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1,2-Dichloropropane (CASRN 78-87-5)
Health assessment information on a chemical substance is included in IRIS only after a comprehensive review of toxicity data by U.S. EPA health scientists from several Program Offices, Regional Offices,
and the Office of Research and Development.
Disclaimer: This QuickView represents a snapshot of key information. We suggest that you read the Full IRIS Summary to put this information into complete context.
For definitions of terms in the IRIS Web site, refer to the IRIS Glossary.
Status of Data for 1,2-Dichloropropane
File First On-Line: 12/01/1991
Last Significant Revision: 12/01/1991
| Oral RfD Assessment |
No data |
|
| Inhalation RfC Assessment |
On-line |
12/01/1991 |
| Carcinogenicity Assessment |
No data |
|
Chronic Health Hazard Assessments for Noncarcinogenic Effects
Reference Dose for Chronic Oral Exposure (RfD)
Not Assessed under the IRIS Program.
Reference Concentration for Chronic Inhalation Exposure (RfC)
| Hyperplasia of the nasal mucosa |
LOAEL (HEC): 1.3 mg/m3 |
300
|
1
|
4x10-3 mg/m3
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The Experimental Dose listed serves as a basis from which the Inhalation RfC was derived. See Discussion of Conversion Factors and Assumptions for more details.
Rat 13-week inhalation study, Nitschke et al., 1988
Study -- High
Database -- Medium
RfC -- Medium
Carcinogenicity Assessment for Lifetime Exposure
Weight of Evidence Characterization
Not Assessed under the IRIS Program.
Quantitative Estimate of Carcinogenic Risk from Oral Exposure
Not Assessed under the IRIS Program.
Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure
Not Assessed under the IRIS Program.
Revision History
Review Full IRIS Summary for complete Revision
History.
Synonyms
Propylene dichloride
AI3-15406
alpha,beta-Dichloropropane
Bichlorure de propylene [French]
Caswell No. 324
CCRIS 951
Dichloro-1,2 propane [French]
Dicloruro de propileno [Spanish]
ENT 15,406
EPA Pesticide Chemical Code 029002
HSDB 1102
Propylene chloride
78-87-5
1,2-Dichloropropane
Dichlorure de propylene [French]
Dichloropropane
NCI-C55141
Propane, 1,2-dichloro-
alpha,beta-Propylene dichloride
Dwuchloropropan [Polish]
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