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Erythromycin and Sulfisoxazole

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(er ith roe mye' sin) (sul fi sox' a zole)

Brand name(s): Eryzole; Pediazole

Contents of this page:

Why is this medication prescribed?

The combination of erythromycin and sulfisoxazole (a sulfa drug) is used to treat certain ear infections caused by bacteria. It usually is used in children.

This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

How should this medicine be used?

Erythromycin and sulfisoxazole comes as a liquid to take by mouth. It usually is taken every 6 hours (four times a day) for 10 days. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take erythromycin and sulfisoxazole exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Shake the liquid well before each use to mix the medication evenly.

Drink a full glass of water after each dose.

Continue to take erythromycin and sulfisoxazole even if you feel well. Do not stop taking erythromycin and sulfisoxazole without talking to your doctor.

What special precautions should I follow?

Before taking erythromycin and sulfisoxazole,

What special dietary instructions should I follow?

Do not take this medication with, or just after, fruit juices, carbonated drinks, or tea. It can be taken with or between meals.

What should I do if I forget a dose?

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

What side effects can this medication cause?

Although side effects from erythromycin and sulfisoxazole are not common, they can occur. Tell your doctor if any of these symptoms are severe or do not go away:

If you experience any of the following symptoms, call your doctor immediately:

What storage conditions are needed for this medicine?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Keep it in the refrigerator, and throw away any unused medication after 14 days. Do not freeze. Talk to your pharmacist about the proper disposal of your medication.

In case of emergency/overdose

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

What other information should I know?

Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your response to erythromycin and sulfisoxazole.

Do not let anyone else take your medication. Your prescription is probably not refillable. If you still have symptoms of infection after you finish the erythromycin and sulfisoxazole, call your doctor.

Last Revised - 01/01/2003


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The MedMaster™ Patient Drug Information database provides information copyrighted by the American Society of Health-System Pharmacists, Inc., Bethesda, Maryland Copyright© 2004. All Rights Reserved.