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The Distributed Structure-Searchable Toxicity (DSSTox)
Database Network provides a community forum for publishing standard
format, structure-annotated chemical toxicity data files for open
public access. Project goals are to:
Encourage use of DSSTox Standard
Chemical Structure Fields and SDF
standard format files for publishing chemical toxicity databases;
Coordinate with outside
public efforts to encourage chemical structure annotation, data
standardization, and open public access to toxicity databases;
Involve
the user community in the effort to migrate more public toxicity
data into the DSSTox standardized format for publishing;
Provide full, open access to toxicity data files for structure-analog
searching and for facilitating development of improved models for
predicting toxicity based on chemical structure.
| Distributed:
Decentralized set of standardized, field-delimited
databases, each separately authored and maintained, that
are able to accommodate diverse chemical toxicity data content;
Structure-Searchable:
Standard format (SDF) structure-data
files that can be readily imported into available Chemical
Relational Databases and structure-searched;
Tox: Toxicity data as it exists
in widely disparate forms in current public databases, spanning
diverse toxicity endpoints, test systems, levels of biological
content, degrees of summarization, and information content.
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