Skip navigation
MedlinePlus Trusted Health Information for You U.S. National Library of MedicineNational Institutes of Health
Contact Us FAQs Site Map About MedlinePlus
español Home Health Topics Drug Information Medical Encyclopedia Dictionary News Directories Other Resources

Other drug names:  A-Am  An-Az  B  C-Ch  Ci-Cz  D-Dh  Di-Dz  E  F  G  H  I-J  K-L  M-Mh  Mi-Mz  N-Nh  Ni-Nz  O  P-Pl  Pm-Pz  Q-R  S-Sn  So-Sz  T-To  Tp-Tz  U-V  W-Z  0-9

Orphenadrine  (Systemic)

Printer-friendly versionE-mail this page to a friend
Contents of this page:

Brand Names

In the U.S.—

  • Antiflex
  • Banflex
  • Flexoject
  • Mio-Rel
  • Myolin
  • Myotrol
  • Norflex
  • Orfro
  • Orphenate

In Canada—

  • Disipal
  • Norflex

Category


Description

Orphenadrine ( or-FEN-a-dreen) is used to help relax certain muscles in your body and relieve the stiffness, pain, and discomfort caused by strains, sprains, or other injury to your muscles. One form of orphenadrine is also used to relieve trembling caused by Parkinson's disease. However, this medicine does not take the place of rest, exercise or physical therapy, or other treatment that your doctor may recommend for your medical problem.

Orphenadrine acts in the central nervous system (CNS) to produce its muscle relaxant effects. Orphenadrine also has other actions (anticholinergic) that produce its helpful effects in Parkinson's disease. Orphenadrine's CNS and anticholinergic actions may also be responsible for some of its side effects.

In the U.S., this medicine is available only with your doctor's prescription. In Canada, it may be available without a prescription. It is available in the following dosage forms:



Before Using This Medicine

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For orphenadrine, the following should be considered:

Allergies—Tell your doctor if you have ever had any unusual or allergic reaction to orphenadrine. Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes.

Pregnancy—Orphenadrine has not been reported to cause birth defects or other problems in humans.

Breast-feeding—It is not known whether orphenadrine passes into the breast milk. However, orphenadrine has not been reported to cause problems in nursing babies.

Children—Studies on this medicine have been done only in adult patients, and there is no specific information comparing use of orphenadrine in children with use in other age groups.

Older adults—Many medicines have not been tested in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information about the use of orphenadrine in the elderly.

Other medicines—Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking orphenadrine, it is especially important that your health care professional knows if you are taking any of the following:

Other medical problems—The presence of other medical problems may affect the use of orphenadrine. Make sure you tell your doctor if you have any other medical problems, especially:


Proper Use of This Medicine

Dosing—

The dose of orphenadrine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of orphenadrine. If your dose is different, do not change it unless your doctor tells you to do so.

Missed dose—

If you miss a dose of this medicine and remember within an hour or so of the missed dose, take it right away. But if you do not remember until later, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage—

To store this medicine:


Precautions While Using This Medicine

If you will be taking this medicine for a long time (for example, more than a few weeks), your doctor should check your progress at regular visits.

This medicine may add to the effects of alcohol and other CNS depressants (medicines that slow down the nervous system, possibly causing drowsiness). Some examples of CNS depressants are antihistamines or medicine for hay fever, other allergies, or colds; sedatives, tranquilizers, or sleeping medicine; prescription pain medicine or narcotics; barbiturates; medicine for seizures; other muscle relaxants; or anesthetics, including some dental anesthetics. Do not drink alcoholic beverages, and check with your doctor before taking any of the medicines listed above, while you are using this medicine.

This medicine may cause some people to have blurred vision or to become drowsy, dizzy, lightheaded, faint, or less alert than they are normally. It may also cause muscle weakness in some people. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are dizzy or are not alert and able to see well.

Orphenadrine may cause dryness of the mouth. For temporary relief, use sugarless candy or gum, melt bits of ice in your mouth, or use a saliva substitute. However, if dry mouth continues for more than 2 weeks, check with your dentist. Continuing dryness of the mouth may increase the chance of dental disease, including tooth decay, gum disease, and fungus infections.


Side Effects of This Medicine

Side Effects of This Medicine

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

Other side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. However, check with your doctor if any of the following side effects continue or are bothersome:

Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor.



Revised: 08/11/1995

Micromedex, Inc. Disclaimer

Copyright© 2003 Thomson MICROMEDEX. All rights reserved. USP DI® and Advice for the Patient® are registered trademarks of USP used under license to Micromedex, a business of Thomson Healthcare Inc. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.