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Physics

Oh, What a Tangled Web These Particles Weave!

Researchers in the Time and Frequency Division of NIST’s Boulder, Colo., Laboratories have made the first observation of quantum entanglement of four particles. Featured as the cover story in the March 16, 2000, issue of Nature, the experiment is considered an essential step toward the future development of a quantum computer—a device whose computing capabilities would be defined by the laws of quantum physics, far surpassing any conventional computer in power and efficiency when applied to certain problems.

Entanglement is a form of linking between two or more particles in which some of the quantum properties of those particles become “shared.” Subsequently, information about one particle’s properties is instantly and “mysteriously” linked to the others, even when the particles become widely separated. Albert Einstein termed this phenomenon “spooky action-at-a-distance,” and it remains one of the most puzzling features of quantum mechanics.

To achieve the entanglement, NIST researchers confined four singly ionized beryllium atoms in an electromagnetic trap so that they were spaced along a line. They then used lasers to cool the atoms to near absolute zero and forced them all to be in the same spin state (atoms can be in one of two states: spin-up or spin-down). Suitably tuned laser light then entangled the atoms by exploiting their mutual electrical repulsion, creating a superposition of all four atoms being both spin-up and spin-down simultaneously.

Quantum superpositions are often explained in terms of the famous cat postulated in 1935 by physicist Erwin Schroedinger. Schroedinger considered the possibility that a cat could be made to be both dead and alive at the same time when the rules of quantum mechanics are followed to an extreme. “Schroedinger’s cat” soon became a shorthand way to refer to a whole class of superposed quantum states.

Although the NIST result represents the largest entangled superposition ever achieved, four atoms is still far removed from the complexity of a cat. However, as NIST researcher Christopher Monroe explains, “Our technique is scalable to a lot more atoms. If we get to that level, we’ll not only bring the strangest feature of quantum mechanics closer to the macroscopic world, but we also may have a quantum computer.”

Scientists predict that such a computer could store and process superpositions of numbers in parallel, using the extra linkage afforded by entanglement. A quantum computer would quickly solve problems such as the factoring of extremely large numbers and the handling of huge arrays of data—tasks requiring so much memory that conventional computers cannot handle them.

For technical information, contact Christopher Monroe at (303) 497-7415, monroe@boulder.nist.gov.

Media Contact:
Collier Smith (Boulder), (303) 497-3198

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Manufacturing

MEP Helps Small Firms Get Leaner, Cleaner and More Productive

Smaller manufacturers now will have access to “lean manufacturing” training previously available only to large companies, thanks to a recently formed partnership between The Modernization Forum, the association for America’s manufacturing extension community, and Productivity Inc.

Originating in Japan in the 1970s, lean manufacturing is a concept that eliminates manufacturing activities or actions that add no real value to the product or service. Under the agreement, field manufacturing specialists at NIST Manufacturing Extension Partnership centers around the country will receive training in Productivity’s “5-S Visual Systems,” a lean manufacturing course previously available only to large manufacturers.

The course teaches how to map a current situation at a manufacturing plant, create an optimal condition and keep it that way. The training also teaches workers how to organize their workplace for increased efficiency, safety and cleanliness. These techniques have become standard practices in large manufacturing plants but are used by very few smaller manufacturers.

For assistance with lean manufacturing techniques, as well as other business and technical projects, small manufacturers can call (800) MEP-4MFG (637-4634) or go to NIST MEP’s World Wide Web site, www.mep.nist.gov, to reach the NIST MEP center serving their region.

Media Contact:
Jan Kosko, (301) 975-2767Up

 

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ATP

Carbon-Copy Pigs Are Latest Milestone in Organ Transplant Research

PPL Therapeutics Inc., of Blacksburg, Va., announced on March 14, 2000, that it had achieved the world’s first successful cloning of pigs from adult cells. Pigs are a particularly difficult species to clone because cloning is a very inefficient process and a sow must have a minimum number of viable fetuses to carry any to term. The five piglets born on March 5, 2000, say PPL researchers, mark an important milestone in the development of genetically engineered pigs to supply tissues and organs for transplant into humans. Because they share with humans relatively similar physiologies, pigs are considered a potentially valuable source of transplant organs—hearts and kidneys, for example—that are in critically short supply.

One of the main technical barriers to such “xenotransplants” is the “hyperacute rejection” reaction from the human immune system, which recognizes a particular sugar complex on the surface of pig cells as foreign. One particular pig gene is responsible for this tell-tale sugar, and researchers hope that organs from a genetically engineered pig lacking this gene could be transplanted without triggering the host’s immune system. A U.S. subsidiary of London-based PPL Therapeutics Plc, PPL received a 1999 award from the NIST Advanced Technology Program to develop the technology to clone “knock-out” pigs—swine with that specific gene inactivated. In addition, more genes will have to be introduced into pig cells to prevent more delayed rejection responses.

