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Benzoic acid (CASRN 65-85-0)


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Health assessment information on a chemical substance is included in IRIS only after a comprehensive review of toxicity data by U.S. EPA health scientists from several Program Offices, Regional Offices, and the Office of Research and Development.

Disclaimer: This QuickView represents a snapshot of key information. We suggest that you read the Full IRIS Summary to put this information into complete context.

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Status of Data for Benzoic acid

File First On-Line: 09/07/1988
Last Significant Revision: 06/01/1991

Category	Status	Last Revised
Oral RfD Assessment	On-line	07/01/1993
Inhalation RfC Assessment	No data
Carcinogenicity Assessment	On-line	05/01/1991

Chronic Health Hazard Assessments for Noncarcinogenic Effects

Reference Dose for Chronic Oral Exposure (RfD)

Critical Effect	Experimental Dose	UF	MF	RfD
No adverse effects observed	NOAEL : 4.4 mg/kg-day	1	1	4 mg/kg-day

The Experimental Dose listed serves as a basis from which the Oral RfD was derived. See Discussion of Conversion Factors and Assumptions for more details.

Principal Study

Human daily per capita intakes, FDA, 1973; Selected Committee on Review of the GRAS List

Confidence in the Oral RfD

Study -- Medium
Database -- Medium
RfD -- Medium

Reference Concentration for Chronic Inhalation Exposure (RfC)

Not Assessed under the IRIS Program.

Carcinogenicity Assessment for Lifetime Exposure

Weight of Evidence Characterization

Weight of Evidence (1986 US EPA Guidelines):
D (Not classifiable as to human carcinogenicity)

Weight of Evidence Narrative:
No human data and inadequate data from animal bioassays

This may be a synopsis of the full weight-of-evidence narrative. See Full IRIS Summary.

Quantitative Estimate of Carcinogenic Risk from Oral Exposure

Not Assessed under the IRIS Program.

Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure

Not Assessed under the IRIS Program.

Revision History

Review Full IRIS Summary for complete Revision History.

Synonyms

Phenyl carboxylic acid
65-85-0
Benzenecarboxylic acid
Benzoic acid
Carboxybenzene
Dracylic acid
Phenylformic acid

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