Other drug names:	A-Am  An-Az  B  C-Ch  Ci-Cz  D-Dh  Di-Dz  E  F  G  H  I-J  K-L  M-Mh  Mi-Mz  N-Nh  Ni-Nz  O  P-Pl  Pm-Pz  Q-R  S-Sn  So-Sz  T-To  Tp-Tz  U-V  W-Z  0-9

Other commonly used names are vitamin H; coenzyme R; vitamin Bw.

• Nutritional supplement, vitamin

Biotin ( BYE-oh-tin) supplements are used to prevent or treat biotin deficiency.

Vitamins (VYE-ta-mins) are compounds that you must have for growth and health. They are needed in only small amounts and are usually available in the foods that you eat. Biotin is necessary for formation of fatty acids and glucose, which are used as fuels by the body. It is also important for the metabolism of amino acids and carbohydrates.

A lack of biotin is rare. However, if it occurs it may lead to skin rash, loss of hair, high blood levels of cholesterol, and heart problems.

Some conditions may increase your need for biotin. These include:

• Genetic disorder of biotin deficiency
• Seborrheic dermatitis in infants
• Surgical removal of the stomach

Increased need for biotin should be determined by your health care professional.

Claims that biotin supplements are effective in the treatment of acne, eczema (a type of skin disorder), or hair loss have not been proven.

Biotin supplements are available without a prescription in the following dosage forms:

Oral
• Capsules (U.S.)
• Tablets (U.S. and Canada)

For good health, it is important that you eat a balanced and varied diet. Follow carefully any diet program your health care professional may recommend. For your specific vitamin and/or mineral needs, ask your health care professional for a list of appropriate foods. If you think that you are not getting enough vitamins and/or minerals in your diet, you may choose to take a dietary supplement.Biotin is found in various foods, including liver, cauliflower, salmon, carrots, bananas, soy flour, cereals, and yeast. Biotin content of food is reduced by cooking and preserving.

Vitamins alone will not take the place of a good diet and will not provide energy. Your body needs other substances found in food, such as protein, minerals, carbohydrates, and fat. Vitamins themselves cannot work without the presence of other foods.

The daily amount of biotin needed is defined in several different ways.

For U.S.—
• Recommended Dietary Allowances (RDAs) are the amount of vitamins and minerals needed to provide for adequate nutrition in most healthy persons. RDAs for a given nutrient may vary depending on a person's age, sex, and physical condition (e.g., pregnancy).
• Daily Values (DVs) are used on food and dietary supplement labels to indicate the percent of the recommended daily amount of each nutrient that a serving provides. DVs replace the previous designation of United States Recommended Daily Allowances (USRDAs).

For Canada—
• Recommended Nutrient Intakes (RNIs) are used to determine the amounts of vitamins, minerals, and protein needed to provide adequate nutrition and lessen the risk of chronic disease.

Because lack of biotin is rare, there is no RDA or RNI for it. Normal daily recommended intakes for biotin are generally defined as follows:

• Infants and children—
  • Birth to 3 years of age: 10 to 20 micrograms (mcg).
  • 4 to 6 years of age: 25 mcg.
  • 7 to 10 years of age: 30 mcg.
• Adolescents and adults—
  • 30 to 100 mcg.

If you are taking this dietary supplement without a prescription, carefully read and follow any precautions on the label. For biotin, the following should be considered:

Allergies—Tell your health care professional if you have ever had any unusual or allergic reaction to biotin. Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes.

Pregnancy—It is especially important that you are receiving enough vitamins and minerals when you become pregnant and that you continue to receive the right amount of vitamins and minerals throughout your pregnancy. The healthy growth and development of the fetus depend on a steady supply of nutrients from the mother. However, taking large amounts of a dietary supplement in pregnancy may be harmful to the mother and/or fetus and should be avoided.

Breast-feeding—It is especially important that you receive the right amounts of vitamins so that your baby will also get the vitamins needed to grow properly. However, taking large amounts of a dietary supplement while breast-feeding may be harmful to the mother and/or baby and should be avoided.

Children—Problems in children have not been reported with intake of normal daily recommended amounts.

Older adults—Problems in older adults have not been reported with intake of normal daily recommended amounts.

Dosing—

The amount of biotin to meet normal daily recommended intakes will be different for different individuals. The following information includes only the average amounts of biotin.

• For oral dosage form (capsules or tablets):
  • To prevent deficiency, the amount taken by mouth is based on normal daily recommended intakes:
    • Adults and teenagers—30 to 100 micrograms (mcg) per day.
    • Children 7 to 10 years of age—30 mcg per day.
    • Children 4 to 6 years of age—25 mcg per day.
    • Children birth to 3 years of age—10 to 20 mcg per day.
  • To treat deficiency:
    • Adults, teenagers, and children—Treatment dose is determined by prescriber for each individual based on severity of deficiency.

Missed dose—

If you miss taking biotin supplements for one or more days there is no cause for concern, since it takes some time for your body to become seriously low in biotin. However, if your health care professional has recommended that you take biotin, try to remember to take it as directed every day.

Storage—

To store this dietary supplement:

• Keep out of the reach of children.
• Store away from heat and direct light.
• Do not store in the bathroom, near the kitchen sink, or in other damp places. Heat or moisture may cause the dietary supplement to break down.
• Keep the dietary supplement from freezing. Do not refrigerate.
• Do not keep outdated dietary supplements or those no longer needed. Be sure that any discarded dietary supplement is out of the reach of children.

Side Effects of This Dietary Supplement

No side effects have been reported for biotin in amounts up to 10 milligrams a day. However, check with your health care professional if you notice any unusual effects while you are taking it.

Revised: 04/25/1995