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08.31.2004 -- TIGR announces the initial release of Pathema, one of the new Bioinformatics Resource Centers funded by the National Institute of Allergy and Infectious Diseases (NIAID). Pathema will contain data on the genomes, genes and many functions related to pathogenicity on the complete set of NIAID category A-C bacterial pathogens. In addition, in-depth curatorial analysis of six bacterial pathogens will be available, including Bacillus anthracis, Clostridium botulinum, Francisella tularensis, Burkholderia mallei, Burkholderia pseudomallei, and Clostridium perfringens. The initial release of Pathema includes information about the future of the site. New tools will be added over the next year.


10.12.2004  
Computational Genomics Conference To Attract Leading Scientists
Comparative genomics, sequence assembly, gene expression analysis and genome annotation are among the hot topics to be discussed at the 7th annual Conference on Computational Genomics, which will be held October 21-24 in Reston, VA. The meeting is jointly sponsored by TIGR and The Jackson Laboratory.

09.21.2004  
Biothreat Pathogen's Genome Reveals Instability, Highly Regulated Virulence Genes
TIGR researchers have found that the horse pathogen Burkholderia mallei, which has been deployed in the past as a biological weapon, has an extremely regulated set of virulence genes and an unstable genome that may explain the bacterium's ability to thwart the immune responses of its host animals.

09.20.2004  
First Genome of Methane-Breathing Microbe is Deciphered
The first complete genome sequence of a methane-breathing bacterium, Methylococcus capsulatus, has revealed a surprising flexibility in its metabolism, suggesting an ability to live successfully in environments previously thought to be beyond its reach. The study by TIGR and Norwegian collaborators has implications for efforts to reduce biological methane emissions.

09.20.2004  
GSAC Conference Features Talks By Fauci, Wilson and other Eminent Scientists
Environmental genomics, human genomic medicine, biological energy production, evolutionary biology and new DNA sequencing technologies will be among the topics at the 16th International Genome Sequencing and Analysis Conference, to be held September 27-30 in Washington, D.C. Among the featured speakers will be Anthony S. Fauci, director of the National Institute of Allergy and Infectious Diseases (NIAID), and biologist E.O. Wilson of Harvard University. GSAC will also host a policy session on biodiversity and intellectual property issues.

08.30.2004  
Researchers Improve Detection of Diverse Anthrax Strains
Scientists at TIGR and in Arizona have capitalized on genomic data to define novel diagnostic tests and to gain insight into the evolutionary and genetic history of Bacillus anthracis, the deadly pathogen that causes anthrax.

07.30.2004  
Researchers embarked on two separate expeditions this week to explore microbial communities on deep-sea corals in the Gulf of Alaska and on shipwrecks in the Gulf of Mexico. Click here to track the Gulf of Alaska coral expedition, which includes TIGR scientists Naomi Ward and Kevin Penn. Click here to track the Gulf of Mexico shipwreck expedition, which includes TIGR's Garry Myers.

07.16.2004  
Bioinformatics Resource Center to Focus on Biothreat Pathogens
TIGR has signed a five-year, $21.1 million contract with the National Institute of Allergy and Infectious Diseases to establish and maintain a new national Bioinformatics Resource Center for the study of pathogens that are considered biothreat agents or are associated with emerging or re-emerging infectious diseases.

05.17.2004  
Anthrax Toxin Genes Found in Another Microbial Species
For the first time, researchers have found anthrax toxin genes in a naturally occurring microbe other than Bacillus anthracis, the bacterium that causes anthrax. The microbe that contains those anthrax genes is a strain of Bacillus cereus isolated from a patient with a medical condition similar to inhalation anthrax.

04.13.2004  
Sulfate-Breathing Bacterium's Genome is Deciphered
Paving the way for better methods to protect pipelines and remediate metallic pollutants, TIGR scientists and collaborators have deciphered the genome of a sulfate-breathing bacterium, Desulfovibrio vulgaris, which can damage oil and natural gas pipelines and corrode oilfield equipment.





Enrichment of Gene-Coding Sequences in Maize by Genome Filtration. Whitelaw, C.A. et al., Science (302), 2118-2120 (2003)

Genome of Geobacer sulfurreducens: Metal Reduction in Subsurface Environments. Methe, B.A. et al., Science (302), 1967-1969 (2003)