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Laboratory Information

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On this page:

•	Overviews
•	Testing & Presumptive Agent Identification
•	Biosafety
•	Shipping Specimens

•	Agent Access, Use, & Transfer Regulations, Registration
•	Training
•	Laboratory Response Network
•	Contacts

Overviews

•	CDC Laboratory Response Network (LRN) website NEW WEBSITE! Aug 27, 2004 Overview of the LRN, an integrated network of state & local public health, federal, military, & international labs that can respond to both bioterrorism & chemical terrorism.
•	CDC's Laboratory Response to Suspicious Substances Explains how federal, state, & local agencies respond to threatening letters & how labs play a role in detection & response.

Testing and Presumptive Agent Identification

•	Sentinel (formerly level A) laboratory procedures for identification of various agents Protocols for sentinel laboratories are no longer posted on this site. The American Society for Microbiology has agreed to take the lead in the development and dissemination of sentinel laboratory information. Sentinel procedures may now be accessed at http://www.asm.org/Policy/index.asp?bid=667. Information for reference laboratories will continue to be available on the Laboratory Response Network secure Website (for questions: e-mail lrn@cdc.gov; tollfree HelpDesk 1-866-LRN-LABS [1-866-576-5227]). The CDC subject matter experts on individual organisms remain available for discussion as always.
•	Chemical Terrorism Event Specimen Collection PDF (707 KB/1 page) NEW! May 19, 2004
•	Negative Staining Electron Microscopic Protocol for Rash Illness PDF (458 KB/8 pages) Instructions for laboratorians
•	*Presumptive Bacillus anthracis* Identification and Similar Organisms** PDF (72 KB/1 page) Table. WordPerfect (8 KB/1 page)
•	*Approved Tests for the Detection of Bacillus anthracis* in the U.S. Laboratory Response Network**
•	*Presumptive Brucella* spp. Identification and Similar Organisms** PDF (68 KB/1 page) Table. WordPerfect (8 KB/1 page)
•	Specimen Collection of Smallpox (Vaccinia) Vaccine Virus Step-by-step instructions for laboratorians PDF (126 KB/2 pages)
•	Smallpox Specimen Collection Guidelines PDF (98 KB/12 pages) From "Guide D" in the Smallpox Response Plan & Guidelines Word (101 KB/12 pages)
•	Specimen Selection PDF (303 KB/4 pages) Table. Selection, transport, storage, plating and processing, by disease agent. WordPerfect (29 KB/4 pages)
•	Spot Tests of Selected Organisms PDF (96 KB/1 page) Table. WordPerfect (10 KB/1 page)

Biosafety

•	Microbiology Biosafety PDF (303 KB/1 page) Table. Risk and precautions for Level A laboratories, by agent. WordPerfect (11 KB/1 page)
•	Vaccines PDF (57 KB/1 page) Table. Vaccine type, efficacy, comments, and requirements, by agent. WordPerfect (11 KB/1 page)
•	Summary of Biosafety Level 1 & 2 for Infectious Agents PDF (54 KB/2 pages) Table of primary and secondary containment methods, equipment, and facilities. WordPerfect (11 KB/2 pages)

Shipping Specimens

•	Packaging Protocols for Biological Agents/Diseases PDF (61 KB/5 pages)
•	Shipping Instructions for Samples Collected From People Potentially Exposed to Chemical Terrorism Agents PDF (102 KB/4 pages) Updated Jun 7, 2004 Includes illustrations and contact information. Word (686 KB/2 pages)

Agent Access, Use, and Transfer Regulations, Registration

•	Laboratory Registration/Select Agent Transfer Program Regulations regarding registration for access, use, and transfer of select agents for research purposes. From the Office of Health and Safety.

Training

•	Coping with Bioterrorism – The Role of the Laboratorian - Nov. 9, 2001 Archived video webcast & text transcript
•	National Laboratory Training Network (NLTN) Provides clinical, environmental, and public health laboratory training courses. Site includes extensive bioterrorism resources
•	Centers for Public Health Preparedness Helps local public health workers prepare to respond to health threats, including bioterrorism

Laboratory Response Network

•	Facts About the Laboratory Response Network UPDATED Aug 11, 2004 Description of the network of labs that respond to biological & chemical terrorism.
•	CDC Laboratory Response Network (LRN) website NEW WEBSITE! Aug 27, 2004 Overview of the LRN, an integrated network of state & local public health, federal, military, & international labs that can respond to both bioterrorism & chemical terrorism.

Contacts

•	Program questions: Centers for Disease Control and Prevention (CDC), Bioterrorism Preparedness and Response Program, 404-639-2797.
•	Training questions: Public Health Practice Program Office, Division of Laboratory Systems, 770-488-8295.

•	American Society for Microbiology



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