Your doctor has ordered the drug leuprolide to help treat your illness. The drug can be injected into a muscle or under the skin once a month or every 3 months. It also can be injected daily under the skin. The long-acting form of leuprolide (given once a month or every 3 months) is slowly released into the bloodstream during that period.
This medication is used to treat:
prostate cancer in men
endometriosis in women
early onset of puberty in children
uterine fibroids in women
This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.
Leuprolide is in a class of drugs known as gonadotropin-releasing (LH-RH) hormone analogs. It stops the production of testosterone in men and estrogen in females. Blocking the production of these hormones is desirable because they stimulate the growth of the diseased cells involved in prostate cancer and endometriosis. When the medication is stopped, these hormone levels return to normal.
Precautions
Before taking leuprolide,
tell your doctor and pharmacist if you are allergic to leuprolide or any other drugs.
tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially aspirin and vitamins.
tell your doctor if you have or have ever had abnormal vaginal bleeding or liver disease.
you should know that leuprolide may interfere with the normal menstrual cycle (period) in women and may stop sperm production in men. Amenorrhea (stopping of the monthly menstrual cycle) and vaginal discharge or bleeding may occur with leuprolide therapy. This effect occurs in women who receive 10 weeks or more of therapy and have not been through menopause. However, you should not assume that you cannot get pregnant or that you cannot get someone else pregnant. Women who are pregnant or breast-feeding should tell their doctors before they begin taking this drug. You should not plan to have children while receiving hormone therapy or for a while after treatments. (Talk to your doctor for further details.) Use a reliable method of birth control to prevent pregnancy. Leuprolide may harm the fetus.
Side effects
Although side effects from leuprolide are not common, they can occur. Tell your doctor if any of these symptoms are severe or do not go away:
hot flashes or sudden sweating
night sweats
blurred vision
nausea
breast tenderness
decrease in sexual desire or ability
decrease in appetite
itching, swelling, and redness at injection site
numbness or tingling of the feet or lower legs
constipation
anxiety
unstable mood
If you experience any of the following symptoms, call your doctor immediately:
vomiting
rapid heartbeat
chest pain
breathing difficulties
fever
chills
painful urination
testicular or prostate pain
pain in the legs or groin
Storage conditions
Keep leuprolide in the container it came in and out of reach of children. Store it at room temperature and away from direct sunlight, excess heat and moisture (not in the bathroom). Do not allow leuprolide to freeze. Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.
In case of emergency/overdose
In case of overdose, call your local poison control
center at 1-800-222-1222. If the victim has collapsed
or is not breathing, call local emergency services at
911.
Special instructions
In men, leuprolide may cause increased bone pain and increased difficulty in urinating during the first few weeks of treatment. These effects may result from an initial increase in testosterone. Notify your doctor should this occur.
Continue to take leuprolide even if you feel well. Do not stop taking leuprolide without talking to your doctor.