The use of pig organs would offer tremendous health, economic and social benefits by providing sufficient organs to meet demand, reducing the tens of billions of dollars now spent annually caring for patients with organ failure, and improving their quality of life. In their ATP application, PPL pro- jected a market for animal transplants of nearly $6.5 billion within 10 years of launch. In addition, the new technology will create new industries and enable advances in other fields, such as treatment of vascular disease, the science of embryology, the development of animal models for human diseases and livestock improvement.

The PPL news release is available on the web at www.ppl-therapeutics.com/Welcome/News/news.cfm. More information on the Advanced Technology Program, along with a description of the PPL project, may be found at www.atp.nist.gov.

Media Contacts:

Michael Baum, (301) 975-2763

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Cryogenics

NIST Helps Develop Some of World’s Coldest Refrigerators

For most people, refrigeration means a large box where milk is kept cool and ice cream is kept frozen. But there are some people for whom refrigeration means cooling things down to just a few degrees above absolute zero. Now, that’s really cold! NIST has been a pioneer in the development of these extremely low temperature refrigerators, called cryocoolers.

Since 1950, about 100,000 cryocoolers have been manufactured in the United States for military applications such as cooling infrared sensors in tanks, airplanes and missiles. However, the past decade saw the market for cryocoolers move to the civilian side—a trend that appears to be growing strong. For example, cryopumps for the semiconductor fabrication industry have been the primary application of the technology since 1990, with the devices being produced at a rate of about 20,000 per year. And as semiconductor components continue to shrink, companies will need cryocoolers with less vibration and that can reach temperatures as low as 10 to 15 Kelvin above absolute zero. At the other end of the scale, large cryocoolers are being developed for liquefying natural gas and methane-rich gas emitted from large landfills. Perhaps the application most familiar to the public is the use of cryocoolers in superconducting magnets for magnetic resonance imaging systems where temperatures can get down to 4 Kelvin above absolute zero.

A new paper from NIST reviews the history and development of cryocoolers, focusing on one type called a pulse-tube refrigerator. Because these refrigerators have no moving parts at the cold end, they provide less vibration, higher reliability and lower cost. They also have a longer lifespan—from three to 10 years—and are desirable for applications in outer space. Other potential uses for pulse-tube refrigerators include industrial gas liquefaction and power applications of superconductors.

For a copy of the paper, “Development of the Pulse Tube Refrigerator as an Efficient and Reliable Cryocooler” (no. 11-00), contact Sarabeth Harris, MC104, NIST, Boulder, Colo. 80303-3337; (303) 497-3237; sarabeth@boulder.nist.gov.

Media Contact:
Fred McGehan (Boulder), (303) 497-3246

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Administration

Kayser, Mehuron to Head Tech Services, Information Tech Units

Richard F. Kayser and William O. Mehuron have been named directors of NIST’s Technology Services Unit and Information Technology Laboratory, respectively. Both men have been acting directors of their organizational units since last year; Kayser since August and Mehuron since April.

As head of Technology Services, Kayser leads the unit whose components include the Standard Reference Materials Program, Standard Reference Data Program, the Office of Weights and Measures, the National Voluntary Laboratory Accreditation Program, the NIST Calibration Program, the Office of Technology Partnerships, NIST’s Small Business Innovation Research Program and the Metric Program. He started at NIST’s predecessor, the National Bureau of Standards, in 1976 as a National Science Foundation Fellow and joined the Thermophysics Division as a staff member the following year. He became the division’s chief in 1989 and chief of the Physical and Chemical Properties Division in 1996.

Mehuron joined NIST in 1999 to direct the information technology portion of the Advanced Technology Program. Previously, he had served since 1995 as director of the Systems Acquisition Office (and as acting deputy undersecretary from 1997-1998) for the National Oceanic and Atmospheric Administration. Earlier in his career, Mehuron was deputy director for research and engineering at the National Security Agency and held senior management positions with several private-sector technology organizations. As ITL director, he is responsible for the laboratory whose programs for industry include high performance computing and communications systems; emerging network technologies; access to, exchange, and retrieval of complex information; computational and statistical methods; information security; and testing tools and methods to improve the quality of software.

Media Contact:
Michael Newman, (301) 975-3025

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Editor: Michael Newman
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Last updated:
March 28, 2000
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