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Total Risk Integrated Methodology (TRIM) -
TRIM.Risk
TRIM.Risk, the risk characterization module, is used to integrate the information on exposure received from TRIM.FaTE
(for ecological receptors) or TRIM.Expo (for human receptors) with that on dose-response or hazard assessment and to provide
quantitative descriptions of risk or hazard and some of the attendant uncertainties. The TRIM.Risk module and associated tools
provide the capability to summarize or highlight the major points from each of the analyses conducted in the TRIM modules. In
general, this includes: (1) documentation of assumptions and input data, (2) performance of risk calculations and data analysis,
and (3) presentation of results and supporting information.
An initial beta release of the TRIM.Risk module is projected for later this year. The intention is for future versions of TRIM.Risk
to provide the information required to prepare a full risk characterization. The initial release will provide the following
capabilities:
- calculation of a wide range of deterministic inhalation cancer risk and non-cancer hazard metrics at the individual and population level;
- calculation of the hazard quotient for a suite of ecological receptors; and
- a visualization tool for presenting analysis results in various automated formats.
Subsequent phases are expected to provide, among other enhancements, ingestion risk metrics and probabilistic simulations that
can be used to evaluate the uncertainty and variability inherent in modeling inhalation, ingestion, and ecological risk.
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