About the Human Genome Epidemiology Network Khoury-Dorman Editorial - Human Genome Epidemiology Network Feedback Form Human Genome Epidemiology (HuGE)- Translating Advances in Human Genetics into Population-based Data for Medicine and Public Health Expert Panel Convened To Develop Guidelines For Evaluating Human Genome Epidemiology Studies Rationale and HuGE Definition for the Human Genome Epidemiology Network Welcome message from Muin J. Khoury M.D., Ph.D., Director, Office of Genomics and Disease Prevention
HuGE Case Studies Comments for HuGE Case Studies FVL Case Study- FVL bibliography Case Study- Factor V Leiden and Venous Thrombosis Case Study- Factor V Leiden and Venous Thrombosis Overview Case Study- FVL Answers for printing Fictional Scenario: HuGE Case Study Case Study- Fictional Scenario bibliography Case Study- Fictional Scenario Case Study- Fictional Scenario Overview Case Study- Fictional Scenario Answers for printing NOD2 Case Study- NOD2 bibliography Case Study- NOD2 and Crohn Disease Case Study- NOD2 and Crohn Disease Overview Case Study- NOD2 and Crone Disease Answers for printing ODC Case Study: ODC bibliography Case Study: Pronounced reduction in adenoma recurrence associated with aspirin use and a polymorphism in the ornithine decarboxylase gene Case Study: ODC Overview
e-Journal Club Menu e-Journal Club Archive 5,10-Methylenetetrahydrofolate reductase codon 677 and 1298 polymorphisms and colon cancer in African Americans and whites Abstraction ACTN3 Variants and Athletic Performance Tables Implication of an AGT Haplotype in a Multigene Association Study With Pregnancy Hypertension Abstraction Angiotensinogen Gene Polymorphisms: Relationship to Blood Pressure Response to Antihypertensive Treatment Abstraction Alcohol Flushing, Alcohol and Aldehyde Dehydrogenase Genotypes, and Risk for Esophageal Squamous Cell Carcinoma in Japanese Men Abstraction Interaction of Smoking and Apolipoprotein E4 in CHD Risk in Men Abstraction Head circumference and incident Alzheimer's disease- modification by apolipoprotien E Abstraction Tea Intake, COMT Genotype, and Breast Cancer in Asian-American Women Abstraction Transforming Growth Factor-beta1 Promoter Polymorphism C-509T is Associated with Asthma Abstraction Breast cancer after prophylactic bilateral mastectomy in women with a BRCA1 and BRCA2 mutation Abstraction Primary pulmonary hypertension, herpesvirus-8 infection, and BMPR2 Transforming growth factor beta 1 polymorphism and breast cancer in older women Abstraction Impact of BRCA1-BRCA2 Mutation Testing on Psychologic Abstraction Association of the C677T polymorphisms in the MTHFR gene with breast and-or ovarian cancer risk in Jewish women. Abstraction Combined COMT and GST genotypes and hormone replacement therapy associated breast cancer risk Abstraction Parity, oral contraceptives, and the risk of ovarian cancer among carriers and noncarriers of a BRCA1 or BRCA2 mutation Abstraction NOD2 Variants and Crohn's Disease Abstraction Template for Hugot J-P, et al. Abstraction Template for Ogura Y, et al. Cardiovascular Disease and Estrogen Receptor Alpha Polymorphisms Abstraction CYP19, CYP1A1 Polymorphisms and ER-positive Breast Cancer Abstraction CYP2E1 Polymorphisms, Diet and Colorectal Cancer Abstraction Effects of Three DNA Repair Gene Polymorphisms on Bladder Cancer Risk Abstraction The DTNBP1 (Dysbindin) Gene Contributes to Schizophrenia, Depending on Family History of Disease Abstraction The ACE D/D Genotype is Protective Against the Development of Idiopathic Deep Vein Thrombosis and Pulmonary Embolism Abstraction A prospective study of asymptomatic carriers of the factor V Leiden mutation to determine the incidence of venous thromboembolism Abstraction Factor V Leiden Mutation and the Risk of Venous Thrombolembolism in Pregnant Women Abstraction Relation of an Interleukin-10 Promoter Polymorphism to Graft-versus-Host Disease and Survival after Hematopoietic-Cell