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OPPTS Harmonized Test Guidelines

Series 870 Health Effects Test Guidelines

The harmonized test guidelines have been developed for use in the testing of pesticides and toxic substances, and the development of test data that must be submitted to the Agency for review under Federal regulations.

PLEASE NOTE: Some of the items mentioned in this page are in Adobe's Portable Document Format (PDF). To view or print them you will need to have the Adobe Acrobat Reader program installed on your computer. The Reader can be downloaded and used with no charge. Click here for more information from EPA on PDF files.

Public Drafts

Guidelines in Public Draft
Master Guideline List (Adobe PDF file)
Summary of Draft Changes (Adobe pdf file)

Final Guidelines

Final Guidelines
Master Guideline List (Adobe PDF file)
Summary of Final Changes (HTML file)
Revised Final Guidelines (December 2002 and March 2003)




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