On March 2, 2004, NIH announced that it had stopped the estrogen-alone study in the interest of safety after careful consideration of preliminary data and an average follow-up of nearly 7 years.

Selected Findings

Dementia and Cognitive Function--Women's Health Initiative Memory Study (June 2004)

• Summary of Results
  
  
• Press Release: Estrogen-Alone Hormone Therapy Could Increase Risk of Dementia in Older Women, June 22, 2004
  
  
• Women's Health Initiative Memory Study Web site
  
  
• Conjugated Equine Estrogens and Incidence of Probable Dementia and Mild Cognitive Impairment in Postmenopausal Women, Women's Health Initiative Memory Study, JAMA, June 23/30, 2004
  
  
• Conjugated Equine Estrogens and Global Cognitive Function in Postmenopausal Women, Women's Health Initiative Memory Study, JAMA, June 23/30, 2004
  
  
• Estrogen and Dementia Insights from the Women's Health Initiative Memory Study (Editorial), JAMA, June 23/30, 2004

Effects of Estrogen-Alone Study: Initial Results (April 2004)

• NHLBI Press Release: WHI Study Finds No Heart Disease Benefit, Increased Stroke Risk with Estrogen Alone, April 13, 2004
  
  
• Questions and Answers About the Estrogen-Alone Study
  
  
• Effects of conjugated equine estrogen in postmenopausal women with hysterectomy, JAMA, April 14, 2004
  
  
• The WHI Estrogen-Alone Trial--Do Things Look Any Better? (Editorial), JAMA, April 14, 2004

NIH Stops Estrogen-Alone Study (March 2004)

• NHLBI Statement, March 2, 2004: NIH Asks Participants in Women's Health Initiative Estrogen-Alone Study to Stop Study Pills, Begin Follow-up Phase
  
  
• Sample letter to Estrogen-Alone Participants
  
  
• NHLBI Advisory for Physicians on the WHI trial of Conjugated Equine Estrogens versus Placebo