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Alternative names Return to top
17-OHCSDefinition Return to top
The 17-hydroxycorticosteroids test measures the amount of 17-OHCS in urine.How the test is performed Return to top
A 24-hour urine sample is needed.How to prepare for the test Return to top
The health care provider will instruct you, if necessary, to discontinue drugs that may interfere with the test.How the test will feel Return to top
The test involves only normal urination, and there is no discomfort.Why the test is performed Return to top
Cortisol is a steroid hormone released from the adrenal cortex in response to adrenocorticotrophic hormone (ACTH). Cortisol is then metabolized into inactive products such as 17-OHCS by the liver and other tissues. These inactive products are excreted by the body in the urine. Measurements of 17-OHCS in the urine can be helpful in determining if the body is producing too much cortisol.
Normal Values Return to top
Normal values are as follows:
Note: mg/24 hr = milligrams per 24 hours
Normal value ranges may vary slightly among different laboratories.
What abnormal results mean Return to top
Elevated levels of 17-OHCS may indicate:What the risks are Return to top
There are no risks.Special considerations Return to top
Severe emotional or physical stress can affect the result.
Drugs that can increase 17-OHCS measurements include ampicillin and glucocorticoids.
Drugs that can decrease 17-OHCS measurements include: estrogens, oral contraceptives (birth control pills), and dexamethasone.
Update Date: 2/2/2004 Updated by: Tarun Jain, M.D., Endocrinology & Infertility Division, Brigham and Women's Hospital, Boston, MA. Review provided by VeriMed Healthcare Network.
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Page last updated: 28 October 2004 |