In the U.S.—

In Canada—

• Antimydriatic

Dapiprazole ( da-PI-pray-zole) is used in the eye to reduce the size of the pupil after certain kinds of eye examinations.

Some eye examinations are best done when your pupil (the black center of the colored part of your eye) is very large, so the doctor can see into your eye better. This medicine helps to reduce the size of your pupil back to its normal size after the eye examination.

Dapiprazole is available in the following dosage form:

Ophthalmic
• Ophthalmic solution (eye drops) (U.S. and Canada)

In deciding to use a medicine, the risks of using the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For dapiprazole, the following should be considered:

Allergies—Tell your doctor if you have ever had any unusual or allergic reaction to dapiprazole. Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes.

Pregnancy—Dapiprazole has not been studied in pregnant women. However, dapiprazole has not been shown to cause birth defects or other problems in animal studies.

Breast-feeding—It is not known whether dapiprazole passes into the breast milk. However, this medicine has not been reported to cause problems in nursing babies.

Children—Studies on this medicine have been done only in adult patients, and there is no specific information comparing use of dapiprazole in children with use in other age groups.

Older adults—Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults. Although there is no specific information comparing use of dapiprazole in the elderly with use in other age groups, this medicine is not expected to cause different side effects or problems in older people than it does in younger adults.

Other medicines—Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your health care professional if you are using any other ophthalmic (eye) prescription or nonprescription (over-the-counter [OTC]) medicine.

• Eye problems, other—Use of dapiprazole may make the condition worse

Dosing—

The dose of dapiprazole will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of dapiprazole. If your dose is different. do not change it unless your doctor tells you to do so.

• For ophthalmic solution (eye drops) dosage form:
  • For reduction of size of pupil of eye:
    • Adults—One drop, then one drop in five minutes, following eye examination.
    • Children—Use and dose must be determined by your doctor.

Even after using this medicine, you may have blurred vision or other vision problems. If any of these occur, do not drive, use machines, or do anything else that could be dangerous if you are not able to see well.

This medicine may cause your eyes to become more sensitive to light than they are normally. Wearing sunglasses and avoiding too much exposure to bright light may help lessen the discomfort.

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

• Less common
  • Irritation (severe) or swelling of the clear part of the eye  
  
  

Other side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. However, check with your doctor if any of the following side effects continue or are bothersome:

• More common
  • Burning of eye when medicine is applied;  redness of the white part of the eye 
  
  

• Less common
  • Blurring of vision;  browache;  drooping of upper eyelid;  dryness of eye;  headache;  increased sensitivity of eye to light;  itching of eye;  redness of eyelid;  swelling of eyelid ;  swelling of the membrane covering the white part of the eye;  tearing of eye 
  
  

Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor.