TABLE OF CONTENTS
Descriptive Summary
Biographical Note
Collection Summary
Index Terms
Administrative Information
Restrictions
Other Descriptive Information
Series Descriptions
Personal and Biographical Series, 1939-1996
Correspondence, 1965-1999
Laboratory Notes and Notebooks, 1959-1985
Reprints and Research Publications, 1950-1993
Photographs and Slides, 1939-1994
Audiovisual, 1948-1990
Oversize Materials
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Archives and Modern Manuscripts Program, History of Medicine Division
Processed by: Aaron D. Purcell, David Serlin, Christie Mawhinney, and Meghan Attalla
Date completed: 1999; Updated 2004
Encoded by: Dan Jenkins; Meghan Attalla
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Collection Number: |
MS C 496 |
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Creator |
Anfinsen, Christian |
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Title |
Christian Anfinsen Papers |
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Dates: |
1939-1999 (bulk 1964-1999) |
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Quantity: |
16 linear feet, 3 oversize boxes |
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Abstract: |
Christian Boehmer Anfinsen, Jr. (1916-1995), was an American biochemist who shared the 1972 Nobel Prize for work that helped explain the structure and composition of proteins in living cells. The collection consists primarily of materials related to Anfinsen's scientific career and is geared toward Anfinsen's research activities both inside and outside of the laboratory. |
Christian Boehmer Anfinsen, Jr., was born 26 March 1916 in Monessen, Pennsylvania, a small town south of Pittsburgh. His father, Christian Boehmer Anfinsen, were Norwegian immigrants who taught their children the Norwegian language and heritage. After living for several years in the Pennsylvania town of Charleroi, the family moved to Philadelphia in the 1920s. In 1933, Anfinsen was admitted to Swarthmore College on a scholarship, where he studied chemistry and played football while working as a waiter in the dining hall. The 1937 edition of the Halcyon, the Swarthmore yearbook, described him this way: "With nostrils distended (denoting passion) [Anfinsen] strolls around campus under a mop of flaxen hair looking soulfully at the co-eds with big blue eyes." Reminiscing about his college years in 1964, Anfinsen noted humbly that "Everyone at Swarthmore was a genius except me."
After receiving his B.S. degree in chemistry in 1937, Anfinsen pursued graduate study at the University of Pennsylvania, where he worked toward a M.S. degree in organic chemistry in 1939 while serving as an assistant instructor. In 1939, the American Scandinavian Foundation awarded Anfinsen a fellowship to develop new methods for analyzing the chemical structure of complex proteins, namely enzymes, at the Carlsberg Laboratory in Copenhagen, Denmark. The dangerous environment created in Europe after the outbreak of World War Two, however, made it necessary for him to return to the United States in 1940. Alan Schechter, one of Anfinsen's postdoctoral students and later an NIH colleague, observed that Anfinsen "had the chance to see and understand the horrors then gripping Europe. His unusually deep and active sense of social responsibility certainly dated from that period, if not earlier."
In 1941, Anfinsen was offered a university fellowship for doctoral study in the Department of Biological Chemistry at Harvard Medical School. In November of that year, he married his first wife, Florence Bernice Kenenger, with whom he had three children. Anfinsen received his Ph.D. in biochemistry in 1943 after completing his dissertation, "Quantitative Histochemical Studies of the Retina," which also served as the basis of his first article [KKBBJM]. Anfinsen taught courses in biological chemistry at Harvard until 1950.
In 1950, the National Heart Institute, one part of the rapidly expanding National Institutes of Health in Bethesda, Maryland, recruited Anfinsen as chief of its Laboratory of Cellular Phsyiology. In 1954, a Rockefeller Foundation fellowship enabled Anfinsen to return to the Carlsberg Laboratory in Copenhagen for a year with Kaj Linderstrom-Lang, and a Guggenheim Foundation fellowship allowed him to study at the Weizmann Institute of Science in Rehovot, Israel, in 1958-1959.
In 1962, Anfinsen returned to Harvard Medical School as a visiting professor, and was promptly invited to become chair of the Department of Biological Chemistry. The NIH, however, wooed Anfinsen back to Bethesda. He was appointed Chief of the brand-new Laboratory of Chemical Biology at the National Arthritis Institute (now the National Institute of Arthritis and Musculoskeletal and Skin diseases), where he remained until 1981. In 1972, Anfinsen was awarded the Nobel Prize in Chemistry on the basis of groundbreaking work in protein chemistry that he had conducted since the early 1950s. He shared the prize with Stanford Moore and William H. Stein, both at Rockefeller University.
In 1978, Anfinsen and his wife were divorced. The following year, he married Libby Esther Shulman Ely and converted to Orthodox Judaism, a commitment he retained for the rest of his life. "Although my feelings about religion still very strongly reflect a fifty-year period of orthodox agnosticism," Anfinsen wrote in 1985, "I must say that I do find the history, practice and intensity of Judaism an extremely interesting philosophical package." In 1981, Anfinsen was offered the position of chief scientist of Tatlit, a scientific research company formed by Yeda, the corporate arm of the Weizmann Institute, and the U.S. Investment firm E.F. Hutton. Two weeks after the Anfinsens arrived in Israel, however, E.F. Hutton withdrew its funding from the project, leaving the couple in limbo. Anfinsen "stuck out the forced inactivity for about a year," as he observed a few years later, "but finally, needing some kind of active scientific base, wrote to friends at the Johns Hopkins University." In 1982, the university offered him a senior position as Professor of Biology and Assistant to the President for Industrial Liaison. From 1983 until 1995, Anfinsen's primary research concerned the study of "hypothermophilic bacteria," microorganisms that thrive at extremely high temperatures.
Throughout his distinguished career Anfinsen received numerous professional honors, including memberships in the American Philosophical Society, the Royal Danish Academy, and the Vatican's Pontifical Academy of Science. From 1962, he served on the Weizmann Institute's board of governors. He was an editor of the journal Advances in Protein Chemistry and Proceedings of the National Academy of Sciences. He also focused considerable energies on a wide range of social and political issues including nuclear disarmament, environmental depredation, and human rights abuses committed against scientists in foreign nations. Aside from his many professional and scientific responsibilities, Anfinsen played viola and piano for relaxation. He was also an avid sailor and took regular excursions on his boat around the Chesapeake Bay and along the eastern seaboard from Boston to Miami. On 14 May 1995, Anfinsen suffered a heart attack and died at Northwest Hospital Center in Randallstown, Maryland, less than a year before his 80th birthday.
Brief Chronology
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1916 |
Born Christian Boehmer Anfinsen, Jr. in Monessen, Pennsylvania (March 26) |
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1937 |
Receives B.S., Swarthmore College |
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1939 |
Receives M.S. (organic chemistry), University of Pennsylvania |
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1939-40 |
Carlsberg Laboratory (Copenhagen), position as Fellow of the American Scandinavian Foundation |
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1941 |
Marries Florence Bernice Keneger; marriage ends, 1978 |
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1943 |
Receives Ph.D. (biochemistry), Harvard Medical School |
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1943-50 |
Assistant professor, Department of Biological Chemistry, Harvard Medical School |
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1944-46 |
Civilian research position at Harvard for the Office of Scientific Research and Development |
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1947-48 |
Senior Fellow, sponsored by the American Cancer Society, at the Medical Nobel Institutte (Stockholm) |
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1950-52 |
Chief, Laboratory of Cellular Physiology, National Heart Institute (NHI), National Institutes of Health [NIH] |
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1952-62 |
Chief, Laboratory of Cellular Physiology and Metabolism, NHI |
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1954 |
Rockefeller Fellow, Carlsberg Laboratory (Copenhagen) |
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1954-62 |
Develops "thermodynamic principle" to describe protein folding in enzymes |
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1958-59 |
Guggenheim Fellow, Weizmann Institute of Science (Rehovot, Israel) |
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1959 |
The Molecular Basis of Evolution published |
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1962-63 |
Visiting Professor, Harvard Medical School, Department of Biological Chemistry |
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1963-81 |
Chief, Laboratory of Chemical Biology, National Institute of Arthritis and Metabolic Diseases [NIAMD, then NIAMDD, later NIDDK] |
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1966-68 |
Uses affinity chromatography techniques to identify amino acid sequence in enzymes |
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1972 |
Shares Nobel Prize in Chemistry with Stanford Moore and William H. Stein |
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1973 |
Begins work on interferon |
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1979 |
Marries Libby Esther Shulman Ely |
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1981 |
Retires from NIH |
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1981-82 |
Weizmann Institute of Science, Visiting Professor of Biochemistry |
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1982-95 |
Professor, Department of Biology, The Johns Hopkins University |
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1983 |
Work on "hypothermophilic bacteria" commences |
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1995 |
Dies of heart attack in Randallstown, Maryland (May 14) |
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1996 |
International Conference on Protein Folding and Design, honoring Anfinsen (April 23-26) |
Awards and Prizes
Rockefeller Foundation Public Service Award |
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International Union of Pure and Applied Chemistry Travel Grant |
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Guggenheim Foundation Fellowship for Travel |
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National Science Foundation Travel Award |
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Weizmann Institute of Science (Rehovot, Israel), Honorary Fellow |
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All Souls College, Visiting Fellow |
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American Society of Biological Chemists, President |
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Nobel Prize in Chemistry (with Stanford Moore and William H. Stein) |
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National Library of Medicine Medal |
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William Lloyd Evans Memorial Award, Ohio State University |
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Editorial Boards
Advances in Protein Chemistry, Editor |
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Biopolymers |
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Journal of Biological Chemistry |
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Proceedings of the National Academy of Sciences |
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Honorary Degrees
Adelphi University |
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Brandeis University |
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Georgetown University |
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Gustavus Adolphus College |
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New York Medical College |
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Providence College |
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Swarthmore College |
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University of Las Palmas (Canary Islands) |
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University of Naples |
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University of Pennsylvania |
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Yeshiva University |
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Lectureships
Baird Hastings Memorial Lecture, Harvard Medical School |
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EMBO Lecturer for Sweden |
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Harvey Lecture? |
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Jubilee Lecture, British Biochemical Society |
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Kelly Lecture, Purdue University |
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Kempner Lectureship, University of Texas Medical Branch (Galveston) |
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Leon Lecture, University of Pennsylvania |
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Mathers Lectures, Indiana University (Bloomington) |
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Naff Lectures, University of Kentucky (Lexington) |
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Memberships
American Academy of Arts and Sciences |
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American Philosophical Society |
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American Society of Biological Chemists |
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National Academy of Sciences |
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National Institute on Aging, board of scientific counselors |
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Pontifical Academy of Science |
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Royal Danish Academy |
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Professorships
Center of Marine Biotechnology (University of Maryland), faculty affiliate |
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Harvard Medical School, Department of Biological Chemistry |
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Johns Hopkins University, Department of Biology |
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Return to the Table of Contents
The Christian Anfinsen Papers consist of 16 linear feet and three oversize boxes. Sheila O'Neill, former Curator of Modern Manuscripts Collection, began receiving the materials in early 1998, and in December 1999, HMD secured a deed of gift from Libby Anfinsen. A second accession of materials was received in June 2000. In 2004, Mrs. Anfinsen loaned a number of commemorative materials to the library for copying.
The collection consists primarily of materials related to Anfinsen's scientific career and is geared toward Anfinsen's research activities both inside and outside the laboratory. These scientific materials include professional correspondence with organizations or individuals, mostly from the 1980s; a long run of laboratory notebooks from 1961-1981, with most of the material by individuals other than Anfinsen; a collection of Anfinsen's publications from the 1950s to the 1990s; and a photographic collection containing portraits of Anfinsen's colleagues and an assortment of slides used for his scientific publications and lectures. Aside from a small number of clippings and articles, the collection contains few materials related to Anfinsen's receiving the 1972 Nobel Prize for Chemistry.
The collection also contains a series of personal and biographical information. Most of this material includes biographical sketches, articles, awards, and items related to several memorial services held for Anfinsen. During his leisure time Anfinsen spent many hours sailing, and the collection contains a few sailing logs and photographs from various excursions.
Nearly half of the collection consists of Anfinsen's professional correspondence files from the 1960s to the 1990s related to his scientific activities. Another one-third of the collection is made up of laboratory notebooks from the late-1960s and 1970s. The rest of the materials consist of publications, slides, photographs, and biographcial materials. The bulk of the materials in the collection thus came from the late-1960s to the early 1990s. Despite the small amount of early materials and Nobel Prize related items, this collection effectively documents Anfinsen's late 1960s - 1970s laboratory work and professional activities.
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Restrictions
Restrictions
Collection is not restricted. Contact the Reference Staff for information regarding access. For online customer service, please visit http://www.nlm.nih.gov/contacts/custserv-email.html.
Copyright
Copyright to the collection was trensferred to the public domain. Contact the Reference Staff for details regarding rights. For online customer service, please visit http://www.nlm.nih.gov/contacts/custserv-email.html.
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These terms are indexed in the National Library of Medicine's online catalog LocatorPlus. Researchers wishing to find related materials should search the catalog using these terms. |
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MeSH Subjects |
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Amino Acid Sequence |
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Chromatography |
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Genetics, Biochemical |
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Human Rights |
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Interferons |
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Peptides |
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Plasmodium knowlesi |
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Protein Conformation |
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Thermococcaceae |
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Corporate Names |
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Affinity Chromatography and Biological Recognition Symposium |
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American Philosophical Society |
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American Scandinavian Foundation |
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Carlsbergfondet, Copenhagen |
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Committee of Concerned Scientists |
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Harvard Medical School |
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Johns Hopkins University |
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National Academy of Sciences (U.S.) |
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National Institute of Arthritis and Musculoskeletal and Skin Diseases (U.S.) |
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National Institute of Health (U.S.) |
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National Institute on Aging (U.S.) |
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Swarthmore College |
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University of Pennsylvania |
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Weizmann Institute of Science |
Return to the Table of Contents
Portions of the Collection have been digitized and are available at: http://profiles.nlm.nih.gov
Anfnsen, Christian. Christian Anfinsen papers. 1939-1999. Located in: Modern Manuscripts Collection, History of Medicine Division, National Library of Medicine, Bethesda, MD.; MS C 496.
Gift of Libby Anfinsen; received between 1998 and 1999. Materials found in boxes 41 and 42 are copies of two- and three-dimensional commemorative items Libby Anfinsen temporarily loaned to the National Library of Medicine in 2004.
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Personal and Biographical Series, 1939-1996 2.0 linear feet
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This series contains materials related to the personal life of Christian Anfinsen. The series consists of four subseries covering biographical reminiscences, articles about Anfinsen, awards, and sailing. There is little on Anfinsen's childhood or pre-college years. Instead, much of the material in this series recalls Anfinsen's accomplishments as a scientist through various biographical sketches and dedications. These items are primarily from the 1960s through the mid-1990s. In addition to scientific biographical information, the sailing materials in this series reveal aspects of Anfinsen's favorite leisure activity. Other personal accounts from life outside of the laboratory are few. |
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The first subseries contains biographical sketches, curricula vitae, and several folders of material from memorial services following Anfinsen's death in 1995. The second subseries includes various articles about Anfinsen's life, mostly focusing on his scientific accomplishments. These accounts include a 1964 article by Anfinsen describing his college years at Swarthmore, Nobel Prize articles, and assorted clippings spanning the 1950s through the 1990s. The next subseries is a collection of awards, honorary degrees, and other tributes Anfinsen received throughout his lengthy career. Some of these items are kept with the oversize materials. Also located here are programs from two of the scientist's lectures. The fourth subseries consists of materials documenting Anfinsen's favorite leisure activity, sailing. When outside of the laboratory, Anfinsen spent many hours sailing, and this subseries contains sailing logs, sailing charts, and details sailing his ship the Good Girl. Photographs from several sailing excursions as well as other personal images can be found in the photographs and slides series. |
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Box |
Folder |
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I.1 Biographical, n.d; 1995-1999 |
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1 |
1 |
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Biographical Sketches |
1 |
2 |
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Curricula Vitae |
1 |
3 |
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Genealogy chart of scientists |
1 |
4 |
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Who's Who Correspondence |
1 |
5 |
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Albert Einstein Quote Kept by Anfinsen |
41 |
1 |
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Curriculum vita, [1995] |
1 |
6 |
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Eulogy Remarks, 16 May 1995 |
1 |
7 |
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Memorial Service, Johns Hopkins University, 10 September 1995 |
1 |
8 |
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Memorial Garden Dedication, Weizmann Institute, November 1995 |
1 |
9 |
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Christian Anfinsen Memorial, 22 April 1996 |
1 |
10 |
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In Memorium Address, Pontifical Academy of Science, 22 October 1996 |
1 |
11 |
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Obituaries |
41 |
2 |
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Biographical memoir, December 1996 |
41 |
3 |
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Historical marker, 1 October 1999 |
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I.2 Articles about Anfinsen, 1951-1996 |
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41 |
4 |
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The NIH Record, 5 March 1951 |
41 |
5 |
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Newspaper clippings, 1953-1979 |
41 |
6 |
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Swarthmore College Bulletin, May 1960 |
41 |
7 |
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Medical World News, 12 October 1962 |
1 |
12 |
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Swarthmore Remembered, 1964 |
41 |
8 |
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NIH publication, 1965 |
41 |
9 |
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The NIH Record, 13 June 1967 |
1 |
13 |
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Nobel Prize, 1972 |
1 |
14 |
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Swarthmore College Bulletin, Alumni Issue, December 1972 |
1 |
15 |
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Articles, 1973-1987 |
41 |
10 |
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Swarthmore College class of 1937 reunion, April 1987 |
1 |
16 |
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Articles, 1990-1996 |
1 |
17 |
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Newspaper clippings, 1970-1995 |
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I.3 Awards, Honors, and Lectures, 1939; 1961-1995; n.d. |
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41 |
11 |
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Sigma Xi, 18 January 1939 |
41 |
12 |
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American Scandinavian Foundation, 6 May 1939 |
41 |
13 |
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Sports Illustrated Silver Anniversary All-America Award, December 1961 |
Map Drawer 7 |
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Election to the National Academy of Sciences, 23 April 1963 |
41 |
14 |
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Purdue University lecture, March 1964 |
41 |
15 |
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NIH lecture, 21 October 1964 |
42 |
1 |
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Honorary degrees, 1965-87 |
42 |
2 |
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Department of Health, Education, and Welfare service awards, [n.d.], 9 April 1965 |
41 |
16 |
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Georgetown University commencement, 5 June 1967 |
41 |
17 |
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New York Medical College commencement, 3 June 1969 |
42 |
3 |
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Weizmann Institute honorary fellowship, November 1969 |
42 |
4 |
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Nobel Prize diploma, 10 October 1972 |
41 |
18 |
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Congratulatory correspondence [Nobel Prize], October-November 1972 |
41 |
19 |
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American Philosophical Society membership, 25 April 1975 |
41 |
20 |
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Nobel conference, 1-2 October 1975 |
40 |
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William Lloyd Evans Memorial Award, Ohio State University [portfolio], 1980 |
41 |
21 |
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Albany Medical College award and citation, March 1984 |
41 |
22 |
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Adelphi University citation and photograph, 17 May 1987 |
41 |
23 |
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Pioneer in Science Award, 29 April 1990 |
42 |
5 |
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Morris Brown College award, April 1991 |
42 |
6 |
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Ira Pastan and Harold E. Varmus NIH posters, 1993-1995 |
Map Drawer 7 |
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NIH Scientist Emeritus, n.d. |
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I.4 Sailing, 1972-1989 |
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1 |
18 |
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Allied Boat Company |
1 |
19 |
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Bermuda Sailing Chart |
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Sailing Logs, 1972-1989 |
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1 |
20 |
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Ocean Passage, 1972 |
1 |
21 |
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Sailing Route From North Carolina to South Carolina, November 1973 |
1 |
vol. |
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Government Notebook, November 1974 |
1 |
vol. |
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Government Notebook, October 1977 |
1 |
22 |
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Account of Dismasting, [ca. 1989] |
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Correspondence, 1965-1999
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The material in this series consists of Anfinsen's professional correspondence with individuals and organizations, discussing a wide range of subjects. Although there are some files from the late-1960s and 1970s, the majority come from the last decade and a half of Anfinsen's life, after he retired from NIH and had become a professor at Johns Hopkins University. Divided into four subseries, alphabetical, chronological, recommendations, and peer reviews, the arrangement reflects Anfinsen's filing system. The content of this series reflects Anfinsen's professional activities outside of the laboratory. The files contain materials from various conferences, including lecture notes and class notes from his tenure with Johns Hopkins University. Some files document his support of certain political and humanitarian causes, such as Committee of Concerned Scientists. Correspondence with the Weizmann Institute of Science (Israel) and the other editors of "Advances in Protein Chemistry" shows his longtime association with both endeavors. This series contains chronological files that provide ample documentation of Anfinsen's many correspondents. As an editor and scholar, Anfinsen collected a number of recommendation files and peer reviews. Because of their sensitive nature, some of these items in this series are restricted. |
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The alphabetical files make up the first of the four subseries. Retaining their alphabetical order, these files refer to Anfinsen's correspondence with organizations, individuals, events, places, or other subjects. The larger topics covered include humanitarian work, conference materials, affiliations with private businesses, patent applications, editorial board responsibilities, and work with several colleges and universities. This subseries also contains several name files, but the second subseries, the chronological files provides fuller documentation of Anfinsen's many correspondents. These files begin in the mid-1960s and conclude with correspondence from Libby Anfinsen, dating from 1995-1999. There is no name index but some of the correspondence is duplicated in the first subseries. The third subseries contains alphabetically arranged recommendation letters from Anfinsen in support of colleagues or students. The fourth subseries consists of alphabetically files containing peer reviews. These files include Anfinsen's peer reviews for "Advances in Protein Chemistry" and other journals, as well as peer review of his own publications. All of the four subseries contain some restricted material. |
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Box |
Folder |
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Alphabetical Files, 1983-1991 |
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2 |
1 |
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ABC [American Business Cancer] Research Foundation, 1983-1986 |
2 |
2 |
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ABC [American Business Cancer] Research Foundation, 1987-1988 |
2 |
3 |
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Academic Press, 1983-1991 |
2 |
4 |
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Adelphi University, 1984-1987 |
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Advances in Protein Chemistry |
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2 |
5 |
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1983-1984 |
2 |
6 |
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1985 March - September |
2 |
7 |
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1985 November - December |
2 |
8 |
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1986 |
2 |
9 |
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1987 January-June |
2 |
10 |
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1987 July-December |
2 |
11 |
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1988 January-April |
2 |
12 |
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1988 May-July |
2 |
13 |
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1988 August |
2 |
14 |
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1988 September-December |
3 |
1 |
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1989 January-June |
3 |
2 |
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1989 July-December |
3 |
3 |
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1990 January-April |
3 |
4 |
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1990 May-June |
3 |
5 |
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1990 July-December |
3 |
6 |
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1991-1995 |
3 |
7 |
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Advances in Protein Seminar, Fall 1991 |
3 |
8 |
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Affinity Chromatography and Biological Recognition Symposium, 1983 |
3 |
9 |
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Affinity Chromatography and Biological Recognition Symposium, 1987 |
3 |
10 |
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Affinity Chromatography and Biological Recognition Symposium, 1991 |
3 |
11 |
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Affinity Chromatography and Biological Recognition Symposium, 1995 |
3 |
12 |
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American Academy of Arts and Sciences, Symposium in Honor of John Edsall, 31 October 1992 |
3 |
13 |
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American Association for the Advancement of Science, 1988 |
3 |
14 |
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American Cyanamid Company, 1985 |
3 |
15 |
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American Federation of Labor, 1984 |
3 |
16 |
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American Peptide Society, 1976-1994 |
3 |
17 |
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American Philosophical Society, 1976-1994 |
3 |
18 |
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American Society for Biochemistry and Molecular Biology, 1991 |
3 |
19 |
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Annenberg Hazen Workshop, Aspen, July-August 1984 |
3 |
20 |
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Baird Hastings Lectures, 1983-1993 |
3 |
21 |
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Bar-Ilan University, 1984-1990 |
3 |
22 |
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Bard College, 1983-1990 |
4 |
1 |
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Biological Research Support Grants Committee, 1984-1990 |
4 |
2 |
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Brooklyn College Lecture, 23 March 1988 |
4 |
3 |
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Celebrating the Mentors Symposium, NIH, March 1987 |
4 |
4 |
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Center for History of Chemistry, University of Pennsylvania [part 1], 1981-1983 |
4 |
5 |
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Center for History of Chemistry, University of Pennsylvania [part 2], 1981-1983 |
4 |
6 |
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Center for History of Chemistry, University of Pennsylvania [part 3], 1981-1983 |
4 |
7 |
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Center of Marine Biotechnology, University of Maryland, 1988-1991 |
4 |
8 |
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Cohen, Jack, 1990 |
4 |
9 |
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Committee of Concerned Scientists, Inc., 1983-1990 |
4 |
10 |
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Committee of 100 for Tibet, 1991-1992 |
4 |
11 |
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Congressional Names and Addresses, 1985 |
4 |
12 |
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Contributions of Chemical Biology to the Biomedical Sciences Symposium, NIH, 30-31 March 1981 |
4 |
13 |
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Cornell University, Lecture, October 1993 |
4 |
14 |
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Current Comments, 1981-1985 |
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Daltex Medical Sciences, Inc., 1984-1995 |
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4 |
15 |
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1984-1989 |
4 |
16 |
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1990 March-May |
4 |
17 |
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1990 June-November |
4 |
18 |
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1991 |
4 |
19 |
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1992-1995 |
4 |
20 |
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Dupont, 1983-1984 |
4 |
21 |
|
Paul Ehrlich Lecture, NIH, n.d. |
5 |
2 |
|
Erikson, R.L., 1985 |
5 |
3 |
|
Federation of American Scientists, 1990 |
5 |
4 |
|
Georgetown University, Honorary Degree, 1967 |
5 |
5 |
|
Goldberger, Robert F., 1988-1989 |
5 |
6 |
|
Gordon Research Conference, Newport, 1989 |
5 |
7 |
|
Goteborg Lecture, Thermophiles Seminar, 3 December 1991 |
5 |
8 |
|
Gustavus Adolphus College, 1982-1983 |
5 |
9 |
|
Harvard Medical School, 1990 |
5 |
10 |
|
Howard Hughes Medical Institute, 1987 |
5 |
11 |
|
Human Genome Project, 1988-1993 |
5 |
12 |
|
Human Rights Committee, 1980-1983 |
5 |
13 |
|
Human Rights Committee, 1984-1989 |
5 |
14 |
|
Industrial Liaison, 1984 |
5 |
15 |
|
Institute for Research on Aging, 1984-1991 |
5 |
16 |
|
Interdisciplinary Science Reviews, 1989 |
5 |
17 |
|
International Conference on Protein Folding and Design, NIH, 23-26 April 1996 |
5 |
18 |
|
International Congress of Biochemistry, Jerusalem, 4-9 August 1991 |
5 |
19 |
|
International Symposium on Advances in Medicine, Las Palmas, 1993 |
5 |
20 |
|
Japan, 1984-1988 |
5 |
21 |
|
Jewish National Fund, Trees for Israel, 1995 |
|
|
|
Johns Hopkins University, 1978-1995 |
|
|
|
|
|
|
|
6 |
22 |
|
|
Classes and Class Notes, 1978-1995 |
5 |
23 |
|
|
Department of Biology, 1983 |
5 |
24 |
|
|
Laboratory Equipment 1985-1989 |
5 |
25 |
|
|
Laboratory Grants, 1986-1990 |
5 |
26 |
|
|
Laboratory Safety Report, 1985 |
5 |
27 |
|
|
Students and Student Work, 1988 |
5 |
28 |
|
Journal of Molecular Recognition, 1987 |
5 |
29 |
|
Komoryia, Akira, 1983-1986 |
5 |
30 |
|
Kon-kuk University Lectures, Korea, 1988 |
5 |
31 |
|
Lasker Medical Research Awards, 1984 |
6 |
1 |
|
Lectures and Lecture Notes, 1983-1991 |
6 |
2 |
|
Lectures and Lecture Notes, undated |
6 |
3 |
|
Limited Partnership, 1984-1985 |
|
|
|
Lindau, Meeting of Nobel Laureates, 1989-1995 |
|
|
|
|
|
|
|
6 |
4 |
|
|
1989 |
6 |
5 |
|
|
1990 |
6 |
6 |
|
|
1993 |
6 |
7 |
|
|
1995 |
6 |
8 |
|
Luxembourg Television, International Medica Productions, 1990 |
6 |
9 |
|
Frank Mathers Lectureship in Chemistry, Indiana University, 1974 |
6 |
10 |
|
Millenium Committee of New York, 1997-1999 |
6 |
11 |
|
Misrock, Leslie, 1985-1986 |
6 |
12 |
|
National Academy of Sciences, 1984-1992 |
6 |
13 |
|
National Cancer Institute, 1984 |
|
|
|
National Institute on Aging, 1989-1990 |
|
|
|
|
|
|
|
6 |
14 |
|
|
1989 May-September |
6 |
15 |
|
|
1989 October-December |
6 |
16 |
|
|
1990 January-May |
6 |
17 |
|
|
1990 July-October |
6 |
18 |
|
National Institutes of Health, Alumni Association, 1988 |
6 |
19 |
|
National Science Foundation, 1989-1995 |
6 |
20 |
|
New York Medical College, Honorary Degree, 1969 |
6 |
21 |
|
Nobel Committee, 1985-1994 |
6 |
22 |
|
Nominations |
6 |
23 |
|
Novo Industries, 1989-1990 |
7 |
1 |
|
Office of Naval Research, 1986 |
7 |
2 |
|
Partners in the Research Enterprise Conference, University of Pennsylvania, December 1982 |
|
|
|
Patents, 1984-1995 |
|
|
|
|
|
|
|
7 |
3 |
|
|
1984-1985 |
7 |
4 |
|
|
[part 1], 1988 |
7 |
5 |
|
|
[part 2], 1988 |
7 |
6 |
|
|
1989-1990 |
7 |
7 |
|
|
1991 |
7 |
8 |
|
|
1992 January-July |
7 |
9 |
|
|
1992 August-December |
7 |
10 |
|
|
1993 January-June |
7 |
11 |
|
|
1993 July-December |
7 |
12 |
|
|
1994 January-May |
7 |
13 |
|
|
1994 June-December |
7 |
14 |
|
|
1995 |
8 |
1 |
|
Perkin-Elmer University Donation Program, 1985 |
8 |
2 |
|
Photographs Requested, 1983-1988 |
8 |
3 |
|
Ponnamperuma, Cyril, 1991 |
8 |
4 |
|
Pontifical Academy of Sciences, 1981-1990 |
8 |
5 |
|
Pontifical Academy of Sciences, 1994 |
8 |
6 |
|
Price, Charles, 1983-1989 |
8 |
7 |
|
Proceedings of the National Academy of Sciences, 1987-1988 |
8 |
8 |
|
Proceedings of the National Academy of Sciences, 1990-1995 |
8 |
9 |
|
Protein Engineering Symposium, Stony Brook, New York [part 1], May 1985 |
8 |
10 |
|
Protein Engineering Symposium, Stony Brook, New York [part 2], May 1985 |
8 |
11 |
|
Protein Research Symposium, Taiwan, December 1993 |
8 |
12 |
|
The Protein Society, 1989-1995 |
|
|
|
Receptron, Inc., 1988-1994 |
|
|
|
|
|
|
|
8 |
13 |
|
|
1988-1992 |
8 |
14 |
|
|
1993 January-April |
8 |
15 |
|
|
1993 June-September |
8 |
16 |
|
|
1994 |
8 |
17 |
|
Reunion of Nobel Laureates, Paris, January 1988 |
8 |
18 |
|
Alexander Rich Symposium, Massachusetts Institute of Technology, June 1994 |
8 |
19 |
|
Roche Institute of Molecular Biology, 1983-1987 |
8 |
20 |
|
Sakharov Committee, 1984 |
8 |
21 |
|
Scientists Role in American Society, Lecture, Pomona College and Claremont College, California, n.d. |
8 |
22 |
|
Shulman, Seth, 1989 |
8 |
23 |
|
Theobald Smith Award, 1984 |
8 |
24 |
|
Stetten, DeWitt, Jr., 1979-1983 |
8 |
25 |
|
Swarthmore College, 1964-1985 |
8 |
26 |
|
Taiwan, Lecture, 1988 |
9 |
1 |
|
Takara Biomedicals, 1991-1993 |
9 |
2 |
|
Trends in International Collaboration and Movement of Bioscientists, NIH, 1983 |
9 |
3 |
|
Union of Concerned Scientists, ca. 1975 |
9 |
4 |
|
University of Chicago Press, 1985 |
9 |
5 |
|
University of Naples, Lecture, October 1994 |
9 |
6 |
|
University Science Partners, 1986-1987 |
9 |
7 |
|
Francis Preston Venable Lecture, University of North Carolina, Chapel Hill, 27 February 1969 |
|
|
|
Weizmann Institute, 1983-1991 |
|
|
|
|
|
|
|
9 |
8 |
|
|
1983-1985 |
9 |
9 |
|
|
1986-1987 |
9 |
10 |
|
|
1988-1991 |
9 |
11 |
|
|
Association of Friends Meeting, Germany, 1983 |
9 |
12 |
|
|
Honors Committee, 1985-1987 |
9 |
13 |
|
Elie Wiesel Foundation for Humanity, 1987-1990 |
9 |
14 |
|
Young, Michael, 1993-1994 |
9 |
15 |
|
Zichini, Antonio, 1988-1990 |
|
|
Chronological Files, 1965-1999 |
|
|
|
|
|
9 |
16 |
|
1965-1969 |
9 |
17 |
|
1970-1973 |
9 |
18 |
|
1974-1976 |
9 |
19 |
|
1977-1978 |
9 |
20 |
|
1979-1981 |
10 |
1 |
|
1982 |
10 |
2 |
|
1983 February-June |
10 |
3 |
|
1983 July-August |
10 |
4 |
|
1983 September-December |
10 |
5 |
|
1984 January-March |
10 |
6 |
|
1984 April-June |
10 |
7 |
|
1984 July-October |
10 |
8 |
|
1984 November-December |
10 |
9 |
|
1985 January-March |
10 |
10 |
|
1985 April-July |
10 |
11 |
|
1985 August-December |
10 |
12 |
|
1986 January-February |
10 |
13 |
|
1986 March-May |
10 |
14 |
|
1986 June-December |
11 |
1 |
|
1987 January-March |
11 |
2 |
|
1987 April-June |
11 |
3 |
|
1987 July-August |
11 |
4 |
|
1987 September-October |
11 |
5 |
|
1987 November-December |
11 |
6 |
|
1988 January-February |
11 |
7 |
|
1988 March-April |
11 |
8 |
|
1988 May |
11 |
9 |
|
1988 June |
11 |
10 |
|
1988 July |
11 |
11 |
|
1988 August |
11 |
12 |
|
1988 September-October |
12 |
1 |
|
1988 November |
12 |
2 |
|
1988 December |
12 |
3 |
|
1989 January-February |
12 |
4 |
|
1989 March-May |
12 |
5 |
|
1989 June-August |
12 |
6 |
|
1989 September |
12 |
7 |
|
1989 October-December |
12 |
8 |
|
1990-1993 |
12 |
9 |
|
1994-1995 |
12 |
10 |
|
1996-1999 |
|
|
Recommendation Files |
|
|
|
|
|
13 |
1 |
|
A |
13 |
2 |
|
B |
13 |
3 |
|
C |
13 |
4 |
|
D |
13 |
5 |
|
E |
13 |
6 |
|
F |
13 |
7 |
|
G |
13 |
8 |
|
Ha |
13 |
9 |
|
Ho |
13 |
10 |
|
I-J |
13 |
11 |
|
Johns Hopkins University Medical School |
14 |
1 |
|
K |
14 |
2 |
|
La |
14 |
3 |
|
Le-Lu |
14 |
4 |
|
Ma |
14 |
5 |
|
Mo |
14 |
6 |
|
N-O |
14 |
7 |
|
Pa |
14 |
8 |
|
Pe-Po |
14 |
9 |
|
R |
14 |
10 |
|
Sch [part 1] |
14 |
11 |
|
Sch [part 2] |
14 |
12 |
|
Se-Sw |
14 |
13 |
|
T-U-V |
14 |
14 |
|
W-X-Y-Z |
|
|
Peer Reviews |
|
|
|
|
|
15 |
1 |
|
Appella, Ettore |
15 |
2 |
|
Chen, Thomas |
15 |
3 |
|
Colwell, Rita |
15 |
4 |
|
Edidin, Michael |
15 |
5 |
|
Englander, Walter |
15 |
6 |
|
Funakoshi, Susuma |
15 |
7 |
|
Huang, P.C. |
15 |
8 |
|
Laderman, Kenneth |
15 |
9 |
|
Maier, Robert |
15 |
10 |
|
Meltzer, Stephen |
15 |
11 |
|
Moudrianakis, Van |
15 |
12 |
|
Ohno, Motonori |
16 |
1 |
|
Pecht, Israel |
16 |
2 |
|
Porath, Jerker |
16 |
3 |
|
Rosenberg, Steven |
16 |
4 |
|
Rotter, Varda |
16 |
5 |
|
Tsang, Tom |
16 |
6 |
|
Vallee, Bert |
16 |
7 |
|
Youle, Richard |
Return to the Table of Contents
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|
Laboratory Notes and Notebooks, 1959-1985 3.75 linear feet
|
|
This series contains approximately 40 laboratory notebooks and a few loose laboratory notes. Although these scientific notes come from Anfinsen's laboratory or from his colleagues, only a few are in Anfinsen's hand. The materials come from the late-1960s and extend into the early 1980s. These notes document various scientific experiments such as studies on chromatography, electrophoresis, and interferon assays. Since only a few of the notebook binders had names on the binder and nearly all items were dated, the series was arranged chronologically. For preservation considerations, materials were removed from binders and put into folders. Some of the items are fragile and should be handled with extra care. These notebooks provide important documentary evidence of Anfinsen's forty-year scientific career. |
|
|
|
|
Box |
Folder |
17 |
1 |
Chromatography Experiments, 1959-1965 |
17 |
2 |
[part 1], 1966 |
17 |
3 |
[part 2], 1966 |
17 |
4 |
Synthesis w/Tyrosine [part 1], 1966 |
17 |
4 |
Synthesis w/Tyrosine [part 2], 1966 |
17 |
4 |
Synthesis w/Tyrosine [part 3], 1966 |
17 |
|
1966 |
17 |
7 |
A.A.A., Rotary Dispersion, Analysis [part 1], 1966-1967 |
17 |
8 |
A.A.A., Rotary Dispersion, Analysis [part 2], 1966-1967 |
17 |
9 |
A.A.A., Rotary Dispersion, Analysis [part 3], 1966-1967 |
17 |
10 |
[Motonori] Ohno [Book] B, ca. 1966-1967 |
17 |
11 |
'67 [part 1], 1967 |
17 |
12 |
'67 [part 2], 1967 |
17 |
13 |
'67 [part 3], 1967 |
17 |
14 |
'67 [part 4], 1967 |
18 |
1 |
'67 Concurrent Data and Summar of Peptides, 1967 |
18 |
2 |
Merrifield '67 [part 1], 1967 |
18 |
3 |
Merrifield '67 [part 2], 1967 |
18 |
4 |
Merrifield '67 [part 3], 1967 |
18 |
5 |
Merrifield '67 [part 4], 1967 |
18 |
6 |
Merrifield '67 [part 5], 1967 |
18 |
7 |
[Motonori] Ohno Book C [part 1], 1967 |
18 |
8 |
[Motonori] Ohno Book C [part 2], 1967 |
18 |
9 |
1967 [Motonori] Ohno [Book] I [Part 1], 1967 |
18 |
10 |
1967 [Motonori] Ohno [Book] I [Part 2], 1967 |
18 |
11 |
1967 [Motonori] Ohno [Book] I [Part 3], 1967 |
18 |
12 |
1967 [Motonori] Ohno [Book] I [Part 4], 1967 |
18 |
13 |
'68 [part 1], 1968 |
19 |
1 |
'68 [part 2], 1968 |
19 |
2 |
'68 [part 3], 1968 |
19 |
3 |
'68 [part 4], 1968 |
19 |
4 |
'68 [part 5], 1968 |
19 |
5 |
'68 [part 6], 1968 |
19 |
6 |
'68 [part 7], 1968 |
19 |
7 |
'68 [part 8], 1968 |
19 |
8 |
'68 [part 9], 1968 |
19 |
9 |
P2 Experiment, [ca. 1968] |
19 |
10 |
St.Aureus M - '68 [part 1], 1968 |
19 |
11 |
St.Aureus M - '68 [part 2], 1968 |
19 |
12 |
St.Aureus M - '68 [part 3], 1968 |
19 |
13 |
"The Wind Up: M- on Fogg: Media", ca. 1968 |
20 |
1 |
Miscellaneous Experiments, 1968-1969 |
20 |
2 |
Synthesis of B-Poc Amino Acids, [ca. 1969] |
20 |
3 |
[Motonori] Ohno [Book] E - '69-'70 [part 1], 1969-1970 |
20 |
4 |
[Motonori] Ohno [Book] E - '69-'70 [part 2], 1969-1970 |
20 |
5 |
'70 - '71 [part 1], 1970-1971 |
20 |
6 |
'70 - '71 [part 2], 1970-1971 |
20 |
7 |
'70 - '71 [part 3], 1970-1971 |
20 |
8 |
'70 - '71 [part 4], 1970-1971 |
20 |
9 |
'70 - '71 [part 5], 1970-1971 |
20 |
10 |
'70 - '71 [part 6], 1970-1971 |
20 |
11 |
'70 - '71 [part 7], 1970-1971 |
20 |
12 |
'72 Fox [part 1], 1972 |
20 |
13 |
'72 Fox [part 2], 1972 |
21 |
1 |
'72 Fox [part 3], 1972 |
21 |
2 |
Interferon '72 [part 1], 1972 |
21 |
3 |
Interferon '72 [part 2], 1972 |
21 |
4 |
Interferon '72 [part 3], 1972 |
21 |
5 |
Interferon '72 [part 4], 1972 |
21 |
6 |
'73 [part 1], 1973 |
21 |
7 |
'73 [part 2], 1973 |
21 |
8 |
'73 [part 3], 1973 |
21 |
9 |
Interferon #2 '73 [part 1], 1973 |
21 |
10 |
Interferon #2 '73 [part 2], 1973 |
21 |
11 |
Interferon #2 '73 [part 3], 1973 |
21 |
12 |
Interferon #2 '73 [part 4], 1973 |
21 |
13 |
Sheep Book '73 [part 1], 1973 |
21 |
14 |
Sheep Book '73 [part 2], 1973 |
21 |
15 |
Vilcek V1-V7, ca. 1973 |
22 |
1 |
991-31 - 991-83 Loose Lab Notes, [part 1], 1973-1974 |
22 |
2 |
991-31 - 991-83 Loose Lab Notes, [part 2], 1973-1974 |
22 |
3 |
991-31 - 991-83 Loose Lab Notes, [part 3], 1973-1974 |
22 |
4 |
IF (Chuck) '74 [part 1], 1974 |
22 |
5 |
IF (Chuck) '74 [part 2], 1974 |
22 |
6 |
IF (Chuck) '74 [part 3], 1974 |
22 |
7 |
3H IF I (Vilcek) 1974 [part 1], 1974 |
22 |
8 |
3H IF I (Vilcek) 1974 [part 2], 1974 |
22 |
9 |
3H IF I (Vilcek) 1974 [part 3], 1974 |
22 |
10 |
* IF II (Vilcek) 1974 [part 1], 1974 |
22 |
11 |
*IF II (Vilcek) 1974 [part 2], 1974 |
22 |
12 |
'74 IF III, 1974 |
22 |
13 |
UR - 1 1974 [part 1], 1974 |
22 |
14 |
UR - 1 1974 [part 2], 1974 |
22 |
15 |
IF (Havell) IV, 1974-1975 |
22 |
16 |
'75 [part 1], 1975 |
22 |
17 |
'75 [part 2], 1975 |
23 |
1 |
'75 [part 3], 1975 |
23 |
2 |
'75 [part 4], 1975 |
23 |
3 |
'76 P.J.B. Electrophoresis Gells etc. [part 1], 1976 |
23 |
4 |
'76 P.J.B. Electrophoresis Gells etc. [part 2], 1976 |
23 |
5 |
'76 P.J.B. Electrophoresis Gells etc. [part 3], 1976 |
23 |
6 |
'76 P.J.B. Electrophoresis Gells etc. [part 4], 1976 |
23 |
7 |
Tabor '76 [part 1], 1976 |
23 |
8 |
Tabor '76 [part 2], 1976 |
23 |
9 |
UR 5 '76 [part 1], 1976 |
23 |
10 |
UR 5 '76 [part 2], 1976 |
23 |
11 |
'77, 1977 |
23 |
12 |
'77 [part 1], 1977 |
23 |
13 |
'77 [part 2], 1977 |
23 |
14 |
'78 [part 1], 1978 |
23 |
15 |
'78 [part 2], 1978 |
23 |
16 |
'78 IF Assays Results [part 1], 1978 |
24 |
1 |
'78 IF Assays Results [part 2], 1978 |
24 |
2 |
'78 IF Assays Results [part 3], 1978 |
24 |
3 |
P.B.J. vol. 1 [part 1], April '78 - March '79 |
24 |
4 |
P.B.J. vol. 1 [part 2], April '78 - March '79 |
24 |
5 |
P.B.J. vol. 1 [part 3], April '78 - March '79 |
24 |
6 |
P.B.J. vol. 1 [part 4], April '78 - March '79 |
24 |
7 |
P.B.J. vol. 1 [part 5], April '78 - March '79 |
24 |
8 |
P.B.J. vol. 1 [part 6], April '78 - March '79 |
24 |
9 |
[part 1], 1979 |
24 |
10 |
[part 2], 1979 |
24 |
11 |
[part 3], 1979 |
24 |
12 |
[part 4], 1979 |
24 |
13 |
[part 5], 1979 |
24 |
14 |
[part 6], 1979 |
24 |
15 |
IF Vol. 2 ISM [part 1], March '79 |
25 |
1 |
IF Vol. 2 ISM [part 2], March '79 |
25 |
2 |
IF Vol. 2 ISM [part 3], March '79 |
25 |
3 |
'79 NIHG-25/Affinity Started 4/79 [part 1], 1979 |
25 |
4 |
'79 NIHG-25/Affinity Started 4/79 [part 2], 1979 |
25 |
5 |
Hyb[rid] RNAse '79, 1979 |
25 |
6 |
'79 Radioactivity Records [part 1], 1979 |
25 |
7 |
'79 Radioactivity Records [part 2], 1979 |
25 |
8 |
[part 1], 1980 |
25 |
9 |
[part 2], 1980 |
25 |
10 |
[part 3], 1980 |
25 |
12 |
Sequencing Exp[eriment], 1980 |
25 |
13 |
Analytical Gel, 1 July 1981 |
25 |
14 |
Interferon Assays [part 1], 1981 |
25 |
15 |
Interferon Assays [part 2], 1981 |
25 |
16 |
Loose Miscellaneous Lab Notes, 1963-1985 |
Return to the Table of Contents
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Reprints and Research Publications, 1950-1993 2.0 linear feet
|
|
This series is divided into two subseries: the scientific publications of Anfinsen and those of his close colleagues. These publications begin in the 1950s and reach into the 1990s. Along with copies of nearly two hundred Anfinsen reprints, this series includes his Nobel address, abstracts, and drafts of articles. The reprints are arranged by Anfinsen's numbering system, and can be deciphered by using the master list of reprints and numbers (see Appendix B). These reprints account for approximately ninety percent of the articles he published during his forty years of scientific work. This series also contains a collection of publications by others including dissertations directed by Anfinsen and publications from the Pontifical Academy of Sciences. In total, this series contains the majority of Anfinsen's prolific body of writings and research. |
|
|
|
|
|
|
|
The first subseries features a lengthy run of Anfinsen's scientific articles from 1954-1993, as well as some of his other published and unpublished works. The master list of reprints and numbers indicates which articles are contained within the collection. In most cases there are two copies of each reprint. The second subseries features four dissertations from Anfinsen's doctoral students, a run of Pontifical Academy of Sciences publications mostly from the 1980s, a Weizmann Institute Directory from 1990, and a history of the National Heart, Lung, and Blood Institute. |
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|
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Box |
Folder |
|
|
Anfinsen Publications, 1954-1993 |
|
|
|
|
|
26 |
1 |
|
Abstracts |
26 |
2 |
|
Bibliographies |
|
|
|
Book Excerpts |
|
|
|
|
|
|
|
26 |
3 |
|
|
Anfinsen, CB, Redfield RR, "On the structural basis of rivonuclease activity" 128-43, in Molecular Structure and Biological Specificity, ed. Linus Paulling and Harvey A. Itano (Washington, D.C.: American Institute of Biological Sciences) 1957 |
26 |
4 |
|
|
Anfinsen, CA, The Molecular Basis of Evolution (New York: Wiley), 1959 |
26 |
5 |
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"Studies on the Principles that Govern the Folding of Protein Chains", Nobel Lecture, 100-119 in Les Prix Nobel en 1972 (Nobel Foundation 1973) 11 December 1972 |
26 |
6 |
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Drafts of Articles |
26 |
7 |
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Master List of Reprints and Numbers |
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Numbered Reprints |
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26 |
8 |
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1-10 |
26 |
9 |
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11-16 |
26 |
10 |
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17-20 |
26 |
11 |
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21-26 |
26 |
12 |
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27-30 |
26 |
13 |
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31-40 |
26 |
14 |
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41-44 |
26 |
15 |
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45-50 |
27 |
1 |
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51-55 |
27 |
2 |
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56-60 |
27 |
3 |
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61-70 |
27 |
4 |
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71-80 |
27 |
5 |
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81-90 |
27 |
6 |
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91-100 |
27 |
7 |
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101-110 |
27 |
8 |
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111-120 |
27 |
9 |
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121-130 |
27 |
10 |
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131-140 |
27 |
11 |
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141-145 |
27 |
12 |
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146-150 |
27 |
13 |
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151-160 |
27 |
14 |
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161-170 |
28 |
1 |
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171-180 |
28 |
2 |
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181-185 |
28 |
3 |
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186-190 |
28 |
4 |
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191-200 |
28 |
5 |
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201-210 |
28 |
6 |
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211-220 |
28 |
7 |
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221-230 |
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Publications by Others, 1950-1992 |
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Dissertations |
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29 |
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Theodore Peters, Jr., "Studies in Serum Albumin Production in Vitro" Ph.D. diss., Harvard University 1950 |
29 |
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James Allen Olson, "The Crystallization and Characterization of L (/) Glutamic Acid Dehydrogenase of Beef Liver" Ph.D. diss., Harvard University, 1951 |
29 |
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Daniel Steinberg, "Studies on the Mechanism of Ovalbumin Synthesis" Ph.D. diss., Harvard University, 1951 |
29 |
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Frederick Howard White, Jr., "Studies on the Tyrosine Oxidase System of Rat Liver (Part I); Reductive Cleavage of Disulfide Bridges in Ridonuclease" Ph.D. diss., University of Wisconsin, 1957 |
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Pontifical Academy of Sciences Publications |
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30 |
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Scripta Varia 49, Science and the Modern World, part II, Proceedings of the Symposium on Science and the Modern World Plenary Session, 11-13 October 1978, 1978 |
30 |
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Scripta Varia 52, Science and the Modern World, part III, Proceedings of the Symposium on Science and the Modern World Plenary Session, 11-13 November 1979, 1979 |
30 |
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Scripta Varia 61, Study Week on the Interaction of Parasitic Disease and Nutrition, October 22-26, 1985, edited by Carlos Chagas and Gerald T. Keusch, 1986 |
30 |
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Scientarium Documenta 21, G.B. Marini-Bettolo, Historical Aspects of the Pontifical Academy of Sciences, October 28, 1986, 1986 |
30 |
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Scientarium Documenta 15, Study Week on the Interaction of Parasitic Diseases and Nutrition, October 22-26, 1986, Summary, 1987 |
30 |
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Scientarium Documenta 18, Working Group on Molecular Mechanisms of Carcinogenic and Antitumor Activity, October 21-25, 1986, Conclusions, 1987 |
30 |
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Scripta Varia 72, Working Group on Immunology, Epidemiology and Social Aspects of Leprosy, May 28-June 1, 1984, edited by Carlos Chagas, 1988 |
30 |
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Scientiarum Documenta 23, Study Week on a Modern Approach to the Protection of the Environment, November 2-7, 1987, Conclusions, 1988 |
30 |
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Giovanni Marchesi S.I., "La Pontificia Accademia Delle Scienze Luogo D'Incontro Tra Ragione E Fede" La Civilta' Cattolica, 6-20 August 1988 |
31 |
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Scripta Varia 75, Study Week on A Modern Approach to the Protection of the Environment, November 2-7, 1987 edited by G.B. Marini-Bettolo, 1988 |
31 |
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Scripta Varia 79, Brain Research and the Mind-Body Problem: Epistemological and Metaphysical Issues, Proceedings of a Round Table Discussion Held at the Pontifical Academy of Science on 25 October 1988, edited by Giuseppe Del Re, 1988 |
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Other |
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30 |
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National Institutes of Health, A Salute to the Past: A History of the National Heart, Lung, and Blood Institute. Bethesda: NIH, 1987 |
31 |
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The Weizmann Institute of Science, Scientific Activities, 1990, ed. Peter L. Strange. Israel: Achdut Press, Ltd, 1990 |
Return to the Table of Contents
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Photographs and Slides, 1939-1994 1.6 linear feet
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This series contains photographs and slides divided roughly into two aspects of Anfinsen's life, the personal and professional. These designations make up two subseries, arranged by subject. Personal items include portraits of Anfinsen, sailing photographs and slides, and snapshots following his 1979 wedding. Some of these personal photographs were taken from the personal and biographical series. The professional subseries contains photographs from awards ceremonies, conferences, and laboratory work. There is also a collection of portraits of Anfinsen's scientific colleagues, some with signatures, dates, and inscriptions on the front. Nearly all of the individuals have been identified, allowing for the alphabetical arrangement by the individuals' last names. Anfinsen also collected several binders of scientific slides which he used for various presentations and conferences. There appears to be no particular order to the slides, so the items were transferred to slide pages and kept in their original arrangement. Together these photographs and slides document both Anfinsen's scientific career and personal life. |
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Box |
Folder |
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Personal, 1972 - 1990s |
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32 |
1 |
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Portraits of Anfinsen, 1990s |
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Sailing, 1972-1976 |
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32 |
2 |
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[part 1] 1972-1973 |
32 |
3 |
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[part 2] 1972-1973 |
34 |
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Slides June 1976 |
32 |
4 |
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Wedding Ceremony, 1979 |
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Professional |
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Awards, 1969, 1973, 1982 |
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32 |
5 |
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Weizmann Institute of Science, Honorary Fellow, 1969 |
41 |
25 |
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Unknown event, [ca. 1970s] |
32 |
6 |
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University of Pennsylvania, Honorary Degree, 1973 |
41 |
26 |
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Unknown event and Yeshiva University dinner [ca. 1980s] |
32 |
7 |
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Yeshiva University, Honorary Degree, 1982 |
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Conference Photographs, 1960s-1980s |
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32 |
8 |
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ca. 1960s |
32 |
9 |
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ca. 1970s |
32 |
10 |
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ca. 1980s |
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Conference Slides |
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35 |
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University of Naples Lecture, October 1994 |
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Laboratory Work, 1939-1994 |
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32 |
11 |
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Carlsberg Laboratory, Copenhagen, 1939-1955 |
32 |
12 |
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NIH Laboratory Workers [probably National Institute of Arthritis and Metabolic Diseases], [ca. 1960s] |
41 |
24 |
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Anfinsen at work, [ca. 1970s] |
32 |
13 |
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NIH Laboratory Workers [probably National Institute of Arthritis and Metabolic Diseases], [ca. 1970s] |
32 |
14 |
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Johns Hopkins University Laboratory, March 1990 |
41 |
27 |
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Portraits by Richard T. Nowitz, 1991 |
41 |
28 |
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Protein, n.d. |
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Overheads and negatives |
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32 |
15 |
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Chemical Chains |
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Portraits of Scientists |
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32 |
16 |
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Anson |
32 |
17 |
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Ball, Eric, 1962 |
32 |
18 |
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Berger, Arieh, September 1972 |
32 |
19 |
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Berzer, Seymour |
32 |
20 |
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Blout, Elkan |
32 |
21 |
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Brown, R. |
33 |
1 |
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Desnuelle, Pierre |
33 |
2 |
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Doty, Paul M. |
33 |
3 |
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Edsall, John T. |
33 |
4 |
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Ernst |
33 |
5 |
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Francis, from Ramsey Hospital, Cambridge |
33 |
6 |
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Fruton, Joseph S. |
33 |
7 |
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Green, David |
33 |
8 |
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Handler, Philip, 1963 |
33 |
9 |
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Haskings, A. Baird, January k1958 |
33 |
10 |
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Holter, Heinz |
33 |
11 |
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Hotchkiss, Rollin |
33 |
12 |
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Hvidt, Aase |
33 |
13 |
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Kalkar, Herman |
33 |
14 |
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Kanen, Martin |
33 |
15 |
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Katchullski-Katzir, Ephraim |
33 |
16 |
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Lifson, Schneor |
33 |
17 |
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Linderstrom-Lang, Kaj |
33 |
18 |
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Liperman, Fritz, October 1962 |
33 |
19 |
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Lowry, Oliver H. |
33 |
20 |
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Meister, Alton |
33 |
21 |
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Merrifield, Bruce |
33 |
22 |
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Moore, Stanford, 1964 |
33 |
23 |
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Narita, Kozo |
33 |
24 |
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Neuroth, Hans |
33 |
25 |
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Rich, Alexander |
33 |
26 |
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Richards, Fred |
33 |
27 |
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Sanger, Fred, 1962 |
33 |
28 |
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Satu, Herbert |
33 |
29 |
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Schachman, Howard K. |
33 |
30 |
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Scheraga, Harold |
33 |
31 |
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Stein, William H. |
33 |
32 |
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Unidentified Scientists |
40 |
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Valler, M. |
33 |
33 |
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Waley, Stephen G. |
33 |
34 |
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Wilson, James |
33 |
35 |
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Zamecnik, Paul |
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Slides for Presentations |
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34 |
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Blue Binder [10 pages of slides] |
34 |
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Black Binder [4 pages of slides] |
35 |
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Brown Binder [5 pages of slides] |
35 |
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Loose slides [10 pages of slides] |
36 |
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From plastic pages [16 pages of slides] |
Return to the Table of Contents
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Audiovisual, 1948-1990 0.4 linear feet
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This series contains audiovisual materials in two subseries. All the tapes in this subseries are copies dubbed from originals loaned by Libby Anfinsen. The first subseries consists of a short home movie of Anfinsen's family during a 1948 trip to Norway. This early footage was originally on an 8mm tape. The second subseries contains four tapes, three videotapes and one audiocassette, documenting parts of Anfinsen's professional career. The first videotape is from a 1972 roundtable discussion featuring Anfinsen and other Nobelists. The second videotape is an interview with Anfinsen concerning his work in protein research. The third tape in this subseries is an audiotape containing Anfinsen's 1983 lecture given at Gustavus Adolphus College. The written transcript of this lecture can be found in the Gustavus Adolphus College folder in the correspondence series. The final videotape is a 1990 interview with Anfinsen at his home in Baltimore, Maryland. |
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Box |
Folder |
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Personal |
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37 |
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"Norsk-Americanere Besoker Bergern Sommeren," [North American Visitor on Summer Vacation in Bergen, Norway], VHS, 5:55, 1948 |
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Professional |
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37 |
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"Science and Man: Round Table Discussion", VHS 40 Minutes, 1972 |
37 |
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"Christian Anfinsen on 'Good Girl' -- Pre Nobel Interview", VHS, 20 minutes, 1972 |
37 |
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"Bioengineering: Short Term Optimism and Long Term Risk", Nobel XIX Conference, Gustavus Adolphus College, Audiocassette 30 Minutes, 4-5 October 1983 |
37 |
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"Die Stillen Stars; Nobelpreistragen Privat Gesehen-Christian Anfinsen," [The Quiet Stars: The Private Lives of Nobel Prize Winners - Christian Anfinsen] VHS, 30 minutes, 1990 |
Return to the Table of Contents
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Oversize Materials
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Oversize materials are items that were too large to house in normal sized Hollinger boxes and are kept separately for preservation considerations. Materials are kept in large oversize boxes, except for the posters and awards which are kept loosely. These items consist of two commemorative plates, posters, a wire sculpture of an amino acid structure, and Anfinsen's typewriter. |
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Box |
Folder |
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Commemorative Plates, 1970s; 1972 |
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38 |
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14 inch plaster plate, green with a white circular profile of Alfred Nobel in the center, inscribed with 22 signatures, [ca. 1972] |
39 |
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12 inch ceramic plate, white with DHEW [Department of Health, Education, and Welfare] logo in orange and black, inscribed with 36 signatures, [ca. late 1970s] |
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Posters |
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Map Drawer 7 |
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Harold Varmus, "Genes, Mice, and Cancer" at Weizmann Institute [3], 1995 |
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Miscellaneous |
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40 |
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"Coat hanger" RNA Structure |
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Anfinsen's Typewriter |
Return to the Table of Contents
Appendix: Photographs Loaned for Scanning, not Included in Physical Collection
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Christian Anfinsen sitting on parents' lap at age 1, (1917) |
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Christian Anfinsen in NIH portrait, [ca. 1950s] |
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Christian Anfinsen with his father and child, [ca. 1950s] |
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Christian Anfinsen in tuxedo with drink and cigarette, [ca. 1960s] |
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Christian Anfinsen in NIH portrait, [ca. 1960s] |
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Christian Anfinsen in laboratory adjusting valve, [ca. 1960s] |
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Christian Anfinsen in Lindau [Germany] restaurant, [ca. 1970s] |
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Christian Anfinsen in NIH portrait, ca. 1970s |
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Attendees of the Symposium on Biopolymers and Biotechnology, Weizmann Institute, [ca. 1986] |
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Christian Anfinsen with other scientist, [ca. 1970s] |
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Christian Anfinsen receiving 1972 Nobel Prize in Chemistry], (1972) |
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Christian and Libby Anfinsen, (May 1979) |
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Christian Anfinsen in his office, [ca. late 1970s] |
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Christian Anfinsen with "coat hanger" RNA structure, [ca. 1980s] |
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Libby Anfinsen shaking hands with Pope John Paul II, [ca. 1980s] |
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Christian Anfinsen shaking hands with Pope John Paul II, [ca. 1980s] |
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Christian Anfinsen at a Bar-Ilan University dinner, [ca. 1980s] |
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Christian and Libby Anfinsen at Yeshiva University dinner with guests, [ca. 1980s] |
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Christian Anfinsen in horizontal portrait shot, [ca. 1980s] |
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Christian Anfinsen shaking hands with Jimmy Carter, (color) (1980) |
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Christian Anfinsen as captain of the Passage, (July 9, 1987) |
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Christian Anfinsen in Lindau [Germany] with black shirt, [ca. 1990s] |
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Christian Anfinsen in Lindau [Germany] with black suit,[ca. 1990s] |
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Christian Anfinsen in Annapolis home, [1990s] |
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Christian Anfinsen with editors of Advances in Protein Chemistry (1990) |
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Christian Anfinsen in Nice (France), (1992) |
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Christian and Libby Anfinsen in front of violet shrub, (1995) |
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Christian Anfinsen in laboratory with J. Edward Rall (vertical shot), [ca. 1970s] |
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Appendix: Master List of Reprints and Numbers
|
1. Anfinsen, C.B., Lowry, O.H. and Hastings, A.B.: Application of thefreezing-drying technique to retinal histochemistry. J. Cell. andComp. Physiol.M 20: 231-237, 1942. |
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2. Anfinsen, C.B.: The distribution of diphosphopyridine nucleotide inthe bovine retina. J. Biol. Chem. 152: 273-284, 1944. |
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3. Anfinsen, C.B.: The distribution of cholinesterase in the bovineretina. J. Biol. Chem. 152: 267-278, 1944. *(Not in collection) |
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4. Anfinsen, C.B.: A micromanometric method for the determination ofdiphosphopyridine nucleotide. J. Biol. Chem. 152: 285-291, 1944. |
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5. Ball, E.G., Anfinsen, C.B., Geiman, Q.M.; McKee, R.W. and Ormsbee, R.A.: In vitro growth and multiplication of the malaria parasite Plasmodiumknowlesi. Science 101: 542-344, 1945. |
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6. McKee, R.W., Ormsbee, R.A., Anfinsen, C.B., Geiman, Q.M. and Ball, E.G.: Studies on malarial parasites. VI. The chemistry and metabolism ofnormal and parasitized (P. knowlesi) monkey blood. J. Exp. Med.M 84:569-582, 1946. |
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7. Geiman, Q.M., Anfinsen, C.B., McKee, R.W., Ormsbee, R.A. and Ball, E.G.: Studies on malarial parasites. VII. Methods and techniques for cultivation. J. Exp. Med.34: 538-606, 1946. |
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8. Anfinsen, C.B., Geiman, Q.M., McKee, R.W., Ormsbee, B.A. and Ball, E.G.: Studies on malarial parasites. VIII. Factors affecting the growth ofPlasmodium knowlesi in vitro. J. Exp. Med. 84: 607-621, 1946. |
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9. Anfinsen, C.B.: Determination of dauterium in the gradient tube, Preparation and Measurement of Isotopic Tracers, D. Wright Wilson,Editor, J.W. Edwards, Ann Arbor, 1946. |
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10. Anfinsen, C.B. and Claff, C.L.: An extension of the cartesian divermicro respirometer technique. J. Biol. Chem. 167: 27-33, 1947. *(Not in collection) |
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11. Ball, E.G., Anfinsen, C.B., and Cooper, O.: The inhibitory action ofnapthoquinones on respirator processes. J. Biol. Chem. 168: 257-270,1947. |
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12. Anfinsen, C.B., Beloff, A., Hastings, A.B. and Solomon, A.K.: The invitro turnover of dicarboxylic amino acids in liver slice proteins.J. Biol. Chem.168: 771-772, 1947. |
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13. Anfinsen, C.B.: The inhibitory action of maphthoguinones on respiratoryprocess: the inhibition of cleavage and respiration in the eggsof Arbacia punctulata. J. Cell. and Comp. Physiol. 29: 323-332, 1947. |
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14. Solomon, A.K., Gould, R.G., and Anfinsen, C.B.: Energy of beta-radiation from S35 C14. Phys. Review 72: 1097-1100, 1947. *(Not in collection) |
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16. Ball, E.G., McKee, R.W., Anfinsen, C.B., Cruz, W.O. and Geiman, Q.M.:Studies on malarial parasites. IX. Chemical and metabolic changesduring growth and multiplication in vivo and in vitro. J. Biol.Chem. 175: 547-571, 1943. |
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17. Beloff, A., and Anfinsen, C.B.: The products of proteolysis of somepurified proteins. J. Biol. Chem. 176: 863-872, 1938. |
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18. Gould, R.G.; Hastings, A.B., Anfinsen, C.B., Rosenberg, I.N.,Solomon, A.K. and Topper, Y.J.: Metabolism of isotopic pyruvateand acetate in rabbit liver slices in vitro. J. Biol. Chem. 177: 727-731, 1949. |
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19. Hastings, A.B., Solomon, A.K, Anfinsen, C.B., Gould, R.G. andRosenberg, I.N.: Incorporation of isotopic carbon dioxide in rabbitliver glycogen in vitro. J. Biol. Chem. 177: 717-726, 1949. |
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20. Anfinsen, C. B., Beloff, A. and Solomon, A.K.: The incorporation ofradioactive carbon dioxide and acetate into liver proteins in vitro.J. Biol. Chem. 179: 1001-1013, 1949. |
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21. Buchanan, J. M., and Anfinsen, C.B.: Partial purification of aconitase.J. Biol. Chem. 180: 47-54, 1949. |
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22. Peters, T., Jr. and Anfinsen, C.B.: Production of radioactive serumalbumin by liver slices. J. Biol. Chem. 182: 171-179, 1950. |
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23. Beecher, H. K., Francis, L. and Anfinsen, C.B.: Metabolic effects ofanesthesia in man. J. Pharmacol. and Exp. Therap. 98: 38-44, 1950. |
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24. Anfinsen, C.B.: Radioactive crystalline ribonuclease. J. Biol. Chem.185: 827-831, 1950. |
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25. Peters, T.P. and Anfinsen, C.B.: Net production of serum albumin byliver slices. J. Biol. Chem. 186: 805-813, 1950. |
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26. Anfinsen, C.B. and Steinberg, D.: Studies on the biosynthesis ofovalbumin. J. Biol. Chem. 189: 739-744, 1951. |
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27. Steinberg, D. and Anfinsen, C.B.: Evidence for intermediate compoundsin ovalbumin synthesis. J. Biol. Chem. 199: 25-42, 1952. |
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28. Olson, J.A. and Anfinsen, C.B.: Crystallization and characterizationof L-glutamic acid dehydrogenase. J. Biol. Chem. 197: 67-79, 1952. |
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29. Anfinsen, C.B.: The peptic digestion of ribonuclease. J. Biol. Chem. 196:201-208, 1952. |
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30. Anfinsen, C.B., Flavin, M., Farnsworth, J.: Preliminary studies onribonuclease structure. Biochem. et Biophys. Acta 9: 468-469, 1952. |
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31. Anfinsen, C.B.; Boyle, E. and Brown, R.K.: Role of heparin in lipoproteinmetabolism. Science 115: 583-586, 1952. |
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32. Gordon, R.S., Jr. Boyle, E., Brown, R-K., Cherkes, A. and Anfinsen, C.B.:The role of serum albumin in the lipemia clearing reaction. Proc. Soc.Exp. Biol. and Med. 84: 168-170, 1953. |
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33. Anfinsen, C.B. and Horning, M.: Enzymatic degradation of the cholesterolside chain in cell-free preparations. J. Am. Chem. Soc. 75: 1511, 1953. |
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34. Brown; R.K., Boyle, E. and Anfinsen, C.B.: The enzymatic transformationof lipoproteins. J. Biol. Chem. 204: 423-434, 1953. |
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35. Olson, J.A. and Anfinsen, C.B.: Kinetic and equilibrium studies oncrystalline L-glutamic dehydrogenase. J. Biol. Chem. 202: 841-856,1952. |
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36. Hendler, R.W., Horning, M.G. and Anfinsen, C.B.: The synthesis ofradioactive L-glutamic acid. Arch. Biochem. and Biophys. 51; 470-474, 1954. |
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37. Anfinsen, C.B.: Fat metabolism. On the role of lipemia clearingfactor in lipid transport. Fat Metabolism, Johns Hopkins Press,Baltimore, 93-110, 1954. |
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38. Anfinsen, C.B., Redfield, R.R., Choate, W.L., Page, J. and Carroll, W.R.:Studies on the gross structure, cross-linkages, and terminal sequencesin ribonuclease. J. Biol. Chem. 207: 201-210, 1954. |
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39. Wang, J.H., Anfinsen, C.B. and Polestra, F.M.: The self-diffusioncoefficients of water and ovalbumin in aqueous ovalbumin solutionsat 10 degrees. J. Am. Chem. Soc. 76: 4763, 1954. |
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40. Hendler, R.W. and Anfinsen, C.B.: The incorporation of carbondioxide into both carboxyl groups of glutamic acid. J. Biol. Chem.209: 55-62, 1954. |
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41. Stadtman, T.C., Cherkes, A., and Anfinsen, C.B.: Studies on themicrobiological degradation of cholesterol. J. Biol. Chem. 206:511-523, 1954. |
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42. Anfinsen, C.B. and Kielley, W.W.: Biological oxidations. AnnualReview of Biochemistry 23: 17-54, 1954. |
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43. Anfinsen, C.B.: Physiological aspects of lipid transport. NationalResearch Council Symposium on Atherosclerosis, March, 1954. *(Not in collection) |
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44. Flavin, M., and Anfinsen, C.B.: The isolation and characterizationof cysteic acid peptides applied to the study of ovalbumin synthesis.J. Biol. Chem. 211: 375-390, 1954. |
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45. Vaughan, M. and Anfinsen, C.B.: Nonuniform labeling of insulin andribonuclease synthesized in vitro. J. Biol. Chem. 211: 367-374, 1954. |
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46. Anfinsen, C.B.: Summary - second session, National Research CouncilSymposium on Atherosclerosis, March 23, 1954. *(Not in collection) |
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47. Anfinsen, C.B.: Lipoprotein metabolism in the etiology of atherosclerosis.Minnesota Medicine 38: 767-774, 1955. |
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48. Anfinsen, C.B.: Aconitase from pig heart muscle, in Methods inEnzymology, edited by Colowick and Kaplan, Academic Press, Inc. 1955. *(Not in collection) |
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49. Anfinsen, C.B.: The inactivation of ribonuclease by restricted pepsindigestion. Biochim. et Biophys. Acta 17: 593-594, 1955. |
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50. Anfinsen, C.B., Harrington, W.F., Hvidt, Aa, Linderstrom-Lang, K.,Ottesen, M. and Schellman, J.: Studies on the structural basis ofribonuclease activity. Biochim. et Biophys. Acta 17: 141-142, 1955. *(Includes 1989 commentary) |
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51. Anfinsen, C.B.: On the structural basis of ribonuclease activity.Symposium on molecular structure and biological specificity. AmericanInstitute of Biological Sciences, Washington, D.C., October, 1955. *(Not in collection) |
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52. Anfinsen, C.B.: The limited digestion of ribonuclease with pepsin.J. Biol. Chem. 221:. 405-412, 1956. |
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53. Redfield, R.R. and Anfinsen, C.B.: The structure of ribonuclease.II. The preparation, separation and relative alignment of largeenzymatically produced fragments. J. Biol. Chem. 221: 385-404, 1956. |
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54. Steinberg, D., Vaughan, M. and Anfinsen, C.B.: Kinetic aspects ofthe assembly and degradation of proteins. Science 124: 389-395, 1956. |
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55. Anfinsen, C.B. and Redfield, R.R.: Protein structure in relation tofunction and synthesis, in Advances in Protein Chemistry Vol. XI, Academic Press, N.Y., pp. l-100, 1956. |
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56. Anfinsen, C.B.: Biochemical aspects of atherosclerosis. Fed. Proc.15: 894-899, 1956. |
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57. Anfinsen, C.B., Sela, M. and Tritch, H.: A method for the specificproteolytic cleavage of protein chains. Arch. Biochem. and Biophys.65: 156-163, 1956. |
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58. Anfinsen, C.B.: On the non-essential nature of hydrogen bondingfor the catalytic activity of ribonuclease. Compt. Rend. des Trav.du Carlsberg. Ser. Chim. 30: 13-20, 1956. |
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59. Anfinsen, C. B.: Funzione dell' eparina nel metabolismo delle lipoproteine. Estratto dai Rendicanti Dell' Istituto Superiore di Sanita. Suppl. al Vol. XIX. Roma 1956. pp. 181 196. |
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60. Sela, M. and Anfinsen, C.B.: Some spectrophotometric and polarimetricexperiments with ribonuclease. Biochim. et Biophys. Acta 24: 229-235, 1957. |
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61. Sela, M., White, F.H., Jr. and Anfinsen, C.B.: Reductive cleavageof disulfide bridges in ribonuclease. Science 125: 691-692, l957. |
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62. Steinberg, D., Vaughan, M., Anfinsen, C.B. and Gorry, J.: Preparationof tritiated proteins by the Wilzbach method. Science 126: 447-448, 1957. *(Not in collection) |
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63. Ryle, A.P. and Anfinsen, C.B.: Studies on the disulfide bridges inribonuclease. Biocheim. et Biophys. Acta 24: 633-635, 1957. |
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64. Horning, M.G., Fredrickson, D.S. and Anfinsen, C.B.: Studies on theenzymatic degradation of the cholesterol side chain. II. Requirementsof the mitochondrial system. Arch. Biochem. and Biophys. 71: 266-273, 1957. |
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65. Anfinsen, C.B.: Structural basis of ribonuclease activity. FederationProc. 16: 783-791, 1957. *(Not in collection) |
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66. Sela, M., Anfinsen, C.B. and Harrington, W.F.: The correlation ofribonuclease activity with specific aspects of tertiary structure.Biochim. et Biophys. Acta 26: 502-512, 1957. *(Not in collection) |
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67. Anfinsen, C.B.: The structure of ribonuclease in relation to itsenzymatic activity and physical properties. Symposium on ProteinStructure, Edited by Albert Neuberger, John Wiley & Sons, Inc., N. Y.1958. |
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68. Sela, M., White, F.H., Jr. and Anfinsen, C.B.: The reductive cleavageof disulfide bonds and its application to problems of protein structure.Biochim. et Biophys. Acta 31: 417-426, 1959. *(Not in collection) |
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69. Anfinsen, C. B.: Protein structure and biological activity, inA Symposium on Molecular Biology, Raymond E. Zirkle, ed., Univ ofChicago Press, Chicago, 1959. |
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70. Anfinsen, C.B., Aqvist, S.E.G., Cooke J.P., and Jonsson, B.: Acomparative study of the structures of bovine and ovine pancreaticribonucleases. J. Biol. Chem. 234: 1118-1123, 1959. |
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71. Aqvist, S.E.G. and Anfinsen, C.B.: The isolation and characterizationof ribonucleases from sheep pancreas. J. Biol. Chem. 234: 1112-1117,1959. |
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72. White, F.H. and Anfinsen, C.B.: Some relationships of structure tofunction in ribonuclease. Ann. N.Y. Acad. Sci. 81: 515-523, 1959. |
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73. White, F.H., Jr. and Anfinsen, C.B.: On the order of disulfide bondreduction in ribonuclease, in Sulfur in Proteins, Academic Press,New York, pp. 279-288, 1959. |
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74. Avigan, J. and Anfinsen, C.B.: Further observations on the structureand properties of serum lipoproteins. Biochim. Biophys. Acta 31:249-251, 1959. |
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75. Anfinsen, C. B.: Some approaches to the study of active centers. J.Cellular Comp. Physiol. 54: Suppl. 1, 215, 1959. |
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76. Katz, A.M., Dreyer, W.J. and Anfinsen, C.B.: Peptide separation bytwo-dimensional chromatography and electrophoresis. J. Biol. Chem.234: 2897-2900, 1959. |
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77. Brown, R.K., Tacey, B.C., and Anfinsen, C.B.: The reaction of porcineand ovine ribonucleases with antibody to bovine ribonuclease. Biochim.Biophys. Acta 39: 528, 1960. |
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78. Anfinsen, C.B.: The Molecular Basis of Evolution, John Wiley & Sons,Inc., New York, 1959. *(Not in collection) |
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79. Anfinsen, C.B.: and White, F.H., Jr.: The ribonucleases, occurrence,structure and properties. The Enzymes, Second ed., Academic Press,New York, 1961; pp. 95-122. |
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80. Tuve, T.W. and Anfinsen, C.B.: Preparation and properties ofspinach ribonuclease. J. Biol. Chem. 235: 3437-3441, 1960. |
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81. Anfinsen, C.B.: Genetic control of protein structure in bacteriophages.Fed. Proc. 20: 634-640, 1961. |
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82. Haber, E. and Anfinsen, C.B.: Regeneration of enzyme activity by airoxidation of reduced, subtilisin-modified ribonuclease. J. Biol. Chem.236: 422-424, 1961 |
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83. Anfinsen, C.B.: The influences of three-dimensional configuration ofthe chemical reactivity and stability of proteins. J. Polymer Sci.49: 31-49, 1961 |
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84. Anfinsen, C.B. and Haber, E.: Studies on the reduction and reformationof protein disulfide bonds. J. Biol. Chem. 236: 1361-1363, 1961. |
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85. Anfinsen, C.B.: Points of current interest in protein chemistry.Lab Invest. 10: 987-991, 1961. |
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86. Anfinsen, C.B.: Haber, E., Sela, M. and White, F.H., Jr.: The kineticsof formation of native ribonuclease during oxidation of the reducedpolypeptide chain. Proc. Nat. Acad. Sci. 47: 1309-1314, 1961. |
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87. Anfinsen, C.B.: Factors influencing the formation and maintenance ofthe secondary and tertiary structure of proteins. Presented at thePontificia Academia Scientiarum Study Week. Oct. 23-30, 1961. TheVatican. *(Not in collection) |
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88. Epstein, C.J., Goldberger, R.F., Young, D.M. and Anfinsen, C.B.: Astudy of the factors influencing the rate and extent of enzymicreactivation during reoxidation of reduced ribonuclease. Arch.Biochem. Suppl. 1: 223-231, 1962. |
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89. Anfinsen, C.B.: Some observations on the basic principles of designin protein molecules. Fifth International Congress of Biochemistry,August 10-17, 1961, Moscow. Comp. Biochem. Physiol. 4: 229, 1963.Pergamon Press. |
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90. Anfinsen, C.B., Sela, M. and Cooke, J.P.: The reversible reductionof disulfide bonds in polyalanyl ribonuclease. J. Biol. Chem. 237:1825-1831, 1962. |
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91. Haber, E. and Anfinsen, C.B.: Side chain interactions governing thepairing of half-cystine residues in ribonuclease. J. Biol. Chem.237: 1839-1844, 1962. |
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92. Potts, J.T., Berger, A., Cooke, J.P. and Anfinsen, C.B.: A reinvesti-gation of the sequence of residues eleven to eighteen in bovinepancreatic ribonuclease. J. Biol. Chem. 237: 1851-1855, 1962. |
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93. Goldberger, R.F. and Anfinsen, C.B.: The reversible masking of aminogroups in ribonuclease and its possible usefulness in the synthesisof the protein. Biochemistry 1: 401-405, 1962. |
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94. Epstein, C.J. and Anfinsen, C.B.: The reversible reduction of disulfidebonds in trypsin and ribonuclease coupled to carboxymethyl-cellulose.J. Biol. Chem. 237: 2175-2179, 1962. |
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95. Anfinsen, C.B.: Amino acid sequence as the major determinant ofstructure and function in proteins. In Gellhorn, A. and Hirschberg (Eds):Basic Problems in Neoplastic Disease. New York, ColumbiaUniv. Press, 1962, pp. 112-130. *(Not in collection) |
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96. Epstein, D.J. and Anfinsen, C.B.: Reversible reduction and reoxidationof poly-DL-alanyl trypsin. J. Biol. Chem. 237: 3464-3467, 1962. |
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97. Epstein, C.J., Anfinsen, C.B. and Sela, M.: The properties of poly-DL-alanyl chymotrypsin. J. Biol. Chem. 237: 3458-3463, 1962. |
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98. Anfinsen, C.B.: Macromolecular considerations of cellular organization.In Canadian Cancer Conference. New York, Academic Press, 1963. Vol. 5,pp. 3-9. |
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99. Anfinsen, C.B.: The tertiary structure of ribonuclease. BrookhavenSymposia in Biology 15: 184-198, 1962. *(Not in collection) |
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100. Anfinsen, C.B.: General remarks on protein structure and biosynthesis.In Symposium on Informational Macromolecules. New York, Academic Press, 1963, pp. l53-166. |
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101. Goldberger, R.F., Epstein, C.J., and Anfinsen, C.B.: Acceleration of reactivation of reduced bovine panreatic ribonuclease by a microsomal system from rat liver. J. Biol. Chem. 238: 628-635, 1963 |
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102. Epstein, C.J. and Anfinsen, C.B.: The use of gel filtration in theisolation and purification of beef insulin. Biochem. 2: 461-464, May-June 1963. |
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103. Cooke, J.P., Anfinsen, C.B. and Sela, M.: The identification of unreactive amino groups in ribonuclease and their significance toenzymatic activity. J. Biol. Chem. 238: 2034-2039, 1963. *(Not in collection) |
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104. Canfield, R.E., and Anfinsen, C.B.: Chromatography of pepsin andchymotrypsin digests of egg white lysozyme on phosphocellulose. J.Biol. Chem. 238, 2684, 1963. |
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105. Canfield, R.E. and Anfinsen, C.B.: Nonuniform labeling of egg whitelysozyme. Biochem. 2: 1073-1078, 1963. |
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106. Canfield, R.E. and Anfinsen, C.B.: Concepts and experimental approaches in the determination of the primary structure of proteins. InNeurath, H. (ed.): The Proteins. New York, Academic Press, 1963. Vol.1, pp. 311-378. |
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107. Anfinsen, C.B., Rumley, M.K., and Taniuchi, H.: Structural andenzymatic properties of the extracellular nuclease of micrococcuspyogenes. Acta Chemica Scand. 17: 270-276, 1963. |
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108. Potts, J.T., Jr., Young, D.M. and Anfinsen, C.B.: Reconstitution offully active RNase S by carboxypeptidase-degraded RNase S-peptide.J. Biol. Chem. 238: 2593-2594, 1963. |
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109. Brown, R.K., Trzpis, M.A., Sela, M. and Anfinsen, C.B.: Studies onthe antigenic structure of ribonuclease. IV. Polyalanyl ribonuclease.J. Biol. Chem. 238: 3876-3883, 1963. |
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110. Epstein, C.J., Goldberger, R.F. and Anfinsen, C.B.: The genetic control of tertiary protein structure: studies with model systems.Cold Spr. Harb. Symp. on Quant. Biol. XXVIII, 439-449, 1963. |
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111. Anfinsen, C.B.: On the possibility of predicting tertiary structurefrom primary sequence. In Sela, M. (Ed), New Perspectives in Biology.Amsterdam, The Netherlands, Elsevier Pub. Co., 1964. pp. 42-50. *(Not in collection) |
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112. Goldberger, R.F., Epstein, C.J. and Anfinsen, C.B.: Purification andproperties of a microsomal enzyme system catalyzing the reactivationof reduced ribonuclease and lysozyme. J. Biol. Chem. 239:1406-1410, 1964. |
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113. Potts, J.T., Jr., Young, D.M., Anfinsen, C.B. and Sandoval, A.:Studies on ribonuculease S. I. Limited carboxypeptidase degradationof ribonuclease S-protein and ribonuclease S-peptide: effects ofchanges in primary structure on enzymic activity. J. Biol. Chem.239: 3781-3786, 1964. |
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114. Givol, D., Goldberger, R.F. and Anfinsen, C.B.: Oxidation and disulfideinterchange in the reactivation of reduced ribonuclease. J. Biol.Chem. 239: 3114-3116, 1964. |
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115. Craven, G.R., Steers, E., Jr., and Anfinsen, C.B.: Purification,Composition, and molecular weight of the B-galactosidase of EscherichiaColi K12. J. Biol. Chem. 240: 2468-2477, 1965. |
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116. Steers, E., Jr., Craven, G.R., Anfinsen, C.B. and Bethune, J.L.:Evidence for non-identical chains in the B-galactosidase ofEscherichia coli K12. J. Biol. Chem. 240: 2478-2484, 1965. |
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117. Givol, D., DeLorenzo, F., Goldberger, R.F. and Anfinsen, C.B.:Disulfide interchange and the three-dimensional structure of proteins.Proc. Nat. Acad. Sci. 53: 676-684, 1965. *(Not in collection) |
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118. Anfinsen, C.B.: Molecular structure and the function of proteins. InAllen, J.M. (Ed): Molecular Organization and Biological Function(Modern Perspectives in Biology). New York, Harper & Row, 1966, pp. l-19. *(Not in collection) |
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119. Givol, D., Craven, G.R., Steers, E., Jr. and Anfinsen, C.B.: Effectof limited digestion by proteolytic enzymes on Escherichia coliB galactosidase. Biochem. Biophys. Acta 113: 120-125, 1966. |
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120. Steiner, R.F., DeLorenzo, F. and Anfinsen, C.B.: Enzymically-catalyzeddisulfide interchange in randomly cross-linked soy bean trypsin inhibitorJ. Biol. Chem. 240: 4648-4651, 1965. |
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121. Steers, E., Jr., Craven, G.R. and Anfinsen, C.B.: Comparison ofB-galactosidases from normal (k-o+z+) and operator constitutive(i-ocz+) strains of E. coli. Proc. Nat. Acad. Sci. 54: 1174-1181 |
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122. Korenman, S.G., Craven, G.R. and Anfinsen, C.B.: Determination ofthe carboxyl-terminal amino acid residue of the B-galactosidase ofEscherichia coli K12. Biochim. Biophys. Acta 124: 160-165, 1966. |
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123. DeLorenzo, F., Goldberger, R.F., Steers, E., Jr., Givol, D. andAnfinsen, C.B.: Purification and properties of an enzyme from beefliver which catalyzes sulfhydryl-disulfide interchange in proteins.J. Biol. Chem. 241: 1562-1567, 1966. |
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124. Heins, J.N., Suriano, J.R., Taniuchi, H. and Anfinsen, C.B.: Characterization of a nuclease produced by Staphylococcus aureus. J. Biol. Chem. 242, 1016-1020, 1967. |
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125. Taniuchi, H. and Anfinsen, C.B.: The amino acid sequence of anextracellular nuclease of Staphylococcus aureus. I. Linear order ofthe fragments produced by cleavage with cyanogen bromide. J. Biol.Chem. 241: 4366-4385, 1966. |
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126. Anfinsen, C.B.: The formation of the tertiary structure of proteins.Harvey Lectures, Series 61, 1967. Academic Press, Inc., New York, p. 95. |
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127. Fuchs, S., DeLorenzo, F. and Anfinsen, C.B.: Studies on the mechanismof the enzymic catalysis of disulfide interchange in proteins. J.Biol. Chem. 242: 298-402, 1967. |
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128. DeLorenzo, F., Fuchs, S. and Anfinsen, C.B.: Characterization of apeptide fragment containing the essential half-cystine residue of amicrosomal disulfide interchange enzyme. Biochem. 5: 3961-3965, 1966. *(Not in collection) |
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129. Cuatrecasas, P., Fuchs, S., and Anfinsen, C.B.: Catalytic propertiesand specificity of the extracellular nuclease of Staphylococcus aureus.J. Biol. Chem. 242: 1541-1547, 1967. |
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130. Cuatrecasas, P., Fuchs, S., and Anfinsen, C.B.: The binding ofnucleotides and calcium to the extracellular nuclease of Staphylococcusaureus: studies by gel filtration. J. Biol. Chem. 242: 3063-3067,1967. |
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131. Taniuchi, H., Anfinsen, C.B. and Sodja, A.: The amino acid sequenceof an extracellular nuclease of Staphylococcus aureus. II. The aminoacid sequences of tryptic and chymotryptic peptides. J. Biol. Chem.242: 4736-4751, 1967. |
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132. Taniuchi, H., Anfinsen, C.B. and Sodja, A.: The amino acid sequence ofan extracellular nuclease of Staphylococcus aureus, V8. III. Completeamino acid sequence. J. Biol. Chem. 242: 4752-4758, 1967. |
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133. Cuatrecasas, P., Fuchs, S. and Anfinsen, C.B.: The interaction ofnucleotides with the active site of staphylococcal nuclease:spectrophotometric studies. J. Biol. Chem. 242: 4759-4767, 1967. |
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134. Fuchs, S., Cuatrecasas, P. and Anfinsen, C.B.: An improved method forthe purification of staphylococcal nuclease. J. Biol. Chem. 242:4768-4770, 1967. |
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135. Taniuchi, H., Anfinsen, C.B. and Sodja, A.: Nuclease-T: an activederivative of staphylococcal nuclease composed of two noncovalentlybonded peptide fragments. Proc. Nat. Acad. Sci. U.S.A. 58: 1235-1242, 1967. |
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136. Anfinsen, C.B., Ontjes, D., Ohno, M., Corley, L. and Eastlake, A.:The synthesis of protected peptide fragments of a staphylococcalnuclease. Proc. Nat. Acad. Sci. U.S.A. 58: 1806-1811, 1967. |
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137. Ohno, M. and Anfinsen, C.B.: Removal of protected peptides byhydrazinolysis after solid phase synthesis. J. Am. Chem. Soc. 89:5994-5995, 1967. |
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138. Cuatrecasas, P., Edelhoch, H. and Anfinsen, C.B.: Fluorescence studiesof the interaction of nucleotides with the active site of the nucleaseof Staphylococcus aureus. Proc. Nat. Acad. Sci. U.S.A. 58: 2043-2050, 1967. |
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139. Cuatrecasas, P., Fuchs, S. and Anfinsen, C.B.: The effect of acompetitive inhibitor on the acetylation of tyrosyl and lysyl residuesof staphylococcal nuclease. Biochim. Biophys. Acta 159: 417-419, 1968. |
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140. Cusumano, C.L., Taniuchi, H., and Anfinsen, C.B.: Staphylococcalnuclease (Foggi strain). I. Order of cyanogen bromide fragments anda "fourth" histidine. J. Biol. Chem. 243: 4769-4777, 1968. |
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141. Taniuchi, H. and Anfinsen, C.B.: Steps in the formation of activederivatives of staphylococcal nuclease during trypsin digestion. J.Biol. Chem. 243: 4778-4786, 1968. |
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142. Cuatrecasas, P., Fuchs, S. and Anfinsen, C.B.: The tyrosyl residuesat the active site of staphylococcal nuclease: modifications bytetranitromethane. J. Biol. Chem. 243: 4787-4798, 1968. |
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143. Cuatrecasas, P., Taniuchi, H., Anfinsen, C.B. and Ontjes, D.: Thestructural basis of the catalytic function of staphylococcal nuclease.Brookhaven Symp. Biol. 21: 172-200, 1968. |
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144. Anfinsen, C.B.: Spontaneous formation of the three-dimensionalstructure of proteins. Proc. 27th Symp. Soc. Study of Devel. & Growth,June 19-21, 1968, Ithaca, pp. l-20. |
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145. Fuchs, S., Cuatrecasas, P., Ontjes, D.A. and Anfinsen, C.B.:Correlation between the antigenic and catalytic properties ofstaphylococcal nuclease. J. Biol. Chem. 244: 943-950, 1969. |
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146. Anfinsen, C.B.: Characterization of staphylococcal nuclease and thestatus of studies on its chemical synthesis. Proc. 5th Int. Symp.Chem. of Natural Products, July 8-13, 1968. London. Pure and AppliedChem. 17: 461-487, 1968. |
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147. Cuatrecasas, P., Wilchek, M. and Anfinsen, C.B.: Selective enzymepurification by affinity chromatography. Proc. Nat. Acad. Sci. 61:636-643, 1968. |
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148. Cuatrecasas, P., Fuchs, S. and Anfinsen, C.B.: Crosslinking ofaminotyrosyl residues in the active site of staphylococcal nuclease.J. Biol. Chem. 244: 406-412, 1969. |
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149. Ontjes, D.A. and Anfinsen, C.B.: Solid phase synthesis of apolypeptide sequence from staphylococcal nuclease. Proc. 1st Amer.Peptide Symp., August 11-15, New Haven, Conn. 1968. |
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150. Omenn, G.S. and Anfinsen, C.B.: Solid phase peptide coupling. J.Am. Chem. Soc. 90, 6571-6572, 1968. |
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151. Cuatrecasas, P., Wilchek, M. and Anfinsen, C.B.: StaphylococcalNuclease: on the size and specificity of the active site. Science162: 1491-1493, 1968. |
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152. Moravek, L., Anfinsen, C.B., Cone, J.L. and Taniuchi, H.: The largescale preparation of an extracellular nuclease of Staphylococcusaureus. J. Biol. Chem. 244: 497-499, 1969. |
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153. Schechter, A.N., Moravek, L. and Anfinsen, C.B.: Suppression ofhydrogen exchange in staphylococcal nuclease by ligands. Proc. Nat.Acad. Sci. 61: 1478-1493, 1968. |
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154. Kato, I. and Anfinsen, C.B.: On the stabilization of ribonuclease-S-protein by ribonuclease-S-peptide. J. Biol. Chem. 244: 1004-1007,1969. |
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155. Cuatrecasas, P., Milchek, M. and Anfinsen, C.B.: The action ofstaphylococcal nuclease on synthetic substrates. Biochem. 8: 2277-2284, 1969. |
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156. Taniuchi, H. and Anfinsen, C.B.: An experimental approach to thestudy of the folding of staphylococcal nuclease. J. Biol. Chem.244: 3864-3875, 1969. |
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157. Cuatrecasas, P., Wilchek, M. and Anfinsen, C.B.: Affinity labelingof the active site of staphylococcal nuclease. Reactions withbromoacetylated substrate analogues. J. Biol. Chem. 244: 4316-4329, 1969. |
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158. Schechter, A.N., Moravek, L. and Anfinsen, C.B.: Hydrogen exchangein proteins as a measure of solvent exclusion due to ligands:nuclease and myoglobin. J. Biol. Chem. 244: 4981-4988, 1969. |
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159. Taniuchi, H., Moravek, L. and Anfinsen, C.B.: Ligand-induced resistance of staphylococcal nuclease and nuclease-T to proteolysis by subtilisin, a-chymotrypsin and thermolysin. J. Biol. Chem. 244: 4600-4606, 1969. |
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160. Ontjes, D.A. and Anfinsen, C.B.: Solid phase synthesis of a 42residue fragment of staphylococcal nuclease: properties of a semi-synthetic enzyme. Proc. Nat. Acad. Sci. 64: 428-435, 1969. |
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161. Kato, I. and Anfinsen, C.B.: Purification of synthetic RNase-S-peptide derivatives by specific complex formation on columns of RNase-R-protein bound to agarose. J. Biol. Chem. 244: 5849-5866, 1969. |
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162. Anfinsen, C.B. and Corley, L.G.: An active variant of staphylococcalnuclease protected carboxyl-terminal tetradecapeptide sequence ofstaphylococcal nuclease. J. Am. Chem. Soc. 91: 6842-6846, 1969. |
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163. Ohno, M., Eastlake, A., Ontjes, D.A. and Anfinsen, C.B.: Synthesisof a fully protected carboxyl-terminal tetradecapeptide sequence ofstaphylococcal nuclease. J. Am. Chem. Soc. 91: 6842-6846, 1969. *(draft) |
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164. Omenn, G.S., Ontjes, D.A. and Anfinsen, C.B.: Fractionation ofantibodies against staphylococcal nuclease on Sepharose immunoadsorbents.Nature. 225: 189-190, 1970. |
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165. Ontjes, D.A. and Anfinsen, C.B.: Synthetic studies of structure-function relationships in staphylococcal nuclease: synthetic analoguesof fragment P2. J. Biol. Chem. 244: 6316-6322, 1969. |
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166. Omenn, G.S., Cuatrecasas, P. and Anfinsen, C.B.: Studies of thearomatic circular dichroism of staphylococcal nuclease. Proc. Nat.Acad. Sci. 64: 923-930, 1969. |
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167. Schechter, A.N., Chen, R.F. and Anfinsen, C.B.: The kinetics of thefolding of staphylococcal nuclease. Science 167: 886-887, 1970. |
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168. Omenn, G.S., Fontana, A. and Anfinsen, C.B.: Modification of thesingle tryptophan residue of staphylococcal nuclease by a new mildoxidizing agent. J. Biol. Chem. 245: 1895-1902, 1970. |
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169. Anfinsen, C.B., Ontjes, D.A. and Chaiken, I.M.: Synthetic analoguesof a biologically active fragment of staphylococcal nuclease. Proc.10th European Symp. Peptides 1969. |
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170. Omenn, G.S., Ontjes, D.A. and Anfinsen, C.B.: Immunochemistry ofstaphylococcal nuclease. I. Physical, enzymatic, and immunologicalstudies of chemically modified derivatives. Biochem. 9: 304-312,1970. |
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171. Omenn, G.S., Ontjes, D.A. and Anfinsen, C.B.: Immunochemistry ofstaphylococcal nuclease. II. Inhibition and binding studies withsequence fragments. Biochem. 2: 313-321, 1970. |
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172. Chaiken, I.M. and Anfinsen, C.B.: A study of the role of histidineresidue 46 in staphylococcal nuclease by solid phase peptide synthesis.J. Biol. Chem. 245: 2337-2341, 1970. |
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173. Cuatrecasas, P. and Anfinsen, C.B.: Affinity chromatography. Methods in Enzymology, vol. XXII, New York, Academic Press. 1971, p. 345-378. |
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174. Ohno, M. and Anfinsen, C.B.: Partial enzymic deprotection in thesynthesis of a protected octapeptide bearing a free terminal carboxylgroup. J. Am. Chem. Soc. 92: 4098-4102, 1970. |
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175. Chaiken, I.M. and Anfinsen, C.B.: A solid phase synthetic study ofstructure-function relationships in the amino-terminal region ofstaphylococcal nuclease. J. Biol. Chem. 245: 4718-4723, 1970. |
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176. Chaiken, I.M. and Anfinsen, C.B.: A solid phase synthetic study ofthe active site region of staphylococcal nuclease-T. J. Biol. Chem.246: 2285-2290, 1971. |
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177. Taniuchi, H. and Anfinsen, C.B.: Simultaneous formation of twoalternative enzymically active structures by complementation of twooverlapping fragments of staphylococcal nuclease. J. Biol. Chem.246: 2291-2301, 1971. |
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178. Anfinsen, C.B., Schechter, A.N. and Taniuchi, H.: Some aspects ofthe structure of staphylococcal nuclease. Part II. Studies insolution. Cold Spr. Harb. Symp. Quant. Biol. XXXVI: 249-255, 1971. *(not in collection) |
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179. Cuatrecasas, P. and Anfinsen, C.B.: Affinity chromatography. Ann.Review of Biochem. 40: 259-278, 1971. |
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180. Anfinsen, C.B., Cuatrecasas, P. and Taniuchi, H.: Staphylococcalnuclease, chemical properties and catalysis. The Enzymes, Vol. IV.New York, Academic Press, Inc., 1971. pp. 177-204. |
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181. Izumiya, N. and Anfinsen, C.B.: Synthesis of phenylalanyl-arginyl-leucyl-aspartic acid: a model study of the coupling of arginine-terminal tryptic fragments of proteins. Arch. Biochem. Biophys. 144:237-244, 1971. |
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182. Cone, J.L., Cusumano, C.L., Taniuchi, H. and Anfinsen, C.B.:Staphylococcal nuclease (Foggi strain). II. The amino acid sequence.J. Biol. Chem. 246: 3103-3110, 1971. |
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183. Epstein, H.F., Schechter, A.N., Chen, R.F. and Anfinsen, C.B.: Thefolding of staphylococcal nuclease: kinetic studies of two processesin acid renaturation. J. Mol. Biol. 60: 499-508, 1971. |
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184. Arnon, R., Maron, E., Sela, M. and Anfinsen, C.B.: Antibodiesreactive with native oysozyme elicited by a completely syntheticantigen. Proc. Nat. Acad. Sci. U.S.A. 68: 1450-1455, 1971. |
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185. Anfinsen, C.B.: Synthetic analogeus of staphylococcal nuclease:studies of activity and conformation. Proc. 23rd Int. Cong. of Pureand Applied Chemistry, July 1971, Boston, Mass. *(also in Japanese) |
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186. Parikh, I., Corley, L. and Anfinsen, C.B.: Semi-synthetic analoguesof an enzymically active complex formed between two overlappingfragments of staphylococcal nuclease. J. Biol. Chem. 246: 7392-7397, 1971. |
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187. Taniuchi, H., Davies, D.R., and Anfinsen, C.B.: A comparison of theX-ray diffraction patterns of crystals of reconstituted nuclease-Tand of native staphylococcal nuclease. J. Biol. Chem. 247: 3362-3364, 1972. |
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188. Zeiger, A. and Anfinsen, C.B.: Progress of the classical synthesisof "fragment P2" (residues 6-47) of staphylococcal nuclease-T. Prog.Peptide Research Vol. 2, pp. 307-316, 1972. |
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189. Corley, L., Sachs, D.H. and Anfinsen, C.B.: Rapid solid-phasesynthesis of bradykinin. Biochem. Biophys. Res. Comm. 47. 1353-1359, 1972. |
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190. Anfinsen, C.B.: The formation and stabilization of protein structure.The Sixth Jubilee Lecture. Biochem. J. 128: 737-749, 1972. |
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191. Sachs, D.H., Schechter, A.N., Eastlake, A. and Anfinsen, C.B.:Inactivation of staphylococcal nuclease by the binding of antibodiesto a distinct antigenic determinant. Biochemistry 11: 4268-4273,1972. |
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192. Zeiger, A. and Anfinsen, C.B.: Synthesis of a fully protectedheptacosapeptide norleucine analogue corresponding to positions 20-47of the primary structure of staphylococcal nuclease. J. Am. Chem.Soc. 95: 880-886, 1973. |
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193. Sachs, D.H., Schechter, A., Eastlake, A. and Anfinsen, C.B.: Antibodiesto a distinct antigenic determinant of staphylococcal nuclease. J.Immunol. 109: 1300-1310, 1972. |
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194. Sachs, D.H., Schechter, A., Eastlake, A. and Anfinsen, C.B.: An immunologic approach to the conformational equilibria of polypeptides. Proc.Nat. Acad. Sci. U.S.A. 69: 3790-3794, 1972. |
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195. Sanchez, G.R., Chaiken, I.M. and Anfinsen, C.B.: Structure-functionrelationships at the active site of nuclease-T'. J. Biol. Chem. 248:3653-3659, 1973. |
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196. Fisher, W.R., Taniuchi, H. and Anfinsen, C.B.: On the role of hemein the formation of the structure of cytochrome c. J. Biol. Chem.248: 3188-3195, 1973. |
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197. Anfinsen, C.B.: Studies on the principles that govern the foldingof protein chains. Les Prix Nobel En 1972. *(Not in collection) |
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198. Anfinsen, C.B.: Principles that govern the folding of protein chains.Science 181: 223-230, 1973. (Nobel Lecture). |
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199. Peters, T., Taniuchi, H. and Anfinsen, C.B.: Affinity chromatographyof serum albumin with fatty acids immobilized on agarose. J. Biol.Chem. 248: 2447-2451, 1973. |
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200. Dunn, B.M., DiBello, C. and Anfinsen, C.B.: The pH-dependence of thesteady state kinetics parameters for staphylococcal nuclease catalyzedhydrolysis of deoxythymidine-d'-phosphate-5'-p-nitrophenylphosphatein H20 and D20. J. Biol. Chem. 248: 4769-4774, 1973. |
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201. Furie; B., Eastlake, A., Schechter, A.N. and Anfinsen, C.B.: Theinteraction of the lanthanide ions with staphylococcal nuclease.J. Biol. Chem. 248: 5821-5825, 1973. |
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202. Fuchs, S., Sela, M. and Anfinsen, C.B.: Nuclease-coated bacteriophage:a sensitive tool for studying antigenic reactivity of syntheticsequence fragments. Arch. Biochem. Biophys. 154: 601-605, 1973. |
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203. Dunn, B.M., Anfinsen, C.B. and Shrager, R.I.: Kinetics of Woodward'sreagent K hydrolysis and reaction with staphylococcal nuclease. J.Biol. Chem. 249: 3717-3723, 1974. |
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204. Furie, B., Schechter, A.N., Sachs, D.H. and Anfinsen, C.B.: Antibodiesto the unfolded form of a helix-rich region in staphylococcal nuclease.Biochemistry 13: 1561-1566, 1974. |
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205. Eastlake, A., Sachs, D.H., Schechter, A.N. and Anfinsen, C.B.: Bindingof univalent antibody fragments to a distinct antigenic determinantof staphylococcal nuclease. Biochemistry 13: 1567-1571, 1974. |
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206. Sachs, D.H., Schechter, A.N., Eastlake, A. and Anfinsen, C.B.: Animmunologic distinction between possible origins of enzymatic activityin a polypeptide fragment of staphylococcal nuclease. Nature 251:242-244, 1974. |
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207. Anfinsen, C.B., Bose, S., Corley, L. and Gurari-Rotman, D.: Partialpurification of human interferon by affinity chromatography. Proc.Nat. Acad. Sci. U.S.A. 71: 3139-3142, 1974. |
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208. Anfinsen, C.B.: The Weizmann Institute of the past 15 years.Rehovot, 1974. |
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209. Furie, B., Schechter, A.N., Sachs, D.H. and Anfinsen, C. B.: Animmunological approach to the conformational equilibrium ofstaphylococcal nuclease. J. Mol. Biol. 92: 497-506, 1975. |
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210. Anfinsen, C.B. and Scheraga, H.A.: Experimental and theoreticalaspects of protein folding. In Anfinsen, C.B., Edsall, J.T. andRichards, F.M. (Eds): Advances in Protein Chemistry. New York,Academic Press, Inc., 1975, Vol.29, pp. 205-300. *(Not in collection) |
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211. Bose, S., Gurari-Rotman, D., Rüegg, U.Th., Corley, L. and Anfinsen, C.B.: Apparent dispensability of the carbohydrate moiety of human interferonfor antiviral activity. J. Biol. Chem. 251: 1659-1662, 1976. |
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212. Anfinsen, C.B.: One Hundred Years of Originality, Quality and Style.(Lecture given at the Centennial of the Carlsberg Laboratory, Copenhagen,September 27, 1976). Carlsberg Res. Commun. 41: 293-298, 1976. |
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213. Bridgen, P.J., Anfinsen, C.B., Corley, L., Bose, S., Zoon, K.C.,Ruegg, U.Th. and Buckler, C.E.: Human lymphoblastoid interferon:large scale production and partial purification. J. Biol. Chem. 252:6585-6587, 1977. |
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214. Zoon, K.C., Smith, M.E., Bridgen, P.J., zur Nedden, D. andAnfinsen, C.B.: Purification of human lymphoblastoid interferon.Interferon Workshop, Sloan-Kettering, 1979. *(Not in collection) |
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215. Anfinsen, C.B.: Biological synthesis of peptide hormones. MilesSymposium, 1979. *(Not in collection) |
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216. Zoon, K.C., Smith, M.E., Bridgen, P.J., zur Nedden, D. andAnfinsen, C.B.: Purification and partial characterization of humanlymphoblastoid interferon. Proc. Natl. Acad. Sci. USA 76: 5601-5605,1979. |
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217. Zoon, K.C., Smith, M.E., Bridgen, P.J. and Anfinsen, C.B.: Aminoterminal sequence of the major component of human lymphoblastoidinterferon. Science 207: 527-528, 1980. |
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218. Zoon, K.C., Smith, M.E., Bridgen, P.J., zur Nedden, D., Miller, D.M.and Anfinsen, C.B.: Human lymphoblastoid interferon: purification,amino acid composition and amino-terminal sequence. Ann. N.Y. Acad.Sci. 350: 390-398, 1980. |
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219. Anfinsen, C.B.: Human interferon. Interdisciplinary Science Reviews6: 110-118, 1981. |
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220. Smith, M.E., Komoriya, A. and Anfinsen, C.B.: Chemical Synthesis andProperties of Fragments of Human Leukocyte Interferon. In deMaeyer, E.,Galasso, G. and Schellekens, H. (Eds): The Biology of the InterferonSystem. New York, Elsevier/North Holland Biomed. Press, 1981. *(Not in collection) |
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221. Anfinsen, C.B.: The use of affinity chromatography in the study of protein fo1ding, in Affinity Chromatography and Biological Recognition, I. Chaiken, M. Wilchek, I. Parikh (Eds.). Orlando, Academic Press, 1983, pp. 355-361. *(includes draft) |
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222. Meadow, N., P. Coyle, A. Komoriya, C.B. Anfinsen, and S. Roseman: Limited proteolysis of IIIG1c, a regulatory protein of the phosphoenolpyruvate: Glycose phosphotransferase system, by membrane-associated enzymes from Salmonella typhimurium and Escherichia Coli. J. Biol. Chem. 261: 13504-13509, 1986. |
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223. Anfinsen, C.B.: Classical protein chemistry in a world of slicing and splicing, in Protein Engineering. Masayori, R. Sarma (Eds.), Orlando, Academic Press, 1986, pp. 3-13. |
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224. Rudzki, J., D. Shortle, D., C.B. Anfinsen, and L. Brand: Intrinsic fluorescence of wild type in mutant forms of staphylococcal nuclease. Biochemistry, submitted for publication 1987. *(Not in collection) |
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225. Skaja, A.K., C.B. Anfinsen, and M. Kelly. Use of high performance liquid affinity chromatography for protein recovery and thermostability analysis. November 1988. Annual Meeting, Wash., D.C. 1988. *(Not in collection) |
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226. Laderman, K.A., F.R. Davis, H.C. Krutzsch, M.C. Lewis, and C.B. Anfinsen. The purification and characterization of an extremely thermostable a-amylase from the hyperthermophilic archaebacterium Pyrococcus furiosus. J. Biol. Chem., 268, 24394-24401, 1993. |
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227. Laderman, K.A., B. Asada, T. Uemori, H. Mukai, Y. Taguchi, I. Koto and C-B. Anfinsen. a -Amylase from the hyperthemophilic archaebacterium Pyrococcus Furiosus. Cloning and sequencing of the gene and expression in Escherichia coli. J. Biol. Chem., 268, 24402-24407, 1993. |
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228. Stagsted, J., C. Capelli, C. Meyers, B.W. Matthews, C.B. Anfinsen, A. Goldstein and L. Olsson. Amino acid residues essential for biological activity of a peptide derived from a major histocompatibility complex class I antigen. Proc. Natl. Acad. Sci. USA, 90, 7686-7690, 1993. *(includes draft) |
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Kept with #50 Commentary by CBA on "Studies on the structural basis of ribonuclease activity" by CBA, W.F. Harrington, Aa. Hvidt, K. Linderstrom-Long, M. Ottesen and J. Schellman. Biochim. Biophys. Acta 17 (1955):141-142, reprinted in Biochim. Biophys. Acta 1000 (1989):197-199. |
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