Transplantation Abstraction Genetic polymorphism of GSTM1 and antioxidant supplementation influence lung function in relation to ozone exposure in asthmatic children in Mexico City Abstraction HLA Class I Alleles May Affect Susceptibility and Severity of SARS Abstraction Congestive heart failure and adrenergic receptor polymorphisms Abstraction Prevalence of hereditary hemochromatosis in late-onset type 1 diabetes mellitus- a retrospective study Abstraction Hormonal Replacement Therapy, Prothrombotic Mutations and the Risk of Venous Thrombosis Case Control Abstraction Information and Instructions for the e-Journal Club hugenet/files/print/guidelines.pdf Effects of Interleukin-1 Gene Polymorphisms and Chlamydia Pneumoniae Infection on the Development of Coronary Artery Disease Abstraction Interleukin-10, Polymorphism in SLC11A1 (formerly NRAMP1), and Susceptibility to Tuberculosis Abstraction Genomic Polymorphic Profiles in an Irish Population with Meningococcaemia: Is it Possible to Predict Severity and Outcome of Disease? Abstraction Joint Effect of the APOE Gene and Midlife Systolic Blood Pressure on Late-Life Cognitive Impairment- The Honolulu-Asia aging Study Abstraction Penetrance of 845G®A (C282Y) HFE hereditary haemochromatosis mutation in the USA Abstraction Effects of Hepatic Lipase Gene and Physical Activity on Coronary Heart Disease Risk Abstraction Unique Lipoprotein Phenotype and Genotype Associated with Exceptional Longevity Abstraction Comparative Study of the Two More Frequent HFE Mutations (C282Y and H63D)- Significant Different Allelic Frequencies Between the North and South of Portugal Abstraction Systemic lupus erythematosus and genetic variation in the interleukin 1 gene cluster: a population based study in the southeastern United States Abstraction Platelet Glycoprotein lb" HPA-2 Met-VNTR B haplotype as a genetic predictor of myocardial infarction and sudden cardiac death. Abstraction Effect of Expanded Newborn Screening for Biochemical Genetic Disorders on Child Outcomes and Parental Stress Abstraction NOD2 (CARD15) and Clinical Characteristics of Crohn's Disease Abstraction Low OGG activity may increase smokers' risk of lung cancer Abstraction SLC19A1 (RFC1) A80G Polymorphism, Maternal Multivitamin with Folate Use, and Orofacial and Conotruncal Heart Defects Abstraction Smoking, genetic polymorphisms in biotransformation enzymes, and nonsyndromic oral clefting- a gene-environment interaction Abstraction Smoking, folate and methylenetetrahydrofolate reductase status as interactive determinants of adenomatous and hyperplastic polyps of colorectum Abstraction Gene Interactions and Stroke Risk in Children with Sickle Cell Anemia Abstraction Tamoxifen and Breast Cancer Incidence Among Women with Inherited Mutations in BRCA1 and BRCA2 Abstraction Tumor necrosis factor A and MHC class I chain related gene A (MIC-A) polymorphisms in Swedish patients with cervical cancer Abstraction Polymorphism of the UCP2 promoter region and obesity Abstraction Vitamin D Receptor Gene Polymorphisms are Associated with Breast Cancer Risk in a UK Caucasian Population Abstraction Risk of Venous Thromboembolism after Air Travel: Interaction with Thrombophilia and Oral Contraceptives Abstraction XRCC1 Arg399Gln Polymorphism, Sunburn, and Non-melanoma Skin Cancer- Evidence of Gene-Environment Interaction. Abstraction XRCC3 Genetic Polymorphism, Smoking, and Lung Carcinoma Risk in Minority Populations Abstraction
