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Alternative names Return to top
Icterus intermittens juvenilis; Low-grade chronic hyperbilirubinemia; Familial non-hemolytic-non-obstructive jaundice; Constitutional liver dysfunction; Unconjugated benign bilirubinemiaDefinition Return to top
Gilbert's disease is a multifactorial inherited disorder that affects the way bilirubin is processed by the liver and causes jaundice.Causes, incidence, and risk factors Return to top
Gilbert's disease is common, affecting up to 10% of some Caucasian populations. The most significant symptom of this condition is jaundice. Affected individuals ordinarily have no jaundice. However, jaundice appears under conditions of exertion, stress, fasting, and infections. The condition is usually benign.Symptoms Return to top
Signs and tests Return to top
A serial serum indirect bilirubin shows changes consistent with Gilbert's disease.Treatment Return to top
Usually no treatment is necessary. The focus should be on the underlying condition that caused the jaundice.Expectations (prognosis) Return to top
Jaundice may fluctuate and persist throughout the patients life but usually causes no health problems.Complications Return to top
There are usually no complications.Calling your health care provider Return to top
Call your health care provider if you have jaundice or persistent abdominal pain.Prevention Return to top
Because this is an inherited disorder, there is no proven prevention. Update Date: 10/9/2003 Updated by: Christian Stone, M. D., Division of Gastroenterology, Washington University in St. Louis School of Medicine, St. Louis, MO. Review provided by VeriMed Healthcare Network.
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Page last updated: 28 October 2004 |