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Contents of this page: | |
Alternative names
Hydrocortisone testDefinition Return to top
A cortisol level is a blood test that measures the amount of cortisol, a steroid hormone produced by the adrenal cortex.How the test is performed Return to top
Adult or child:How to prepare for the test Return to top
The health care provider may advise you to discontinue drugs that can affect the test (see also "Special considerations"). Drugs that can increase cortisol measurements include estrogen and synthetic glucocorticoids, like prednisone and prednisolone. Drugs that can decrease cortisol measurements include androgens and phenytoin.How the test will feel Return to top
When the needle is inserted to draw blood, some people feel moderate pain, while others feel only a prick or stinging sensation. Afterward, there may be some throbbing.Why the test is performed Return to top
Cortisol levels are often measured to evaluate the pituitary and adrenal function.Normal Values Return to top
Normal values at 8 a.m.are 6 to 23 mcg/dl. Normal value ranges may vary slightly among different laboratories.What abnormal results mean Return to top
Greater than normal levels may indicate:What the risks are Return to top
Special considerations Return to top
Cortisol is a steroid hormone released from the adrenal cortex in response to ACTH. Normally, cortisol levels rise and fall during the day, repeating on a 24-hour cycle (diurnal variation). Highest levels are at about 6 to 8 a.m. and lowest levels are at about midnight.
Physical and emotional stress can increase serum cortisol, because a normal response to stress involves increased secretion of ACTH by the pituitary gland.
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Page last updated: 28 October 2004 |