exposure to Sulfur Mustard: Development of Standard Operating Procedures and Exploratory Research on Protein Adducts

DoD-50

Toxicokinetics of 0-Ethyl S-(2-Diisopropylaminoethyl) Methylphosphonothioate [(+)-VX] in Rats, Hairless Guinea Pigs and Marmosets - Identification of Metabolic Pathways

DoD-51

Transgenic Engineering of Cholinesterases: Tools for Exploring Cholinergic Responses

DoD-52

Female Gender and Other Potential Predictors of Functional Health Status Among Persian Gulf War Veterans

DoD-53

Long-Term Effects of Subclinical Exposures to Sarin

DoD-54

Assessment of Subchronic Neurobehavioral and Neuropathologic Effects in Rats

DoD-55

Low-Level Exposure to GB Vapor in Air: Diagnosis/Dosimetry, Lowest Observable Effect Levels, Performance-Incapacitation, and Possible Delayed Effects

DoD-56

Low-Level Sarin Neurotoxicity and Its Modulation by Pyridostigmine

DoD-57

Physiologic Effects of Stress in Gulf War Veterans

DoD-58

Illness Among Persian Gulf War Veterans: Case Validation Studies

DoD-59

Pyridostigmine-induced Neurodegeneration: Role of neuronal Apoptosis

DoD-60

Butyrylcholinesterase Genetic Variants in Persons with Gulf War Illness

DoD-61

Neurophysiologic and Neuropathologic Effects in Monkeys of Low Level Exposures to Sarin, Pyridostigmine, Pesticides, and Botulinum Toxoid

DoD-62

arin and Pyridostigmine Interaction under Physical Stress: Neurotoxic Effects in Mice

DoD-63

PGW Veterans: Epidemiological and Clinical Evidence for Residual Organophosphate Neurotoxicity

DoD-64

Individual Differences in Neurobehavioral Effects of Pyridostigmine

DoD-65

Multi-disciplinary Pathophysiologic Studies of Neurotoxic Gulf War Related Syndromes Leading to Diagnosis and Treatment

DoD-66

Testing for Mycoplasmal Infection Replicability of Nucleoprotein Gene Tracking and Forensic Polymerase Chain Reaction

DoD-67

Antibacterial Treatment Method Based Upon the Excretion of Dead and Decaying Spherical Bacteria

DoD-69

Five Year Follow-Up of Arm Personnel Exposed to Chemical Warfare Agents

DoD-70

War Syndromes from 1900 to the Present: Symptom Patterns and Long-term Health Outcomes

DoD-71

A Comparison of Post Deployment Hospitalization Between Vietnam and Gulf War Veterans

DoD-72

Long-term Effects of Subchronic Exposure to Sarin, Alone and with Stress or Other Chemicals

DoD-73

Post-deployment Morbid Stress, Behavior and Health: Developing a Model for Predicting Morbidity, Mortality, and other Adverse Outcomes

DoD-74

Relationship of Stress Exposures to Health in Gulf War Veterans

DoD-75

Toxic Interactions of Prophylactic Drugs and Pesticides

DoD-76

Evaluations of Immunotoxicity due to Concurrent Exposure to DEET, Pyridostigmine, and JP-8 Jet Fuel

DoD-77

Percutaneous Absorption of Chemical Mixtures Relevant to the Gulf War

DoD-78

Experimental Models of Gulf War Syndrome

DoD-79

Time Course of Stress-induced Impairment of Blood Brain Barrier

DoD-80

Molecular Regulation of Corticosteroid Receptor Expression in Stress-Responsive Cells

DoD-81

Immunotoxicity due to Coexposure to DEET, Pyridostigmine, and Stress

DoD-82

Feasibility of Developing a Registry of PTSD Affected Veteran Sib Pairs

DoD-83

Risk for Stress-related Substance Abuse: the Effects of Family History of Alcoholism

DoD-84

Psychobiologic Alterations in Persian Gulf War Veterans with and without PTSD

DoD-85

CNS Cytokines and CRH in Gulf War Veterans with Multiple Unexplained Symptoms

DoD-86

Effects of Combat Stress on Structure and Function of the Hippocampus

DoD-87

Measurement and Validation of Psychosocial Risk and Resilience Factors Accounting for Physical and Mental Health and Health-Related Quality of Life among PGWVs

DoD-88

Clinical Relevance of novel Immunological Markers in PTSD

DoD-89

Limbic Blood Flow and Opiate Receptor PET in Posttraumatic Stress Disorder

DoD-90

SPECT Benzodiazepine Receptor and MR Imaging in PTSD

DoD-91

Neurological and Circadian Substrates of PTSD-like Behaviors

DoD-92

Traumatic Experiences Persistently Enhance Cue-dependent Learning: Toward an Animal Model of Chronic Stress and Posttraumatic Stress Disorder

DoD-93

Troops Exposed to New Agents at Aberdeen Proving Ground - Follow Up Investigation

Department of Health and Human Services

HHS-1

Health Assessment of Persian Gulf War Veterans from Iowa

HHS-2

Disease Cluster in a Pennsylvania Air National Guard Unit, EPI-AID 95-18

HHS-3

Biomarkers of Susceptibility and Polycyclic Aromatic Hydrocarbon (PAH) Exposure in Urine and blood Cell DNA from U.S. Army Soldiers Exposed to Kuwaiti Oil Well Fires