HuGE Factsheets Fast Facts from HuGE ALAD Genotype and Lead Toxicity- HuGE factsheet hugenet/factsheets/print/ALADfactsheet.pdf Apolipoprotein E Polymorphism and Cardiovascular Disease Androgen Receptor Gene and Prostate Cancer - HuGE Factsheet CCR5 receptor gene and HIV infection- HuGE factsheet hugenet/factsheets/print/ccr5.pdf Catechol-O-Methyltransferase (COMT) Gene and Breast Cancer- HuGE factsheet FMR1 and the Fragile X Syndrome- HuGE factsheet GSTM1, GSTT1, and the Risk of Squamous Cell Carcinoma of the Head and Neck- HuGE factsheet hugenet/factsheets/print/GSTM1GSTT1.pdf Atopic Asthma and Interleukin-4 HuGE factsheet hugenet/factsheets/print/il-4.pdf IL2RG and Severe Combined Immunodeficiency (SCID), a Primary Immunodeficiency Disease (PID) - HuGE Factsheet Kaposi's Sarcoma and Interleukin-6- HuGE factsheet hugenet/factsheets/print/il6.pdf Medium-chain acyl-CoA dehydrogenase HuGE factsheet hugenet/factsheets/print/mcadd2.pdf Medium chain acyl-CoA dehydrogenase slide Mismatch Repair Genes hMLH1 and hMSH2 and Colorectal Cancer hugenet/reviews/mismatch.pdf HuGE Fact Sheet template and instructions HuGE Fact Sheet template and instructions
HuGE Reviews HuGENet™ Review Guidelines and Information Revised Guidelines and Format for HuGE Reviews, April 2003 Human Genome Epidemiologic Reviews: The Beginning of Something HuGE hugenet/files/print/2-3.pdf HuGE Review - Pooled Analysis of Alcohol Dehydrogenase Genotypes and Head and Neck Cancer hugenet/reviews/print/ADH1C.pdf HuGE Review - d-Aminolevulinic Acid Dehydratase (ALAD) Genotype and Lead Toxicity hugenet/reviews/print/ALAD.pdf Meta-Analysis of the Association of the Cathepsin D Ala224Val Gene Polymorphism with the Risk of Alzheimer's Disease hugenet/reviews/print/alzheimers.pdf HuGE Review - Androgen Receptor CAG Repeats and Prostate Cancer hugenet/reviews/print/prostate.pdf HuGE Review - HLA-DPB1 and Chronic Beryllium Disease hugenet/reviews/print/Beryllium.pdf HuGE Review - Apolipoprotein E Polymorphism and Cardiovascular Disease. hugenet/reviews/print/APOEcardio.pdf HuGE Review - GSTM1, GSTT1 & Risk of Squamous Cell Carcinoma of the Head & Neck hugenet/reviews/print/gstm1.pdf HuGE Review - CYP17 Gene Polymorphisms: Prevalence and Associations with Hormone Levels and Related Factors hugenet/reviews/print/gstm1.pdf HuGE Review - CYP3A4 Polymorphisms—Potential Risk Factors for Breast and Prostate Cancer hugenet/reviews/print/CYP3A4.pdf HuGE Review - HLA-DQ and Type 1 Diabetes hugenet/reviews/print/diabetes.pdf HuGE Review - Genetic Causes of Monogenic Heterozygous Familial Hypercholesterolemia HuGE Review - Familial Hypercholesterolemia and Coronary Heart Disease HuGE Review - Familial Hypercholesterolemia, Peripheral Arterial Disease, and Stroke HuGE review - FMR1 and the Fragile X Syndrome hugenet/reviews/print/fmr1.pdf HuGE Review - GJB2 (connexin 26) variants and nonsyndromic sensorineural hearing loss HuGE Review - Glutathione S Transferase Polymorphisms and Colorectal Cancer HuGE Review - Glutathione S-Transferase Polymorphisms and Risk of Ovarian Cancer HuGE Review - HFE Gene and Hereditary Hemochromatosis hugenet/reviews/print/hfe.pdf HuGE Review - Medium chain acyl-coA dehydrogenase deficiency (MCADD) HuGE Review - Mismatch Repair Genes hMLH1 and hMSH2 and Colorectal Cancer hugenet/reviews/print/mismatch.pdf HuGE Review - 5, 10-Methylenetetrahydrofolate reductase (MTHFR) Gene Variants and Congenital Anomalies hugenet/reviews/print/MTHFR.pdf HuGE Review - 5,10-Methylenetetrahydrofolate Reductase Polymorphisms and Leukemia Risk HuGE Review - N-Acetyltransferase Polymorphisms and Colorectal Cancer hugenet/reviews/print/n_acet.pdf Polymorphisms in Genes Involved in Folate Metabolism and Colorectal Neoplasia: A HuGE Review hugenet/reviews/print/neopasia.pdf HuGE Review - NF1 Gene and Neurofibromatosis Type 1 HuGE Review - NQO1 polymorphism-hematotoxicities with benzene exposure. hugenet/reviews/print/NQ01.pdf HuGE Review - Ovarian Cancer and Polymorphisms in the Androgen and Progesterone Receptor Genes hugenet/reviews/print/ov_cancer.pdf HuGE Review - Androgen Receptor CAG Repeats and Prostate Cancer Mutations in genes required for T-cell development: IL7R, CD45, IL2RG, JAK3, RAG1, RAG2, ARTEMIS, and ADA and severe combined immunodeficiency: HuGE review HuGE Review - Sickle Hemoglobin (Hb S) Allele and Sickle Cell Disease hugenet/reviews/print/sickle.pdf HuGE Review - Molecular Epidemiology of Vitamin D Receptor Gene Variants hugenet/reviews/print/vitd.pdf HuGE Review - Pooled analysis and meta-analysis of GSTM1 and bladder cancer
Information through books and video Genetics and Public Health in the 21st Century- Using Genetic Information to Improve Health and Prevent Disease Part 1 - Genetics and Public Health- An Overview; Chapter 1 - Genetics & Public Health- A Framework for the Integration of Human Genetics into Public Health Practice Part 2 - Public Health Assessment; Chapter 7 - Surveillance for Birth Defects & Genetic Diseases Part 2, Chapter 8 - Surveillance for Hemophilia and Inherited Hematologic Disorders Part 2; Chapter 9 - Public Health Assessment of Genetic Predisposition to Cancer Part 2; Chapter 10 - Public Health Assessment of Genetic Susceptibility to Infectious Diseases- Malaria, TB and HIV Part 2; Chapter 11 - Public Health Assessment of Genetic Information in the Occupational Setting Part 3 - Evaluation of Genetic Testing; Chapter 13 - Newborn Screening Quality Assurance Part 4 - Developing, Implementing, and Evaluating Population Interventions; Chapter 18 - Genetics and Prevention Effectiveness Part 4, Chap. 22 Newborn Screening for Sickle Cell Disease- Public Health Impact and Evaluation Part 4, Chap. 23 Public Health Strategies to Prevent the Complications of Hemochromatosis Part 5- Genetics and Public Health- Ethical, Legal, and Social Issues - Chap. 27 Public Health Surveillance of Genetic Information- Ethical and Legal Part 6- Communication, Education, and Information Dissemination - Chap. 31 Using the Internet to Disseminate Genetics Information for Public Health Genetic Epidemiology Epidemiology AJHG Book Review- Genetics and Public Health in the 21st Century AJHG Book Review AJMG- Genetics and Public Health in the 21st Century AJHG Book Review AJMG-PDF print version- Genetics and Public Health in the 21st Century Human Genome Epidemiology: A Scientific Foundation for Using Genetic Information to Improve Health and Prevent Disease Human Genome Epidemiology: Preface Chapter 1: Scope and Strategies Chapter 4: Ethical, Legal, and Social Issues in the Design and Conduct of Human Genome Epidemiologic Studies Chapter 5: Methods for Assessing Genotypes in Human Genome Epidemiology Studies Chapter 7: Facing the Challenge of Complex Genotypes and Gene-environment Interaction: the basic epidemiologic units in case-control and case-only designs Chapter 9: Applications of Human Genome Epidemiology to Environmental Health Chapter 10: Reporting and Review of Human Genome Epidemiology Studies Chapter 11: Epidemiologic Approach to Genetic Tests: Population-Based Data for Preventive Medicine Chapter 15: Integrating Genetics Into Randomized Controlled Trials Chapter 22: Immunogenetic Factors in Chronic Beryllium Disease Chapter 23: Fragile X Syndrome: Application of Gene Identification to Clinical Diagnosis and Population Screening Chapter 24: From Epidemiology to Clinical Practice: The Connexin Connection Chapter 28: Hereditary Hemochromatosis
Genetic conference materials online Abstracts from the first annual conference on genetics and public health Genetics in Public Health- Connecting Research, Education, Practice and Community Family History as a Tool for Public Health and Preventive Medicine Family History Abstracts Family History Wksp Agenda Family History Wksp Participants Family History Survey (Draft) Genomics Day Presentations 2nd National Conference - Menu Page 2nd Conference - Abstracts 2nd Conference - Overview 2nd Conference - Featured Speaker Biographies 2nd Conference - Sponsors 2nd Conference - Summary Overview of Scientific and Technological Advances in Genetics Overview of Societal Issues Genetics and Public Health List of Speakers 2nd Conference - Themes Human Genome Epidemiology Workshop- Using Genetic Information to Improve Health and Prevent Disease Role of Human Genetics in Infectious Diseases and Public Health Synopsis for Applying Genetic and Public Health Strategies to Primary Immunodeficiency Diseases PI Agenda PI Participants Developing A Strategic Plan to Assess the Feasibility, Utility, and Practical Implementation of Establishing a National/Multi-state Bank of Leftover Newborn Dried Blood Spots Genomics and Chronic Disease Summit
Genetic Testing for Breast and Ovarian Cancer Susceptibility Family History for Preventive Medicine and Public Health Frequently Asked Questions About the Role of Genetics in Public Health Frequently Asked Questions About Competencies for Genetics in Public Health Frequently Asked Questions About the Role of Genetics and Hemochromatosis Using Genetic Information to Improve Health and Prevent Disease Iron Overload due to Hereditary Hemochromatosis- CDC Program Activities and Priorities 2001 Screening for Iron Overload due to Hereditary Hemochromatosis Recognizing the Opportunities, Identifying Barriers, and Meeting the Challenges of Genomics and Public Health Pharmacogenomics- A Public Health Perspective Editorial Will Genetics Revolutionize Medicine? A Public Health Perspective. Making The Vision of Genomic Medicine A Reality- The Need for Public Health Research in The 21st Century
Genetic related presentations online slides info/slides/files/download/FHx_Initiative.zip CDC Priorities in Hemochromatosis, 2001 info/slides/files/download/hemoslide.ZIP Nature vs. Nurture slide Human Diseases Result from Gene-Environment Interactions info/slides/files/download/nvnslf.zip Pharmacogenomics and Public Health slide Which Odds Ratios Mean Something? info/slides/files/download/pharmaslf.ZIP Will Genetics Revolutionize Medicine slide info/slides/files/download/Revolutslf.ZIP The Vision of Genomic Medicine Developing a Public Health Genetics Research Agenda info/slides/files/download/researchslf.ZIP video Public Health Grand Rounds- Office of Genomics and Disease Prevention info/video/files/vertical brochure.pdf Human Genome Epidemiology: An Introduction Genetics and Public Health: An Introduction
Public Health Perspective Series Genetic Testing for Breast and Ovarian Cancer Susceptibility - A Public Health Perspective PHP - Genetic Testing for Breast and Ovarian Cancer Susceptibility Public Health Perspective Comments Family History as a Tool for Public Health and Preventive Medicine: A Public Health Perspective The Health Family Tree: Using Family History for Public Health Action Fact sheet: Family History for Preventive Medicine and Public Health Will Genetics Revolutionize Medicine- A Public Health Perspective Hereditary Hemochromatosis- Public Health Perspective The Completion of the Human Genome Project The Human Genome Project- A Public Health Perspective Informed Consent- A Public Health Perspective Nature vs. Nurture- An Unnecessary Debate Obesity and Genetics- A Public Health Perspective PHP- Obesity- Single gene disorders that have obesity as primary feature PHP- Obesity and Genetics PHP- Genetics and Obesity References PHP- Genetics and Obesity- What We Know, What We Don't Know and What It Means PHP- Obesity- Genetic polymorphisms and Quantitative Trait Loci (QTLs) associated with specific obesity sub-phenotypes info/perspectives/files/other/obeseknow.pdf Obesity and Genetics- A Public Health Perspective slide 1 Obesity and Genetics- A Public Health Perspective slide 2 Pharmacogenomics- A Public Health Perspective Public Health Perspective Response Page Genetic Testing- A Public Health Perspective ACCE- A CDC Sponsored Project Carried Out by the Foundation for Blood Research Introduction to Genetic Testing for the Public Health Perspective Making The Vision of Genomic Medicine A Reality- A Public Health Perspective
