NSF LogoNSF Award Abstract - #0304097 AWSFL008-DS3

NIRT: Rationally Designed Nanosensing Substrates for Chemical and Biodetection

NSF Org EEC
Latest Amendment Date August 14, 2003
Award Number 0304097
Award Instrument Standard Grant
Program Manager Tapan Mukherjee
EEC DIV OF ENGINEERING EDUCATION AND CENTERS
ENG DIRECTORATE FOR ENGINEERING
Start Date August 15, 2003
Expires July 31, 2007 (Estimated)
Expected Total Amount $1521288 (Estimated)
Investigator Naomi J. Halas halas@rice.edu (Principal Investigator current)
Bruce R. Johnson (Co-Principal Investigator current)
Mehmet Sarikaya (Co-Principal Investigator current)
Peter A. Nordlander (Co-Principal Investigator current)
Jeffrey D. Hartgerink (Co-Principal Investigator current)
Sponsor William Marsh Rice Univ
6100 Main Street, MS-16
Houston, TX 772511892 713/348-4820
NSF Program 1480 ENGINEERING RESEARCH CENTERS
Field Application
Program Reference Code 0000,1674,5918,OTHR,

Abstract

EEC-0304097 William Marsh Rice University Halas

The objective of this 48-month project is to investigate surface enhanced spectroscopy as a sensing tool for the nanostructure-enhanced chemical and biological detection, with a focus on minimal sample preparation and sample contact. The research goals include: (1) to design, construct and optimize nanostructure-based substrates for ultra sensitive detection of molecules based on Surface Plasmon Resonance Spectroscopy, Surface Enhanced Raman Spectroscopy, Fluorescence Spectroscopy, and Surface Enhanced Infrared Spectroscopy; (2) to develop a comprehensive fundamental understanding of nanostructure-enhanced chemical detection by accurately modeling the substrate, the molecule and the near field at the substrate-molecule interface., and (3) to apply this fundamental understanding to the chemical detection of small molecules, functional groups characteristic of chemical, biological and explosive agents, to proteins and ultimately to micron-sized protein-coated objects.


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