The 2003
Annual Report highlights significant events of the year's
research and provides a bibliography for each lab.
2002
Annual Report
2001
Annual Report
For more, visit the Publications
pages.
|
|
Section on Nervous System Development and Plasticity Monday, November 01, 2004 The Section on Nervous System Development and Plasticity is headed by Dr. R. Douglas Fields.
Research in our group is concerned with the cellular and molecular mechanisms of nervous system development, with particular emphasis on how neural impulse activity regulates development and plasticity of the nervous system. A molecular and electrophysiological approach is combined with live cell confocal imaging to investigate how patterned neural impulse activity is transduced into intracellular signaling networks to regulate expression of specific genes controlling development and synaptic plasticity. The scope of the section's investigations extends to activity-dependent interactions between neurons and glia and synaptic plasticity in the hippocampus. In cell culture and acute brain slice, the section studies mechanisms of activity-dependent communication between neurons and glia and the intracellular signaling pathways controlling gene expression necessary for long-term memory. The section's research has shown effects of impulse activity on cellular differentiation, axon outgrowth, synaptogenesis, synaptic remodeling, and myelination.
More Info on This Subject
In Other News...
|