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Alternative names
Euglobulin clot lysis; Fibrinolysis/euglobulin lysisDefinition Return to top
This is a test that measures the euglobulin lysis time in blood. The euglobulin lysis time is a measure of the activity of the fibrinolytic (clot-breakdown) system.
How the test is performed Return to top
Blood is drawn from a vein (venipuncture), usually from the inside of the elbow or the back of the hand. The puncture site is cleaned with antiseptic, and a tourniquet (an elastic band) or blood pressure cuff is placed around the upper arm to apply pressure and restrict blood flow through the vein. This causes veins below the tourniquet to distend (fill with blood). A needle is inserted into the vein, and the blood is collected in an airtight vial or a syringe. During the procedure, the tourniquet is removed to restore circulation. Once the blood has been collected, the needle is removed, and the puncture site is covered to stop any bleeding.
Infant or young child:
The area is cleansed with antiseptic and punctured with a sharp needle or a lancet. The blood may be collected in a pipette (small glass tube), on a slide, onto a test strip, or into a small container. Cotton or a bandage may be applied to the puncture site if there is any continued bleeding.
How to prepare for the test Return to top
No special preparation is usually necessary.
Infants and children:
The physical and psychological preparation you can provide for this or any test or procedure depends on your child's age, interests, previous experiences, and level of trust. For specific information regarding how you can prepare your child, see the following topics as they correspond to your child's age:
How the test will feel Return to top
When the needle is inserted to draw blood, some people feel moderate pain, while others feel only a prick or stinging sensation. Afterward, there may be some throbbing.Why the test is performed Return to top
This is one of the best tests to differentiate primary fibrinolysis from DIC (disseminated intravascular coagulation). The test can also be used to monitor streptokinase or urokinase therapy in patients with acute MI (heart attack).Normal Values Return to top
A normal value will range from 90 minutes to 6 hours. Euglobulin clot lysis is normally complete within 2 to 4 hours.What abnormal results mean Return to top
In primary fibrinolysis (for example, caused by streptokinase administration, cancer of the prostate, shock), the euglobulin lysis time is shorter than normal.What the risks are Return to top
Special considerations Return to top
Veins and arteries vary in size from one patient to another, and from one side of the body to the other. Obtaining a blood sample from some people may be more difficult than from others.
Update Date: 5/8/2003 Updated by: Marcia S. Brose, M.D., Ph.D., Division of Hematology/Oncology, Hospital of the University of Pennsylvania, Philadelphia, PA. Review provided by VeriMed Healthcare Network.
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Page last updated: 28 October 2004 |