Genetic policy related reports and publications online Ethics in Epidemiology at the End of the Twentieth Century- Ethics, Values, and Mission Statements The Ethics of Access to Online Genetic Databases: Private or Public? Public Health Impact of Genetic Tests Tables Risks Associated with Genetic Testing- Health Insurance Discrimination or Simply Business as Usual? Informed Consent for Population-Based Research Involving Genetics - Intro Informed Consent for Population-Based Research Involving Genetics Informed Consent - Brochure Informed Consent - Template Informed Consent PHP - Editorial Consent for Genetic Research in a General Population:The NHANES Experience Letter to the Editor of Pediatrics- Early diagnosis of cystic fibrosis through neonatal screening... Press Release- CDC Panel Offers Recommendations to Inform Study Participants About Risks and Benefits of Genetic Research A Response from OGDP to an article by Dr. Francis Collins Ethical and Social Issues in the Use of Biomarkers in Epidemiologic Research
What Does Genetics Mean for Public Health Practice? Genetics and Public Health - Need for Information, Integration and Infrastructure Relationship Between Medical Genetics and Public Health- Changing the Paradigm of Disease Prevention and the Definition of a Genetic Disease Challenges in Communicating Genetics - A Public Health Approach The Intersection of Genetics, Public Health, and Preventive Medicine Physicians' Perceived Usefulness of and Satisfaction with Test Reports for Cystic Fibrosis (ΔF508) and Factor V Leiden Data Systems, Data Linkages, and Data for Decision Making Human Diversity - Impact on Genetic Testing and Screening On the Use of Population-based Registries in the Clinical Validation of Genetic Tests for Disease Susceptibility Genetics and Genomics in Practice: The Continuum from Genetic Disease to Genetic Information in Health and Disease Hereditary Hemochromatosis: Perspectives of Public Health, Medical Genetics, and Primary Care Hereditary Hemochromatosis- Preventing Chronic Effects of this Underdiagnosed Disorder Helping high-risk families- Medical and public health approaches Human Genetics and Emerging Infectious Diseases- Issues and Prevention Opportunities International Genetic Testing Population Screening in the Age of Genomic Medicine Journal Publication - What Does Genetics Mean for Public Health Practice? Is the G985A Allelic Variant of Medium Chain Acyl-CoA Dehydrogenase (MCAD) a Risk Factor for Sudden Infant Death Syndrome (SIDS)? A Pooled Analysis. The Role of State Public Health Agencies in Genetics and Disease Prevention- Results of a National Survey
Genetic health studies research related reports and publications online Genetic research methods related reports and publications online Increased Frequency of Cystic Fibrosis among Infants with Jejunoileal Atresia Can family history be used as a tool for public health and preventive medicine? Public attitudes regarding the donation and storage of blood specimens for genetic research Exploring gene-gene interactions in the etiology of neural tube defects Family History Score as a Predictor of Breast Cancer Mortality: Prospective data from the Cancer Prevention Study II, United States, 1982-1991 Genetic Susceptibility to Birth Defects in Humans- From Gene Discovery to Public Health Action Mutations in the Genes Regulationg Methylene Tetrahydrofolate Reductase (MTHFR C->T677) and Cystathione Synthase (CBS G->A919, CBS T->C833) Are Not Associated with Myocadial Infarction in African-Americans Elevated Rates of Severe Neural Tube Defects in a High-Prevalence Area in Northern China Frequently Asked Questions About the Role of Genetics in Public Health Long-term developmental outcomes of children identified through a newborn screening program with a metabolic or endocrine disorder: a population-based approach Epidemiologic Evaluation of the Use of Genetics to Improve the Predictive Value of Disease Risk Factors Evolving Methods in Genetic Epidemiology Family History Assessment: Strategies for Prevention of Cardiovascular Disease Research Priorities for Evaluating Family History in the Prevention of Common