Project Number: 6408-21410-005-00
Project Type: Appropriated

Start Date: Oct 01, 2003
End Date: Aug 31, 2006

Objective:
The overall goal of this project is to discover, develop and foster commercialization of new bioactive natural products as new pharmaceuticals or agrichemicals, and to identify, characterize, and develop plants for production of pharmaceuticals or pesticides as potential alternative crops.

Approach:
The approach includes a program of: (1)Development of strategies for rational collection of terrestrial, aquatic, and marine plants, as well as microbes, as a source of novel bioactive natural products; (2)Discovery and development of novel pharmaceutically or agriculturally useful natural products from higher plants; (3)Identification and investigation of new mechanistic targets that may be used in the discovery of pesticides and anti-infective agents; (4)Development of methods and technologies to authenticate, pharmacologically characterize, and chemically analyze higher plants as sources of pharmaceuticals or botanical supplements, and, (5)Investigations of selections, cloning, propagation, agronomics, cultivation, harvesting, and processing of medicinal plants in relation to the chemicstry of desired pharmaceutically or agriculturally useful natural products.

Project Team

Duke, Stephen

Related National Programs

Plant Biological and Molecular Processes (302)

Related Projects

DEVELOPMENT OF NATURAL PRODUCTS FROM PLANTS AND MICROBES FOR REPLACEMENT OF SYNTHETIC PESTICIDES