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Chlorpyrifos (CASRN 2921-88-2)
Health assessment information on a chemical substance is included in IRIS only after a comprehensive review of toxicity data by U.S. EPA health scientists from several Program Offices, Regional Offices,
and the Office of Research and Development.
Disclaimer: This QuickView represents a snapshot of key information. We suggest that you read the Full IRIS Summary to put this information into complete context.
For definitions of terms in the IRIS Web site, refer to the IRIS Glossary.
Status of Data for Chlorpyrifos
File First On-Line: 01/31/1987
Last Significant Revision: 01/31/1987
| Oral RfD Assessment |
On-line |
03/01/1988 |
| Inhalation RfC Assessment |
No data |
|
| Carcinogenicity Assessment |
No data |
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Chronic Health Hazard Assessments for Noncarcinogenic Effects
Reference Dose for Chronic Oral Exposure (RfD)
| Decreased plasma ChE activity after 9 days |
NOEL :
0.03 mg/kg-day |
10
|
1
|
3 x10-3 mg/kg-day
|
The Experimental Dose listed serves as a basis from which the Oral RfD was derived. See Discussion of Conversion Factors and Assumptions for more details.
20-day human cholinesterase inhibition study, Dow Chemical, 1972
Study -- Medium
Database -- Medium
RfD -- Medium
Reference Concentration for Chronic Inhalation Exposure (RfC)
Not Assessed under the IRIS Program.
Carcinogenicity Assessment for Lifetime Exposure
Weight of Evidence Characterization
Not Assessed under the IRIS Program.
Quantitative Estimate of Carcinogenic Risk from Oral Exposure
Not Assessed under the IRIS Program.
Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure
Not Assessed under the IRIS Program.
Revision History
Review Full IRIS Summary for complete Revision
History.
Synonyms
2921-88-2
ENT 27311
NA 2783
Brodan
Chlorpyrifos
Chlorpyrifos-ethyl
DowCo 179
Dursban
Dursban F
Eradex
Ethion, dry
Lorsban
OMS-0971
o,o-Diaethyl-o-3,5,6-trichlor-2-pyridylmonothiophosphat
Phosphorothioic acid, o,o-diethyl o-(3,5,6-trichloro-2-pyridyl) ester
Pyrinex
Detmol U.A.
o,o-Diethyl o-3,5,6-trichloro-2-pyridyl phosphorothioate
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