HHS-4

Suspected Increase of Birth Defects and health Problems Among Children Born to Persian Gulf War Veterans In Mississippi

HHS-5

Cognitive Function and Symptom Patterns in Persian Gulf Veterans

HHS-6

Defining Gulf War Illness

HHS-7

Immunotoxicity of Dermal Permethrinand Cis-Urocanic Acid

HHS-8

Strategy to Identify Non-Additive Response to Chemical Mixtures

Department of Veterans Affairs

VA-1

Mortality Follow-up Study of Persian Gulf Veterans, First Update

VA-2

National Health Survey of Persian Gulf Veterans

VA-2A

VA National Survey of Persian Gulf Veterans - Phase I

VA-2B

VA National Survey of Persian Gulf Veterans - Phase II

VA-2C

VA National Survey of Persian Gulf Veterans - Phase III

VA-3

Use of Roster of Veterans Who Served in Persian Gulf Area

VA-4

Boston Environmental Hazards Research Center Program

VA-4Core

Boston Environmental Hazards Research Center Program

VA-4A

Evaluation of Cognitive Functioning of Persian Gulf Veterans

VA-4B

Evaluation of Neurological Functioning in Persian Gulf Veterans

VA-4C

Gulf War And Vietnam Veterans Cancer Incidence Surveillance

VA-4D

Evaluation of Respiratory Dysfunction Among Gulf War Veterans

VA-4E

The Aromatic Hydrocarbon Receptor (AhR) as a Biomarker of Susceptibility

VA-4F

Validity of Computerized Tests

VA-5

East Orange Environmental Hazards Research Center Program

VA-5Core

East Orange Environmental Hazards Research Center Program

VA-5A

Health and Exposure Survey of Persian Gulf Veterans

VA-5B

Physiological and Psychological Assessments of Persian Gulf Veterans

VA-5C

Effects of Exertion and Chemical Stress on Persian Gulf Veterans

VA-5D

Effects of Genetics and Stress on Responses to Environmental Toxins

VA-6

Portland Environmental Hazards Research Center Program

VA-6Core

Core Program: Portland Environmental Hazards Research Center: Environment, Veterans Health and the Gulf War Syndrome. Core Project for Clinical and Epidemiology Research

VA-6A

Psychosocial, Neuropsychological and Neurobehavioral Assessment (Project I)

VA-6B

Clinical and Neuroendocrine Aspects of Fibromyalgia (Project II)

VA-6C

Neurotoxicity of Environmental Pollutants and Warfare Agents (Project III)

VA-6D

DNA Damage from Chemical Agents and Its Repair (Project IV)

VA-6E

Clinical and Epidemiology Leishmania Research

VA-7

Desert Storm Reunion Survey

VA-8

Psychological Test Data of Gulf War Veterans Over Time

VA-9

Evaluation of Cognitive Functioning in Persian Gulf War Veterans Reporting War-related Health Problems

VA-10

Memory and Attention in PTSD

VA-11

Neuropsychological Functioning in Veterans

VA-12

Psychological Assessment of Operation Desert Storm Returnees

VA-13

Neurobehavioral Aspects of Persian Gulf Experiences: A Pilot Study

VA-15

Vaccine-Mediated Immunity Against Leishmaniasis

VA-16

Protective Immunity in Experimental Visceral Leishmaniasis

VA-17

Immunological Evaluation of Persian Gulf Veterans

VA-18

Chronic Gastrointestinal Illness in Persian Gulf Veterans

VA-20

Psychological Adjustment in Operation Desert Shield/Storm Veterans

VA-21

A Comparison of PTSD Symptomatology among Three Army Medical Units Involved in ODS

VA-36

Stress Symptoms and Their Causal Attribution in Desert Storm Veterans

VA-40

Musculoskeletal Symptoms in Gulf War Syndrome

VA-46

Diarrhea in Persian Gulf Veterans: An Irritable Bowel-Like Disorder

VA-47

Retrospective Verification of Mustard Gas Exposure

VA-48

Cross-Sensitization as a CNS Model for Gulf War Chemical Intolerance

VA-49

Sensitivity to Pyridostigmine Bromide: Persistent Neural Dysfunction

VA-50

Neuropsychological Findings in a Sample of Operation Desert Storm Veterans

VA-51

Psychobiological Assessment of Desert Storm Veterans

VA-53

Spouses and Children Program

VA-54

Follow-up of Psychological and Neurocognitive Gulf War Outcome: Relation to Stress

VA-55

Antibiotic Treatment of Gulf War Veterans' Illnesses

Department of Defense / Veterans Affairs Shared Projects

VA/DoD-1D/1V

A Randomized, Multi-Center, Controlled Trial of Multi-Modal Therapy in Veterans with Gulf War Illnesses

VA/DoD-2DA/2VA

Follow-Up Investigation of Troops Exposed to Nerve Agents at Aberdeen Proving Ground

VA/DoD-2VB/2DB

Patterns of Pre-Persian Gulf War Illness and Health Care Seeking, Pilot Study

VA/DoD-2D/2V

VA/DoD Core Funding of the Medical Follow-up Agency