Chronic Diseases Using decision analytic methods to assess the utility of family history tools Population-based estimates of the prevalence of family history of cancer among women Genetic Epidemiology and the Future of Disease Prevention and Public Health The Future of Genetic Studies of Complex Human Diseases- An Epidemiologic Perspective Genetic and Epidemiologic Approaches to the Search for Gene-Environment Interaction- the Case of Osteoporosis - CDC Office of Genetics and Disease Prevention Case-Only Design to Measure Gene-Gene Interaction - CDC Office of Genetics and Disease Prevention HFE genotype and transferrin saturation in the United States Mendelian randomisation: a new spin or real progress? von Willebrand Disease and Other Inherited Bleeding Disorders In Women with Diagnosed Menorrhagia - CDC Office of Genomics and Disease Prevention Is Mutated Methylenetetrahydrafolate Reductase (MTHFR) a Risk Factor for Neural Tube Defects? A Pooled Analysis Analysis of mortality in neurofibromatosis 1 using U.S. death certificates Increased Risk for Familial Ovarian Cancer Among Jewish Women- A Population-Based Case-Control Study Platelet Glycoprotein Receptor IIIa Polymorphism PlA2 and Ischemic Stroke Risk - CDC Office of Genomics and Disease Prevention Regional variation in CCR5-Delta32 gene distribution among women from the US HIV Epidemiology Research Study (HERS) On the Use of Population Attributable Fraction to Determine Sample Size for Case-Control Studies of Gene-Environment Interaction Research Priorities for Public Health Sciences in the Post-Genomic Era An epidemiologic assessment of genomic profiling for measuring susceptibility to common diseases and targeting interventions A Review of Genetic Polymorphisms and Prostate Cancer Risk. The Role of Activated Protein C Resistance in the Pathogenesis of Venous Thrombosis - CDC Office of Genomics and Disease Prevention Sample Size Requirements in Case-only Designs to Detect Gene-environment Interaction Is the G985A Allelic Variant of Medium Chain Acyl-CoA Dehydrogenase (MCAD) a Risk Factor for Sudden Infant Death Syndrome (SIDS)? A Pooled Analysis. Spina Bifida and Folate-Related Genes: A Study of Gene-Gene Interactions Public Knowledge Regarding the Role of Genetic Susceptibility to Environmentally Induced Health Conditions Improving the Prediction of Complex Diseases by Testing for Multiple Disease-Susceptibility Genes Thrombosis In Pregnancy- The Role of Factor V Leiden, Prothrombin 20210 G to A, Angiotensin Converting Enzyme and Methylenetetrahydrofolate Reductase in a U.S. Population - CDC Office of Genetics and Disease Prevention Population Study of Congenital Hypothyroidism and Associated Birth Defects - CDC Office of Genetics and Disease Prevention Tumor Necrosis Factor-a Promoter Variant 2 (TNF2) is Associated with Pre-Term Delivery, Infant Mortality, and Malaria Morbidity in Western Kenya- Asembo Bay Cohort Project IX Trends and Patterns of Mortality - CDC Office of Genomics and Disease Prevention Risk Factors for Trisomy 21- Maternal Cigarette Smoking and Oral Contraceptive Use in a Population-Based Case-Control Study - CDC Office of Genetics and Disease Prevention The Relationship of Three Genetic Traits to Venous Thrombosis in an African-American Population - CDC Office of Genomics and Disease Prevention The Integration of Genomics into Public Health Research, Policy, and Practice in the United States Contribution of Birth Defects and Genetic Diseases to Pediatric Hospitalizations- A Population-Based Study - CDC Office of Genetics and Disease Prevention FBR CommentForm.htm FBR/Analytic.pdf FBR/ClinicalUtility.pdf FBR/ClinicalValidity.pdf FBR/Disorder.pdf FBR/ELSIJune2002.pdf FBR/Introduction.pdf FBR/Glossary.pdf
External Links for Office of Genomics and Disease Prevention
Training and Education for Genetics and Public Health
Archive for the Weekly Update, HuGE What's New, and HuGE Literature
Top of page