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Volume 10, Number 11, November 2004 Women and Autoimmune DiseasesDeLisa Fairweather* and Noel R. Rose* |
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Figure 6. Sex hormones increase myocarditis in female and male mice by increasing interleukin (IL)-1β and tumor necrosis factor (TNF)-α levels in the heart. Susceptible female (A,C) and male (B,D) BALB/c mice underwent gonadectomy (Fem op/Male op) and were compared to sham-operated controls (Fem sham/Male sham) for the level of myocarditis (% inflammation) and cytokines (pg/g) in the heart after CB3 infection. CB3 myocarditis was assessed for (A) female mice and (B) male mice after the operation. Data are represented as the mean ± standard error of the mean. *p < 0.05. |
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This page last reviewed October 22, 2004 |
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