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Carbosulfan (CASRN 55285-14-8)

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List of IRIS Substances Full IRIS Summary   QuickView   

Health assessment information on a chemical substance is included in IRIS only after a comprehensive review of toxicity data by U.S. EPA health scientists from several Program Offices, Regional Offices, and the Office of Research and Development.

Disclaimer: This QuickView represents a snapshot of key information. We suggest that you read the Full IRIS Summary to put this information into complete context.

For definitions of terms in the IRIS Web site, refer to the IRIS Glossary.

Status of Data for Carbosulfan


File First On-Line: 01/31/1987
Last Significant Revision: 01/31/1987
 
 Category Status Last Revised
Oral RfD Assessment On-line 12/01/1988
Inhalation RfC Assessment No data
Carcinogenicity Assessment No data


Chronic Health Hazard Assessments for Noncarcinogenic Effects

Reference Dose for Chronic Oral Exposure (RfD)


Critical Effect Experimental Dose
Decreased body weight NOEL : 1 mg/kg-day 100
1
1 x10-2 mg/kg-day
 

The Experimental Dose listed serves as a basis from which the Oral RfD was derived. See Discussion of Conversion Factors and Assumptions for more details.

Principal Study

2-year rat feeding study, FMC, 1982a

Confidence in the Oral RfD

Study -- High
Database -- High
RfD -- High

Reference Concentration for Chronic Inhalation Exposure (RfC)


Not Assessed under the IRIS Program.


Carcinogenicity Assessment for Lifetime Exposure

Weight of Evidence Characterization


Not Assessed under the IRIS Program.


Quantitative Estimate of Carcinogenic Risk from Oral Exposure


Not Assessed under the IRIS Program.


Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure


Not Assessed under the IRIS Program.


Revision History


Review Full IRIS Summary for complete
Revision History.


Synonyms


Carbosulfan
FMC 35001
55285-14-8
Advantage
((Dibutylamino)thio)methylcarbamic acid, 2,2-dimethyl-2,3-dihydro-7-benzofuranyl ester
2,3-Dihydro-2,2-dimethyl-7-benzofuranyl(di-N-butylaminosulfenyl)methylcarbamate
2,3-Dihydro-2,2-dimethyl-7-benzofuranyl((dibutylamino)thio) methyl carbamate
Marshal
Carbamic acid, ((dibutylamino)thio)methyl-, 2,2-dimethyl-2,3-dihydro-7-benzofuranyl ester

 

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Last Updated on Wednesday, November 3, 2004