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BIO - Directorate for Biological Sciences
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Division of Molecular and Cellular Biosciences
  Biomolecular Systems
  Cellular Systems
  Genes and Genome Systems
microscopic cells
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Cluster for Cellular Systems

This cluster supports research on the structure, function, and regulation of plant, animal, and microbial cells and their interactions with the environment and one another. Areas supported include studies of the structure, function, and assembly of cellular elements, such as the cytoskeleton, membranes, organelles, intracellular compartments, intranuclear structures, and extracellular matrix, including eukaryotic and prokaryotic cell walls and envelopes. In addition, support is provided for the study of intracellular and transmembrane signal transduction mechanisms and functions, and cell-cell signaling processes, including those that occur in biofilms. Research on cellular recognition and self defense mechanisms is included. Research utilizing both traditional and innovative methodologies, multidisciplinary approaches, technique development, computation and modeling, and approaches that exploit genomic information is encouraged. Multi-disciplinary approaches to the study of cellular systems, including research carried out at the interfaces of biology, physics, chemistry, mathematics and computer science, and engineering, are also encouraged.

This cluster includes the scientific themes of cellular organization and signal transduction and cellular regulation.

The Microbial Observatories and Microbial Interactions and Processes competition is also housed in this cluster. This expanded activity supports integrative studies that explore novel microorganisms, their interactions in consortia and communities, and aspects of their physiology, biochemistry and genomics in relationship to the processes that they carry out in the environments.

Cellular Organization

Signal Transduction and Cellular Regulation

Point of Contact: Cellular Systems Program Officers
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Last Modified: May 09, '03